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Preventive service utilization among adults with cystic fibrosis covered by private insurance is comparable to the general population.
Malhotra S, Hyer JM, Dalmacy D, Hayes D Jr, Tumin D, Kirkby SE, Jonas DE, Bose-Brill S, Li SS. Malhotra S, et al. Among authors: kirkby se. J Cyst Fibros. 2024 Jan 13:S1569-1993(23)01698-3. doi: 10.1016/j.jcf.2023.11.013. Online ahead of print. J Cyst Fibros. 2024. PMID: 38220475
BACKGROUND: As the life expectancy of the cystic fibrosis (CF) population is lengthening with modulator therapies, diligent age-appropriate screening and preventive care are increasingly vital for long-term health and wellbeing. METHODS: We performed a retrospective analys …
BACKGROUND: As the life expectancy of the cystic fibrosis (CF) population is lengthening with modulator therapies, diligent age-appropriate …
Long-Term Survival Following Primary Graft Dysfunction Development in Lung Transplantation.
Gouchoe DA, Whitson BA, Rosenheck J, Henn MC, Mokadam NA, Ramsammy V, Kirkby S, Nunley D, Ganapathi AM. Gouchoe DA, et al. Among authors: kirkby s. J Surg Res. 2024 Apr;296:47-55. doi: 10.1016/j.jss.2023.12.006. Epub 2024 Jan 13. J Surg Res. 2024. PMID: 38219506
INTRODUCTION: Primary graft dysfunction (PGD) is a known risk factor for early mortality following lung transplant (LT). However, the outcomes of patients who achieve long-term survival following index hospitalization are unknown. We aimed to determine the long-term
INTRODUCTION: Primary graft dysfunction (PGD) is a known risk factor for early mortality following lung transplant (LT). However, the outcom …
Lung transplantation in the septuagenarian can be successfully performed though long-term results impacted by diseases of aging.
Benissan-Messan DZ, Ganapathi AM, Guo M, Henn MC, Keller BC, Howsare M, Rosenheck JP, Kirkby SE, Mokadam NA, Nunley D, Whitson BA. Benissan-Messan DZ, et al. Among authors: kirkby se. Clin Transplant. 2022 May;36(5):e14593. doi: 10.1111/ctr.14593. Epub 2022 Jan 27. Clin Transplant. 2022. PMID: 35032351
BACKGROUND: Advanced age is considered a risk factor for lung transplantation (LTX). We sought to evaluate the long-term outcomes of LTX in the septuagenarian. METHODS: LTX recipients in the UNOS transplant registry (May 1, 2005-June 12, 2020) were stratified into 18-59, 6 …
BACKGROUND: Advanced age is considered a risk factor for lung transplantation (LTX). We sought to evaluate the long-term outcomes of …
Lung Transplant Index: A Quality Improvement Initiative.
Hayes D Jr, Feeney B, O'Connor DJ, Nicholson KL, Nance AE, Sakellaris KK, Dempster NR, Groh JD, Kirkby SE. Hayes D Jr, et al. Among authors: kirkby se. Pediatr Qual Saf. 2019 Sep 19;4(5):e209. doi: 10.1097/pq9.0000000000000209. eCollection 2019 Sep-Oct. Pediatr Qual Saf. 2019. PMID: 31745512 Free PMC article.
Limited long-term survival is a recognized problem in adolescent/young adult lung transplant recipients. ...
Limited long-term survival is a recognized problem in adolescent/young adult lung transplant recipients. ...
Risks associated with lung transplantation in cystic fibrosis patients.
Li SS, Tumin D, Krone KA, Boyer D, Kirkby SE, Mansour HM, Hayes D Jr. Li SS, et al. Among authors: kirkby se. Expert Rev Respir Med. 2018 Nov;12(11):893-904. doi: 10.1080/17476348.2018.1522254. Epub 2018 Sep 21. Expert Rev Respir Med. 2018. PMID: 30198350 Review.
Evolving surgical techniques, therapeutics, and perioperative management have improved short-term survival after lung transplantation, yet have not translated into significant improvement in long-term mortality. ...Ongoing prospective studies should be reserved for …
Evolving surgical techniques, therapeutics, and perioperative management have improved short-term survival after lung transplantation …
Chronic opioid use and clinical outcomes in lung transplant recipients: A single-center cohort study.
