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The Association of Coloproctology of Great Britain and Ireland guideline on the management of anal fissure.
Cross KLR, Brown SR, Kleijnen J, Bunce J, Paul M, Pilkington S, Warren O, Jones O, Lund J, Goss HJ, Stanton M, Marunda T, Gilani A, Ngu LWS, Tozer P. Cross KLR, et al. Among authors: kleijnen j. Colorectal Dis. 2023 Dec;25(12):2423-2457. doi: 10.1111/codi.16762. Epub 2023 Nov 5. Colorectal Dis. 2023. PMID: 37926920 Review.
RESULTS: This guideline is divided into two sections: Primary care which includes (i) diagnosis; (ii) basic treatment; (iii) topical treatment; and secondary care which includes (iv) botulinum toxin therapy; (v) surgical intervention and (vi) special situations (including pregnan …
RESULTS: This guideline is divided into two sections: Primary care which includes (i) diagnosis; (ii) basic treatment; (iii) topical treatme …
Digital interventions to moderate alcohol consumption in young people: a Cancer Prevention Europe overview of systematic reviews.
McDermott KT, Noake C, Wolff R, Espina C, Foucaud J, Steindorf K, Schüz J, Thorat MA, Weijenberg M, Bauld L, Kleijnen J. McDermott KT, et al. Among authors: kleijnen j. Front Digit Health. 2023 May 23;5:1178407. doi: 10.3389/fdgth.2023.1178407. eCollection 2023. Front Digit Health. 2023. PMID: 37288171 Free PMC article. Review.
In risky drinkers, stand-alone Computerized interventions reduced short (SMD: -0.17, 95% CI: -0.27 to -0.08) and long term (SMD: -0.17, 95% CI: -0.30 to -0.04) alcohol consumption compared to no intervention, while a small effect (SMD: -0.15, 95% CI: -0.25 to -0.06) in fav …
In risky drinkers, stand-alone Computerized interventions reduced short (SMD: -0.17, 95% CI: -0.27 to -0.08) and long term (SMD: -0.1 …
Abemaciclib in Combination with Endocrine Therapy for Adjuvant Treatment of Hormone Receptor-Positive, HER2-Negative, Node-Positive Early Breast Cancer: An Evidence Review Group Perspective of a NICE Single Technology Appraisal.
Orozco Leal G, Armstrong N, Kernohan A, Ahmadu C, Coughlan D, McDermott K, Duffy S, O'Meara S, Robinson T, Vale L, Kleijnen J. Orozco Leal G, et al. Among authors: kleijnen j. Pharmacoeconomics. 2023 Jul;41(7):741-750. doi: 10.1007/s40273-023-01259-6. Epub 2023 Mar 23. Pharmacoeconomics. 2023. PMID: 36952138 Free PMC article. Review.
The ERG believed that the modelling structure presented in the de novo economic model by the company was appropriate but highlighted several areas of uncertainty that had the potential to have a significant impact on the resulting incremental cost-effectiveness ratio (ICER). Area …
The ERG believed that the modelling structure presented in the de novo economic model by the company was appropriate but highlighted several …
Belimumab for Treating Active Autoantibody-Positive Systemic Lupus Erythematosus: An Evidence Review Group Perspective of a NICE Single Technology Appraisal.
Otten T, Riemsma R, Wijnen B, Armstrong N, Stirk L, Gordon C, Ramaekers B, Kleijnen J, Joore M, Grimm S. Otten T, et al. Among authors: kleijnen j. Pharmacoeconomics. 2022 Sep;40(9):851-861. doi: 10.1007/s40273-022-01166-2. Epub 2022 Jul 8. Pharmacoeconomics. 2022. PMID: 35802295 Free PMC article. Review.
The ERG identified three major concerns with the evidence presented on the clinical effectiveness in the current submission; namely, short follow-up in the main comparative trials (BLISS-SC, BLISS-52 and BLISS-76); using the propensity score-matching (PSM) analysis in calibrating …
The ERG identified three major concerns with the evidence presented on the clinical effectiveness in the current submission; namely, short f …
Transcatheter aortic valve implantation versus surgical aortic valve replacement in patients with severe aortic stenosis: a systematic review and meta-analysis.
Swift SL, Puehler T, Misso K, Lang SH, Forbes C, Kleijnen J, Danner M, Kuhn C, Haneya A, Seoudy H, Cremer J, Frey N, Lutter G, Wolff R, Scheibler F, Wehkamp K, Frank D. Swift SL, et al. Among authors: kleijnen j. BMJ Open. 2021 Dec 6;11(12):e054222. doi: 10.1136/bmjopen-2021-054222. BMJ Open. 2021. PMID: 34873012 Free PMC article.
