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Page 1
Minimal dose for effective clinical outcome and predictive factors for responsiveness to carvedilol: Japanese chronic heart failure (J-CHF) study.
Okamoto H, Hori M, Matsuzaki M, Tsutsui H, Yamazaki T, Nagai R, Yoshikawa T, Fujio Y, Nonen S, Azuma J, Izumi T, Ohashi Y, Kitabatake A; J-CHF Investigators. Okamoto H, et al. Among authors: kitabatake a. Int J Cardiol. 2013 Apr 5;164(2):238-44. doi: 10.1016/j.ijcard.2012.11.051. Epub 2012 Dec 12. Int J Cardiol. 2013. PMID: 23245621 Free article. Clinical Trial.
Multivariate analysis indicated early decreases in HR and BNP predicted long-term outcomes. However, adverse events increased dose-dependently. ...Carvedilol therapy should be guided by reductions in HR and/or BNP, especially by initial HR reduction, but not only by its do …
Multivariate analysis indicated early decreases in HR and BNP predicted long-term outcomes. However, adverse events increased dose-de …
The change in low-density lipoprotein cholesterol concentration is positively related to plasma docosahexaenoic acid but not eicosapentaenoic acid.
Itakura H, Yokoyama M, Matsuzaki M, Saito Y, Origasa H, Ishikawa Y, Oikawa S, Sasaki J, Hishida H, Kita T, Kitabatake A, Nakaya N, Sakata T, Shimada K, Shirato K, Matsuzawa Y; JELIS. Itakura H, et al. Among authors: kitabatake a. J Atheroscler Thromb. 2012;19(7):673-9. doi: 10.5551/jat.11593. Epub 2012 May 26. J Atheroscler Thromb. 2012. PMID: 22653220 Free article. Clinical Trial.
AIM: The Japan EPA Lipid Intervention Study (JELIS) reported a 19% reduction of the risk for coronary artery disease after long-term use of pure eicosapentaenoic acid (EPA) in Japanese patients with hypercholesterolemia. ...
AIM: The Japan EPA Lipid Intervention Study (JELIS) reported a 19% reduction of the risk for coronary artery disease after long-term …
Percutaneous coronary intervention plus medical therapy reduces the incidence of acute coronary syndrome more effectively than initial medical therapy only among patients with low-risk coronary artery disease a randomized, comparative, multicenter study.
Nishigaki K, Yamazaki T, Kitabatake A, Yamaguchi T, Kanmatsuse K, Kodama I, Takekoshi N, Tomoike H, Hori M, Matsuzaki M, Takeshita A, Shimbo T, Fujiwara H; Japanese Stable Angina Pectoris Study Investigators. Nishigaki K, et al. Among authors: kitabatake a. JACC Cardiovasc Interv. 2008 Oct;1(5):469-79. doi: 10.1016/j.jcin.2008.08.002. JACC Cardiovasc Interv. 2008. PMID: 19463347 Free article. Clinical Trial.
BACKGROUND: Several multicenter studies have suggested that in the above patients, an initial management strategy of PCI+MT does not reduce the long-term risk of cardiovascular events more effectively than initial MT only. ...CONCLUSIONS: In stable low-risk CAD, PCI+MT may …
BACKGROUND: Several multicenter studies have suggested that in the above patients, an initial management strategy of PCI+MT does not reduce …
Effects of eicosapentaenoic acid on major coronary events in hypercholesterolaemic patients (JELIS): a randomised open-label, blinded endpoint analysis.
Yokoyama M, Origasa H, Matsuzaki M, Matsuzawa Y, Saito Y, Ishikawa Y, Oikawa S, Sasaki J, Hishida H, Itakura H, Kita T, Kitabatake A, Nakaya N, Sakata T, Shimada K, Shirato K; Japan EPA lipid intervention study (JELIS) Investigators. Yokoyama M, et al. Among authors: kitabatake a. Lancet. 2007 Mar 31;369(9567):1090-8. doi: 10.1016/S0140-6736(07)60527-3. Lancet. 2007. PMID: 17398308 Clinical Trial.
BACKGROUND: Epidemiological and clinical evidence suggests that an increased intake of long-chain n-3 fatty acids protects against mortality from coronary artery disease. We aimed to test the hypothesis that long-term use of eicosapentaenoic acid (EPA) is effective for pre …
BACKGROUND: Epidemiological and clinical evidence suggests that an increased intake of long-chain n-3 fatty acids protects against mortality …
Brain expression of VEGF and its receptors in SHR-SP and effects of an endothelin blocker.