Drees D, Tumin D, Miller R, Kirkby S, Bhalla T, Tobias JD, Hayes D Jr. Drees D, et al. Among authors: kirkby s. Clin Respir J. 2018 Sep;12(9):2446-2453. doi: 10.1111/crj.12948. Clin Respir J. 2018. PMID: 30054981
However, little is known about possible influences of chronic opioid use on outcomes of lung transplantation (LTx). OBJECTIVES: We assessed whether long-term chronic opioid use influenced clinical outcomes among LTx recipients at our program. ...
However, little is known about possible influences of chronic opioid use on outcomes of lung transplantation (LTx). OBJECTIVES: We assessed …
The expression of Mirc1/Mir17-92 cluster in sputum samples correlates with pulmonary exacerbations in cystic fibrosis patients.
Krause K, Kopp BT, Tazi MF, Caution K, Hamilton K, Badr A, Shrestha C, Tumin D, Hayes D Jr, Robledo-Avila F, Hall-Stoodley L, Klamer BG, Zhang X, Partida-Sanchez S, Parinandi NL, Kirkby SE, Dakhlallah D, McCoy KS, Cormet-Boyaka E, Amer AO. Krause K, et al. Among authors: kirkby se. J Cyst Fibros. 2018 Jul;17(4):454-461. doi: 10.1016/j.jcf.2017.11.005. Epub 2017 Dec 11. J Cyst Fibros. 2018. PMID: 29241629 Free PMC article.
Many patients with CF suffer from repeated pulmonary exacerbations that are predictors of worsened long-term morbidity and mortality. There are no reliable markers that associate with the onset or progression of an exacerbation or pulmonary deterioration. ...
Many patients with CF suffer from repeated pulmonary exacerbations that are predictors of worsened long-term morbidity and mortality. …
Influence of graft ischemic time on survival in children with cystic fibrosis after lung transplantation.
Hayes D Jr, Tumin D, Kopp BT, Tobias JD, Sheikh SI, Kirkby SE. Hayes D Jr, et al. Among authors: kirkby se. Pediatr Pulmonol. 2016 Sep;51(9):908-13. doi: 10.1002/ppul.23432. Epub 2016 Apr 29. Pediatr Pulmonol. 2016. PMID: 27129023
CONCLUSIONS: Ischemic time of 4-6 hr was associated with the highest long-term survival in first-time pediatric LTx recipients with CF, with ischemic time <4 hr related to diminished survival. ...
CONCLUSIONS: Ischemic time of 4-6 hr was associated with the highest long-term survival in first-time pediatric LTx recipients with C …
Pulmonary Artery Pressure and Benefit of Lung Transplantation in Adult Cystic Fibrosis Patients.
Hayes D Jr, Tumin D, Daniels CJ, McCoy KS, Mansour HM, Tobias JD, Kirkby SE. Hayes D Jr, et al. Among authors: kirkby se. Ann Thorac Surg. 2016 Mar;101(3):1104-9. doi: 10.1016/j.athoracsur.2015.09.086. Epub 2015 Dec 11. Ann Thorac Surg. 2016. PMID: 26687141
A multivariate Cox model of survival since list entry including 1,336 patients found a protective but statistically insignificant benefit of LTx for patients whose MPAP at listing was 25 mm Hg (HR, 0.879; 95% confidence interval [CI], 0.657-1.177; p = 0.388), yet LTx was predicte …
A multivariate Cox model of survival since list entry including 1,336 patients found a protective but statistically insignificant benefit of …
To induce or not to induce: a 21st century evaluation of lung transplant immunosuppression's effect on survival.
Whitson BA, Lehman A, Wehr A, Hayes D Jr, Kirkby S, Pope-Harman A, Kilic A, Higgins RS. Whitson BA, et al. Among authors: kirkby s. Clin Transplant. 2014 Apr;28(4):450-61. doi: 10.1111/ctr.12339. Clin Transplant. 2014. PMID: 24750290
INTRODUCTION: The impact of induction immunosuppression on long-term survival in lung transplant recipients remains unclear. We sought to evaluate the effect of contemporary induction immunosuppression agents in lung transplant recipients' survival, utilizing national regi …
INTRODUCTION: The impact of induction immunosuppression on long-term survival in lung transplant recipients remains unclear. We sough …
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