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High frequency of circulating non-classical monocytes is associated with stable remission in relapsing-remitting multiple sclerosis.
Minote M, Sato W, Kimura K, Kimura A, Lin Y, Okamoto T, Takahashi R, Yamamura T. Minote M, et al. Among authors: kimura a. Immunol Med. 2024 Mar 27:1-15. doi: 10.1080/25785826.2024.2331271. Online ahead of print. Immunol Med. 2024. PMID: 38539051
Patients showing long-term NEDA (n = 31) had significantly higher frequencies of non-classical monocytes (NCMs) (6.1% vs 1.4%) and activated regulatory T cells (Tregs; 2.1% vs 1.6%) than those with evidence of disease activity (n = 8). ...In addition, the NCM frequency and …
Patients showing long-term NEDA (n = 31) had significantly higher frequencies of non-classical monocytes (NCMs) (6.1% vs 1.4%) and ac …
A retrospective clinical practice study comparing the usefulness of dual-orexin receptor antagonists and a melatonin receptor agonist in patients switching from long-term benzodiazepine receptor agonists.
Tachibana M, Kanahara N, Oda Y, Hasegawa T, Kimura A, Iyo M. Tachibana M, et al. Among authors: kimura a. J Clin Sleep Med. 2024 Apr 1;20(4):603-613. doi: 10.5664/jcsm.10946. J Clin Sleep Med. 2024. PMID: 38063235
A retrospective clinical practice study comparing the usefulness of dual-orexin receptor antagonists and a melatonin receptor agonist in patients switching from long-term benzodiazepine receptor agonists. J Clin Sleep Med. 2024;20(4):603-613....
A retrospective clinical practice study comparing the usefulness of dual-orexin receptor antagonists and a melatonin receptor agonist in pat …
Genetics of chilling response at early growth stage in rice: a recessive gene for tolerance and importance of acclimation.
Baruah AR, Bannai H, Meija Y, Kimura A, Ueno H, Koide Y, Kishima Y, Palta J, Kasuga J, Yamamoto MP, Onishi K. Baruah AR, et al. Among authors: kimura a. AoB Plants. 2023 Nov 8;15(6):plad075. doi: 10.1093/aobpla/plad075. eCollection 2023 Dec. AoB Plants. 2023. PMID: 38028749 Free PMC article.
Chilling acclimation treatments at a wide range of temperatures (8 C-16 C) for 72 h concealed the susceptible phenotype of Ctp-1(W107) and Ctp-1(HY). Furthermore, short-term acclimation treatment of 12 h at 8 C was enough to be fully acclimated. ...
Chilling acclimation treatments at a wide range of temperatures (8 C-16 C) for 72 h concealed the susceptible phenotype of Ctp-1(W107) and C …
Long-term Effects of IL-6 Receptor Blockade Therapy on Regulatory Lymphocytes and Neutrophils in Neuromyelitis Optica Spectrum Disorder.
Matsuoka T, Araki M, Lin Y, Okamoto T, Gold R, Chihara N, Sato W, Kimura A, Tachimori H, Miyamoto K, Kusunoki S, Yamamura T. Matsuoka T, et al. Among authors: kimura a. Neurol Neuroimmunol Neuroinflamm. 2023 Oct 20;11(1):e200173. doi: 10.1212/NXI.0000000000200173. Print 2024 Jan. Neurol Neuroimmunol Neuroinflamm. 2023. PMID: 37863660 Free PMC article.
Anti-IL-6 receptor (IL-6R) therapy prevents relapses in patients with anti-aquaporin 4 (AQP4)-IgG-positive NMOSD; however, it remains unclear how cellular immune components are altered by anti-IL-6R therapy. In this study, we examined the long-term effects of the anti-IL-6 …
Anti-IL-6 receptor (IL-6R) therapy prevents relapses in patients with anti-aquaporin 4 (AQP4)-IgG-positive NMOSD; however, it remains unclea …
Effects of Short-term Electronic(e)-Cigarette Aerosol Exposure in the Mouse Larynx.
Easwaran M, Maria CS, Martinez JD, Hung B, Yu X, Soo J, Kimura A, Gross ER, Erickson-DiRenzo E. Easwaran M, et al. Among authors: kimura a. Laryngoscope. 2024 Mar;134(3):1316-1326. doi: 10.1002/lary.31043. Epub 2023 Sep 12. Laryngoscope. 2024. PMID: 37698394
VF macrophage and T-cell levels slightly increased after 10 days of JMi exposures. CONCLUSIONS: Short-term e-cigarette exposures cause minimal flavor- and region-specific cellular and inflammatory changes in the mouse larynx. This work provides a foundation for long-ter …
VF macrophage and T-cell levels slightly increased after 10 days of JMi exposures. CONCLUSIONS: Short-term e-cigarette exposures caus …
Predicting conversion surgery in patients with locally advanced pancreatic cancer after modified FOLFIRINOX treatment.
Ninomiya R, Abe S, Chiyoda T, Kogure R, Kimura A, Komagome M, Maki A, Beck Y. Ninomiya R, et al. Among authors: kimura a. Asian J Surg. 2023 Sep;46(9):3542-3548. doi: 10.1016/j.asjsur.2023.03.162. Epub 2023 Apr 20. Asian J Surg. 2023. PMID: 37087347 Free article.

