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Coxsackievirus infection induces autophagy-like vesicles and megaphagosomes in pancreatic acinar cells in vivo.
Kemball CC, Alirezaei M, Flynn CT, Wood MR, Harkins S, Kiosses WB, Whitton JL. Kemball CC, et al. Among authors: kiosses wb. J Virol. 2010 Dec;84(23):12110-24. doi: 10.1128/JVI.01417-10. Epub 2010 Sep 22. J Virol. 2010. PMID: 20861268 Free PMC article.
However, the virus markedly, albeit incompletely, limits the fusion of autophagosomes (and/or amphisomes) with lysosomes, and, perhaps as a result, very large autophagy-related structures are formed within infected cells; we term these structures megaphagosomes. Ultrastruc …
However, the virus markedly, albeit incompletely, limits the fusion of autophagosomes (and/or amphisomes) with lysosomes, and, perhaps as a …
Short-term fasting induces profound neuronal autophagy.
Alirezaei M, Kemball CC, Flynn CT, Wood MR, Whitton JL, Kiosses WB. Alirezaei M, et al. Among authors: kiosses wb. Autophagy. 2010 Aug;6(6):702-10. doi: 10.4161/auto.6.6.12376. Epub 2010 Aug 14. Autophagy. 2010. PMID: 20534972 Free PMC article.
We use the method to identify constitutive autophagosomes in cortical neurons and Purkinje cells, and we show that short-term fasting leads to a dramatic upregulation in neuronal autophagy. ...
We use the method to identify constitutive autophagosomes in cortical neurons and Purkinje cells, and we show that short-term fasting …
Viral persistence and chronic immunopathology in the adult central nervous system following Coxsackievirus infection during the neonatal period.
Feuer R, Ruller CM, An N, Tabor-Godwin JM, Rhoades RE, Maciejewski S, Pagarigan RR, Cornell CT, Crocker SJ, Kiosses WB, Pham-Mitchell N, Campbell IL, Whitton JL. Feuer R, et al. Among authors: kiosses wb. J Virol. 2009 Sep;83(18):9356-69. doi: 10.1128/JVI.02382-07. Epub 2009 Jul 1. J Virol. 2009. PMID: 19570873 Free PMC article.
Despite the extreme susceptibility of newborn infants to coxsackievirus infection and viral tropism for the CNS, few studies have been aimed at determining the long-term consequences of infection on the developing CNS. We previously described a neonatal mouse model of coxs …
Despite the extreme susceptibility of newborn infants to coxsackievirus infection and viral tropism for the CNS, few studies have been aimed …