TAVI may reduce the risk of certain side effects while SAVR may reduce the risk of others. Most long-term (5-year) results are limited to older patients at high surgical risk (ie, early trials), therefore more data are required for low risk populations. ...
TAVI may reduce the risk of certain side effects while SAVR may reduce the risk of others. Most long-term (5-year) results are limite …
High-sensitivity troponin assays for early rule-out of acute myocardial infarction in people with acute chest pain: a systematic review and economic evaluation.
Westwood M, Ramaekers B, Grimm S, Worthy G, Fayter D, Armstrong N, Buksnys T, Ross J, Joore M, Kleijnen J. Westwood M, et al. Among authors: kleijnen j. Health Technol Assess. 2021 May;25(33):1-276. doi: 10.3310/hta25330. Health Technol Assess. 2021. PMID: 34061019 Free PMC article.
The bivariate model was used to estimate summary sensitivity and specificity for meta-analyses involving four or more studies; otherwise, random-effects logistic regression was used. The health economic analysis considered the long-term costs and quality-adjusted life-year …
The bivariate model was used to estimate summary sensitivity and specificity for meta-analyses involving four or more studies; otherwise, ra …
Avatrombopag and lusutrombopag for thrombocytopenia in people with chronic liver disease needing an elective procedure: a systematic review and cost-effectiveness analysis.
Armstrong N, Büyükkaramikli N, Penton H, Riemsma R, Wetzelaer P, Huertas Carrera V, Swift S, Drachen T, Raatz H, Ryder S, Shah D, Buksnys T, Worthy G, Duffy S, Al M, Kleijnen J. Armstrong N, et al. Among authors: kleijnen j. Health Technol Assess. 2020 Oct;24(51):1-220. doi: 10.3310/hta24510. Health Technol Assess. 2020. PMID: 33108266 Free PMC article.
When assessing the cost-effectiveness of lusutrombopag and avatrombopag, it was found that, despite the success of these in avoiding platelet transfusions prior to surgery, the additional long-term gain in quality-adjusted life-years was very small. No thrombopoietin recep …
When assessing the cost-effectiveness of lusutrombopag and avatrombopag, it was found that, despite the success of these in avoiding platele …
Transarterial (chemo)embolisation versus no intervention or placebo for liver metastases.
Swierz MJ, Storman D, Riemsma RP, Wolff R, Mitus JW, Pedziwiatr M, Kleijnen J, Bala MM. Swierz MJ, et al. Among authors: kleijnen j. Cochrane Database Syst Rev. 2020 Mar 12;3(3):CD009498. doi: 10.1002/14651858.CD009498.pub4. Cochrane Database Syst Rev. 2020. PMID: 32163181 Free PMC article.
Liver metastases are significantly more common than primary liver cancer, and long-term survival rate after radical surgical treatment is approximately 50%. ...The trial did not measure failure to clear liver metastases, time to progression of liver metastases, tumour resp …
Liver metastases are significantly more common than primary liver cancer, and long-term survival rate after radical surgical treatmen …
Percutaneous ethanol injection for liver metastases.
Swierz MJ, Storman D, Riemsma RP, Wolff R, Mitus JW, Pedziwiatr M, Kleijnen J, Bala MM. Swierz MJ, et al. Among authors: kleijnen j. Cochrane Database Syst Rev. 2020 Feb 4;2(2):CD008717. doi: 10.1002/14651858.CD008717.pub3. Cochrane Database Syst Rev. 2020. PMID: 32017845 Free PMC article.
Liver metastases are significantly more common than primary liver cancer, and the reported long-term survival rate after radical surgical treatment is approximately 50%. ...
Liver metastases are significantly more common than primary liver cancer, and the reported long-term survival rate after radical surg …
Fluocinolone Acetonide Intravitreal Implant for Treating Recurrent Non-infectious Uveitis: An Evidence Review Group Perspective of a NICE Single Technology Appraisal.
Pouwels XGLV, Petersohn S, Carrera VH, Denniston AK, Chalker A, Raatz H, Armstrong N, Shah D, Witlox W, Worthy G, Noake C, Riemsma R, Kleijnen J, Joore MA. Pouwels XGLV, et al. Among authors: kleijnen j. Pharmacoeconomics. 2020 May;38(5):431-441. doi: 10.1007/s40273-019-00851-z. Pharmacoeconomics. 2020. PMID: 31701471 Free PMC article. Review.
Additionally, the quality of life of patients was not measured during the PSV-FAI-001 trial and long-term effectiveness data of FAc were lacking. The ERG adjusted several issues identified in the CS and added dexamethasone as a comparator in the decision analytic model. .. …
Additionally, the quality of life of patients was not measured during the PSV-FAI-001 trial and long-term effectiveness data of FAc w …
46 results