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International Consensus Criteria for Pediatric Sepsis and Septic Shock.
Schlapbach LJ, Watson RS, Sorce LR, Argent AC, Menon K, Hall MW, Akech S, Albers DJ, Alpern ER, Balamuth F, Bembea M, Biban P, Carrol ED, Chiotos K, Chisti MJ, DeWitt PE, Evans I, Flauzino de Oliveira C, Horvat CM, Inwald D, Ishimine P, Jaramillo-Bustamante JC, Levin M, Lodha R, Martin B, Nadel S, Nakagawa S, Peters MJ, Randolph AG, Ranjit S, Rebull MN, Russell S, Scott HF, de Souza DC, Tissieres P, Weiss SL, Wiens MO, Wynn JL, Kissoon N, Zimmerman JJ, Sanchez-Pinto LN, Bennett TD; Society of Critical Care Medicine Pediatric Sepsis Definition Task Force. Schlapbach LJ, et al. Among authors: kissoon n. JAMA. 2024 Feb 27;331(8):665-674. doi: 10.1001/jama.2024.0179. JAMA. 2024. PMID: 38245889
FINDINGS: Based on survey data, most pediatric clinicians used sepsis to refer to infection with life-threatening organ dysfunction, which differed from prior pediatric sepsis criteria that used systemic inflammatory response syndrome (SIRS) criteria, which have poor predictive p …
FINDINGS: Based on survey data, most pediatric clinicians used sepsis to refer to infection with life-threatening organ dysfunction, which d …
Surviving Sepsis Campaign Research Priorities 2023.
De Backer D, Deutschman CS, Hellman J, Myatra SN, Ostermann M, Prescott HC, Talmor D, Antonelli M, Pontes Azevedo LC, Bauer SR, Kissoon N, Loeches IM, Nunnally M, Tissieres P, Vieillard-Baron A, Coopersmith CM; Surviving Sepsis Campaign Research Committee. De Backer D, et al. Among authors: kissoon n. Crit Care Med. 2024 Feb 1;52(2):268-296. doi: 10.1097/CCM.0000000000006135. Epub 2024 Jan 19. Crit Care Med. 2024. PMID: 38240508
CONCLUSIONS: Knowledge advances in multiple clinical domains have been incorporated in progressive iterations of the Surviving Sepsis Campaign guidelines, allowing for evidence-based recommendations for short- and long-term management of sepsis. However, the strength of ex …
CONCLUSIONS: Knowledge advances in multiple clinical domains have been incorporated in progressive iterations of the Surviving Sepsis Campai …
Clinical and imaging outcomes of 100 patients with cerebrospinal fluid-venous fistulas treated by transvenous embolization.
Brinjikji W, Madhavan A, Garza I, Whealy M, Kissoon N, Mark I, Morris PP, Verdoorn J, Benson J, Atkinson JLD, Kobeissi H, Cutsforth-Gregory JK. Brinjikji W, et al. Among authors: kissoon n. J Neurointerv Surg. 2023 Oct 28:jnis-2023-021012. doi: 10.1136/jnis-2023-021012. Online ahead of print. J Neurointerv Surg. 2023. PMID: 37898553
METHODS: Baseline clinical characteristics, imaging findings (including Bern SIH score), technical outcomes, and long-term imaging and clinical outcomes were collected. All patients had at least 3 months of clinical follow-up and had baseline MRI. 99/100 patients underwent …
METHODS: Baseline clinical characteristics, imaging findings (including Bern SIH score), technical outcomes, and long-term imaging an …
Long term outcomes of occipital nerve stimulation.
Montenegro MM, Kissoon NR. Montenegro MM, et al. Among authors: kissoon nr. Front Pain Res (Lausanne). 2023 Mar 20;4:1054764. doi: 10.3389/fpain.2023.1054764. eCollection 2023. Front Pain Res (Lausanne). 2023. PMID: 37021077 Free PMC article. Review.
Only 7 studies in total (3 cluster, 1 occipital neuralgia, 1 cervicogenic headache, 1 SUNHA, 1 paroxysmal hemicrania) provided both short-term and long-term responses up to 24 months to ONS. In cluster headache, the majority of patients (64%) were long term r …
Only 7 studies in total (3 cluster, 1 occipital neuralgia, 1 cervicogenic headache, 1 SUNHA, 1 paroxysmal hemicrania) provided both short- …
Narrative review of peripheral nerve blocks for the management of headache.
Stern JI, Chiang CC, Kissoon NR, Robertson CE. Stern JI, et al. Among authors: kissoon nr. Headache. 2022 Oct;62(9):1077-1092. doi: 10.1111/head.14385. Headache. 2022. PMID: 36286600 Review.
