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Serial Biomarkers of De Novo Lipogenesis Fatty Acids and Incident Heart Failure in Older Adults: The Cardiovascular Health Study.
Lee Y, Lai HTM, de Oliveira Otto MC, Lemaitre RN, McKnight B, King IB, Song X, Huggins GS, Vest AR, Siscovick DS, Mozaffarian D. Lee Y, et al. Among authors: king ib. J Am Heart Assoc. 2020 Feb 18;9(4):e014119. doi: 10.1161/JAHA.119.014119. Epub 2020 Feb 5. J Am Heart Assoc. 2020. PMID: 32020839 Free PMC article.
Although elevated DNL is linked to several metabolic abnormalities, little is known about how long-term habitual levels and changes in levels of FAs in the DNL pathway relate to incident heart failure (HF). ...We prospectively evaluated associations with HF risk of (1) hab …
Although elevated DNL is linked to several metabolic abnormalities, little is known about how long-term habitual levels and changes i …
Serial Plasma Phospholipid Fatty Acids in the De Novo Lipogenesis Pathway and Total Mortality, Cause-Specific Mortality, and Cardiovascular Diseases in the Cardiovascular Health Study.
Lai HTM, de Oliveira Otto MC, Lee Y, Wu JHY, Song X, King IB, Psaty BM, Lemaitre RN, McKnight B, Siscovick DS, Mozaffarian D. Lai HTM, et al. Among authors: king ib. J Am Heart Assoc. 2019 Nov 19;8(22):e012881. doi: 10.1161/JAHA.119.012881. Epub 2019 Nov 12. J Am Heart Assoc. 2019. PMID: 31711385 Free PMC article.
Changes in levels of 16:0 were positively, and 18:0 inversely, associated with all-cause mortality (hazard ratio=1.23, 95% CI=1.08-1.41; and hazard ratio=0.78, 95% CI=0.68-0.90). Conclusions Higher long-term levels of 16:0, 16:1n-7, and 18:1n-9 and changes in 16:0 were pos …
Changes in levels of 16:0 were positively, and 18:0 inversely, associated with all-cause mortality (hazard ratio=1.23, 95% CI=1.08-1.41; and …
Serial measures of circulating biomarkers of dairy fat and total and cause-specific mortality in older adults: the Cardiovascular Health Study.
de Oliveira Otto MC, Lemaitre RN, Song X, King IB, Siscovick DS, Mozaffarian D. de Oliveira Otto MC, et al. Among authors: king ib. Am J Clin Nutr. 2018 Sep 1;108(3):476-484. doi: 10.1093/ajcn/nqy117. Am J Clin Nutr. 2018. PMID: 30007304 Free PMC article.
BACKGROUND: Controversy has emerged about the benefits compared with harms of dairy fat, including concerns over long-term effects. Previous observational studies have assessed self-reported estimates of consumption or a single biomarker measure at baseline, which may lead …
BACKGROUND: Controversy has emerged about the benefits compared with harms of dairy fat, including concerns over long-term effects. P …
Variable penetrance of metabolic phenotypes and development of high-fat diet-induced adiposity in NEIL1-deficient mice.
Sampath H, Batra AK, Vartanian V, Carmical JR, Prusak D, King IB, Lowell B, Earley LF, Wood TG, Marks DL, McCullough AK, R Stephen L. Sampath H, et al. Among authors: king ib. Am J Physiol Endocrinol Metab. 2011 Apr;300(4):E724-34. doi: 10.1152/ajpendo.00387.2010. Epub 2011 Feb 1. Am J Physiol Endocrinol Metab. 2011. PMID: 21285402 Free PMC article.
Additionally, hepatic expression of several inflammatory genes was significantly upregulated in neil1(-/-) mice following high-fat diet challenge compared with chow-fed or neil1(+/+) counterparts. A long-term high-fat diet also induced glucose intolerance as well as a sign …
Additionally, hepatic expression of several inflammatory genes was significantly upregulated in neil1(-/-) mice following high-fat diet chal …
Serum beta-glucuronidase activity in response to fruit and vegetable supplementation: a controlled feeding study.
Maruti SS, Chang JL, Prunty JA, Bigler J, Schwarz Y, Li SS, Li L, King IB, Potter JD, Lampe JW. Maruti SS, et al. Among authors: king ib. Cancer Epidemiol Biomarkers Prev. 2008 Jul;17(7):1808-12. doi: 10.1158/1055-9965.EPI-07-2660. Cancer Epidemiol Biomarkers Prev. 2008. PMID: 18628435 Free PMC article. Clinical Trial.
Response to the experimental diet did not differ by sex (P(interaction) = 0.30), but there was a suggestion of a short-term diet effect at 8 versus 15 days (P(interaction) = 0.06). CONCLUSION: This intervention of selected F&V did not lower beta-glucuronidase activity. …
Response to the experimental diet did not differ by sex (P(interaction) = 0.30), but there was a suggestion of a short-term diet effe …
Maternal second-trimester serum ferritin concentrations and subsequent risk of preterm delivery.
Xiao R, Sorensen TK, Frederick IO, El-Bastawissi A, King IB, Leisenring WM, Williams MA. Xiao R, et al. Among authors: king ib. Paediatr Perinat Epidemiol. 2002 Oct;16(4):297-304. doi: 10.1046/j.1365-3016.2002.00448.x. Paediatr Perinat Epidemiol. 2002. PMID: 12445145
The 312 preterm delivery cases, studied in aggregate and in subgroups [spontaneous preterm labour, preterm premature rupture of membranes, medically induced preterm delivery, moderate preterm delivery (gestational age at delivery 34-36 weeks) and very preterm delivery (gestationa …
The 312 preterm delivery cases, studied in aggregate and in subgroups [spontaneous preterm labour, preterm premature rupture of membranes, m …