All of the patients in the CS group fell into the 2-3 category, compared with 2 of 23 patients in the non-CS group (P < 0.001). CONCLUSION: CS after FFX contributes to the long-term survival of patients with LAPC. The CS score could be an indicator for transition to CS.

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All of the patients in the CS group fell into the 2-3 category, compared with 2 of 23 patients in the non-CS group (P < 0.001). CONCLUSIO

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Geriatric nutritional risk index as the prognostic factor in older patients with fragility hip fractures.
Tsutsui T, Fujiwara T, Matsumoto Y, Kimura A, Kanahori M, Arisumi S, Oyamada A, Ohishi M, Ikuta K, Tsuchiya K, Tayama N, Tomari S, Miyahara H, Mae T, Hara T, Saito T, Arizono T, Kaji K, Mawatari T, Fujiwara M, Takasaki M, Shin K, Ninomiya K, Nakaie K, Antoku Y, Iwamoto Y, Nakashima Y. Tsutsui T, et al. Among authors: kimura a. Osteoporos Int. 2023 Jul;34(7):1207-1221. doi: 10.1007/s00198-023-06753-3. Epub 2023 Apr 17. Osteoporos Int. 2023. PMID: 37067545
This study investigated the long-term survival and incidence of secondary fractures after fragility hip fractures. ...BACKGROUND: Malnutrition negatively influences the postoperative survival of patients with fragility hip fractures (FHFs); however, little is known about t …
This study investigated the long-term survival and incidence of secondary fractures after fragility hip fractures. ...BACKGROUND: Mal …
Partial depolymerization of tamarind seed xyloglucan and its functionality toward enhancing the solubility of curcumin.
Lang W, Tagami T, Kang HJ, Okuyama M, Sakairi N, Kimura A. Lang W, et al. Among authors: kimura a. Carbohydr Polym. 2023 May 1;307:120629. doi: 10.1016/j.carbpol.2023.120629. Epub 2023 Jan 30. Carbohydr Polym. 2023. PMID: 36781280
We prepared xyloglucan megalosaccharides (XMSs) by partial depolymerization, where term megalosaccharide (MS) defines the middle chain-length saccharide between DPs 10 and 100. ...
We prepared xyloglucan megalosaccharides (XMSs) by partial depolymerization, where term megalosaccharide (MS) defines the middle chai …
Final efficacy and safety results and biomarker analysis of a phase 2 study of cabozantinib in Japanese patients with advanced renal cell carcinoma.
Nakaigawa N, Tomita Y, Tamada S, Tatsugami K, Osawa T, Oya M, Kanayama H, Miura Y, Sassa N, Nishimura K, Nozawa M, Masumori N, Miyoshi Y, Kuroda S, Kimura A. Nakaigawa N, et al. Among authors: kimura a. Int J Clin Oncol. 2023 Mar;28(3):416-426. doi: 10.1007/s10147-022-02283-w. Epub 2023 Jan 3. Int J Clin Oncol. 2023. PMID: 36595123 Free PMC article. Clinical Trial.
Nonresponders to cabozantinib showed relatively higher HGF levels than responders at baseline. CONCLUSIONS: Updated analyses demonstrate the long-term efficacy and safety of cabozantinib in Japanese patients with advanced RCC after at least one VEGFR-TKI therapy. ...
Nonresponders to cabozantinib showed relatively higher HGF levels than responders at baseline. CONCLUSIONS: Updated analyses demonstrate the …
Clinical Features and Neuroimaging Findings of Neuropil Antibody-Positive Idiopathic Sporadic Ataxia of Unknown Etiology.
Takekoshi A, Kimura A, Yoshikura N, Yamakawa I, Urushitani M, Nakamura K, Yoshida K, Shimohata T. Takekoshi A, et al. Among authors: kimura a. Cerebellum. 2023 Oct;22(5):915-924. doi: 10.1007/s12311-022-01468-3. Epub 2022 Sep 3. Cerebellum. 2023. PMID: 36057079
Idiopathic sporadic ataxia (ISA) is the clinical term for nonfamilial ataxia with adult-onset and a slowly progressive course. ...
Idiopathic sporadic ataxia (ISA) is the clinical term for nonfamilial ataxia with adult-onset and a slowly progressive course. ...
121 results