Jesmin S, Sakuma I, Togashi H, Yoshioka M, Hattori Y, Kitabatake A, Miyauchi T. Jesmin S, et al. Among authors: kitabatake a. J Cardiovasc Pharmacol. 2004 Nov;44 Suppl 1:S160-4. doi: 10.1097/01.fjc.0000166264.27476.60. J Cardiovasc Pharmacol. 2004. PMID: 15838270
We had observed that vascular endothelial growth factor and its receptors, kinase domain region (KDR) and fms-like tyrosine kinase (Flt-1), were upregulated in the frontal cortex of spontaneously hypertensive stroke-prone rats at the typical hypertensive stage. The current study …
We had observed that vascular endothelial growth factor and its receptors, kinase domain region (KDR) and fms-like tyrosine kinase (Flt-1), …
Expression of endothelin receptors in the brain of SHR-SP and effects of an endothelin blocker.
Jesmin S, Sakuma I, Togashi H, Yoshioka M, Hattori Y, Kitabatake A, Miyauchi T. Jesmin S, et al. Among authors: kitabatake a. J Cardiovasc Pharmacol. 2004 Nov;44 Suppl 1:S156-9. doi: 10.1097/01.fjc.0000166258.96980.23. J Cardiovasc Pharmacol. 2004. PMID: 15838268
This is the first study to explore the relative endothelin receptor distribution in the frontal cortex of SHR-SP at the typical hypertensive stage and changes resulting from long-term endothelin antagonism starting from the prehypertensive stage....
This is the first study to explore the relative endothelin receptor distribution in the frontal cortex of SHR-SP at the typical hypertensive …
An S-nitrosylated hemoglobin derivative protects the rat hippocampus from ischemia-induced long-term potentiation impairment with a time window.
Otani H, Jesmin S, Togashi H, Sakuma I, Nakai K, Satoh H, Yoshioka M, Kitabatake A. Otani H, et al. Among authors: kitabatake a. J Pharmacol Sci. 2004 Oct;96(2):188-98. doi: 10.1254/jphs.fp0040385. Epub 2004 Oct 9. J Pharmacol Sci. 2004. PMID: 15492465 Free article.
The aim of the present study was to elucidate the effects of S-nitrosylated (SNO) polyethylene glycol-conjugated (PEG) hemoglobin (Hb) developed as an artificial oxygen carrier, which can absorb free NO and translocate NO to a sulfhydryl (SH) moiety, on ischemic cerebral dysfunct …
The aim of the present study was to elucidate the effects of S-nitrosylated (SNO) polyethylene glycol-conjugated (PEG) hemoglobin (Hb) devel …
Long-term blockade of nitric oxide synthesis in rats modulates coronary capillary network remodeling.
Goto D, Fujii S, Zaman AK, Sakuma I, Gao M, Koyama T, Mitchell J, Woodcock-Mitchell J, Sobel BE, Kitabatake A. Goto D, et al. Among authors: kitabatake a. Angiogenesis. 1999;3(2):137-46. doi: 10.1023/a:1009050131966. Angiogenesis. 1999. PMID: 14517431
Long-term blockade of nitric oxide synthesis with N(omega)-nitro-L-arginine methyl ester (L-NAME) induces cardiac perivascular fibrosis in rats. ...
Long-term blockade of nitric oxide synthesis with N(omega)-nitro-L-arginine methyl ester (L-NAME) induces cardiac perivascular fibros …
Beneficial effect of myocardial angiogenesis on cardiac remodeling process by amlodipine and MCI-154.
Kumamoto H, Okamoto H, Watanabe M, Onozuka H, Yoneya K, Nakagawa I, Chiba S, Watanabe S, Mikami T, Abe K, Kitabatake A. Kumamoto H, et al. Among authors: kitabatake a. Am J Physiol. 1999 Apr;276(4):H1117-23. doi: 10.1152/ajpheart.1999.276.4.H1117. Am J Physiol. 1999. PMID: 10199832
The present study examined the effect of long-term treatment with amlodipine and MCI-154 (a Ca2+ sensitizer) on progressive cardiac dysfunction and microvasculature in the dilated cardiomyopathic (DCM) hamster heart. ...
The present study examined the effect of long-term treatment with amlodipine and MCI-154 (a Ca2+ sensitizer) on progressive cardiac d …
17 results