Additional prospective studies are needed to investigate the efficacy and safety of occipital nerve blocks for long-term migraine prevention, as well as for other headache disorders, such as occipital neuralgia....
Additional prospective studies are needed to investigate the efficacy and safety of occipital nerve blocks for long-term migraine pre …
The Current and Future State of Pediatric Sepsis Definitions: An International Survey.
Morin L, Hall M, de Souza D, Guoping L, Jabornisky R, Shime N, Ranjit S, Gilholm P, Nakagawa S, Zimmerman JJ, Sorce LR, Argent A, Kissoon N, Tissières P, Watson RS, Schlapbach LJ; Pediatric Sepsis Definition Taskforce. Morin L, et al. Among authors: kissoon n. Pediatrics. 2022 Jun 1;149(6):e2021052565. doi: 10.1542/peds.2021-052565. Pediatrics. 2022. PMID: 35611643
The World Health Organization definitions were perceived as least useful across all domains. Seventy one percent of respondents agreed that the term sepsis should be restricted to children with infection-associated organ dysfunction. ...
The World Health Organization definitions were perceived as least useful across all domains. Seventy one percent of respondents agreed that …
Refining the Pediatric Multiple Organ Dysfunction Syndrome.
Weiss SL, Carcillo JA, Leclerc F, Leteurtre S, Schlapbach LJ, Tissieres P, Wynn JL, Lacroix J; Pediatric Organ Dysfunction Information Update Mandate (PODIUM) Collaborative. Weiss SL, et al. Pediatrics. 2022 Jan 1;149(1 Suppl 1):S13-S22. doi: 10.1542/peds.2021-052888C. Pediatrics. 2022. PMID: 34970671 Free PMC article.
Since its introduction into the medical literature in the 1970s, the term multiple organ dysfunction syndrome (or some variant) has been applied broadly to any patient with >1 concurrent organ dysfunction. However, the epidemiology, mechanisms, time course, and outcomes …
Since its introduction into the medical literature in the 1970s, the term multiple organ dysfunction syndrome (or some variant) has b …
White Paper on Early Critical Care Services in Low Resource Settings.
Losonczy LI, Papali A, Kivlehan S, Calvello Hynes EJ, Calderon G, Laytin A, Moll V, Al Hazmi A, Alsabri M, Aryal D, Atua V, Becker T, Benzoni N, Dippenaar E, Duneant E, Girma B, George N, Gupta P, Jaung M, Hollong B, Kabongo D, Kruisselbrink RJ, Lee D, Maldonado A, May J, Osei-Ampofo M, Osman YO, Owoo C, Rouhani SA, Sawe H, Schnorr D, Shrestha GS, Sohoni A, Sultan M, Tenner AG, Yusuf H, Adhikari NK, Murthy S, Kissoon N, Marshall J, Khoury A, Bellou A, Wallis L, Reynolds T. Losonczy LI, et al. Among authors: kissoon n. Ann Glob Health. 2021 Nov 3;87(1):105. doi: 10.5334/aogh.3377. eCollection 2021. Ann Glob Health. 2021. PMID: 34786353 Free PMC article.
Education initiatives for physicians, nurses, and allied health staff that focus on protocolized emergency response training can bridge the workforce gap in the short-term; however, each country's current human resources must be evaluated to decide on the duration of train …
Education initiatives for physicians, nurses, and allied health staff that focus on protocolized emergency response training can bridge the …
Challenges in pediatric post-sepsis care in resource limited settings: a narrative review.
Wiens MO, Kissoon N, Holsti L. Wiens MO, et al. Among authors: kissoon n. Transl Pediatr. 2021 Oct;10(10):2666-2677. doi: 10.21037/tp-20-390. Transl Pediatr. 2021. PMID: 34765492 Free PMC article. Review.
Data is presented within three sections. The first two sections on the short and long-term outcomes among sepsis survivors each outline the epidemiology as well as review relevant interventional research done. ...While long-term outcomes have not been well character …
Data is presented within three sections. The first two sections on the short and long-term outcomes among sepsis survivors each outli …
Effects of oral anticoagulation for atrial fibrillation after spontaneous intracranial haemorrhage in the UK: a randomised, open-label, assessor-masked, pilot-phase, non-inferiority trial.
SoSTART Collaboration. SoSTART Collaboration. Lancet Neurol. 2021 Oct;20(10):842-853. doi: 10.1016/S1474-4422(21)00264-7. Epub 2021 Sep 3. Lancet Neurol. 2021. PMID: 34487722
Web-based computerised randomisation incorporating a minimisation algorithm allocated participants (1:1) to start or avoid long-term (1 year) full treatment dose open-label oral anticoagulation. ...
Web-based computerised randomisation incorporating a minimisation algorithm allocated participants (1:1) to start or avoid long-term …
25 results