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Long-term ozone exposure and mortality in patients with chronic kidney disease: a large cohort study.
Kim E, Huh H, Mo Y, Park JY, Jung J, Lee H, Kim S, Kim DK, Kim YS, Lim CS, Lee JP, Kim YC, Kim H. Kim E, et al. Among authors: kim yc. BMC Nephrol. 2024 Feb 28;25(1):74. doi: 10.1186/s12882-024-03500-6. BMC Nephrol. 2024. PMID: 38418953 Free PMC article.
BACKGROUND: Epidemiologic studies on the effects of long-term exposure to ozone (O(3)) have shown inconclusive results. It is unclear whether to O(3) has an effect on chronic kidney disease (CKD). ...The ozone hazard ratio for all-cause mortality was 1.012 (95% confidence …
BACKGROUND: Epidemiologic studies on the effects of long-term exposure to ozone (O(3)) have shown inconclusive results. It is unclear …
Hemi one-piece distraction osteogenesis for unilateral coronal craniosynostosis.
Kim TH, Kim YC, Rah YS, Choi JW. Kim TH, et al. Among authors: kim yc. J Craniomaxillofac Surg. 2024 Feb;52(2):252-259. doi: 10.1016/j.jcms.2023.12.010. Epub 2023 Dec 28. J Craniomaxillofac Surg. 2024. PMID: 38169232
CONCLUSION: This study reveals less invasive, highly effective techniques for craniosynostosis treatment, notably a unilateral osteotomy with distraction method. Nevertheless, to confirm their long-term efficacy and durability, more studies with longer follow-ups are essen …
CONCLUSION: This study reveals less invasive, highly effective techniques for craniosynostosis treatment, notably a unilateral osteotomy wit …
Chlorophyll a and novel synthetic derivatives alleviate atopic dermatitis by suppressing Th2 cell differentiation via IL-4 receptor modulation.
Kang KM, Han JH, Kim KS, Kim EK, Shin Y, Park JH, Kim H, Kim NY, Kim YG, Kim H, Park H, Kim YM, Kee SJ, Kim SJ, Kim HS, Kim YC. Kang KM, et al. Among authors: kim yc. Clin Immunol. 2024 Jan;258:109852. doi: 10.1016/j.clim.2023.109852. Epub 2023 Nov 27. Clin Immunol. 2024. PMID: 38029848
Atopic dermatitis (AD) treatment has largely relied on non-specific broad immunosuppressants despite their long-term toxicities until the approval of dupilumab, which blocks IL-4 signaling to target Th2 cell responses. ...
Atopic dermatitis (AD) treatment has largely relied on non-specific broad immunosuppressants despite their long-term toxicities until …
Tepotinib in patients with non-small cell lung cancer with high-level MET amplification detected by liquid biopsy: VISION Cohort B.
Le X, Paz-Ares LG, Van Meerbeeck J, Viteri S, Galvez CC, Smit EF, Garassino M, Veillon R, Baz DV, Pradera JF, Sereno M, Kozuki T, Kim YC, Yoo SS, Han JY, Kang JH, Son CH, Choi YJ, Stroh C, Juraeva D, Vioix H, Bruns R, Otto G, Johne A, Paik PK. Le X, et al. Among authors: kim yc. Cell Rep Med. 2023 Nov 21;4(11):101280. doi: 10.1016/j.xcrm.2023.101280. Epub 2023 Nov 8. Cell Rep Med. 2023. PMID: 37944528 Free PMC article.
In exploratory biomarker analyses, focal METamp, RB1 wild-type, MYC diploidy, low circulating tumor DNA (ctDNA) burden at baseline, and early molecular response are associated with better outcomes. Adverse events include edema (composite term; any grade: 58.3%; grade 3: 12 …
In exploratory biomarker analyses, focal METamp, RB1 wild-type, MYC diploidy, low circulating tumor DNA (ctDNA) burden at baseline, and earl …
Sparsentan versus Irbesartan in Focal Segmental Glomerulosclerosis.
Rheault MN, Alpers CE, Barratt J, Bieler S, Canetta P, Chae DW, Coppock G, Diva U, Gesualdo L, Heerspink HJL, Inrig JK, Kirsztajn GM, Kohan D, Komers R, Kooienga LA, Lieberman K, Mercer A, Noronha IL, Perkovic V, Radhakrishnan J, Rote W, Rovin B, Tesar V, Trimarchi H, Tumlin J, Wong MG, Trachtman H; DUPRO Steering Committee and DUPLEX Investigators. Rheault MN, et al. N Engl J Med. 2023 Dec 28;389(26):2436-2445. doi: 10.1056/NEJMoa2308550. Epub 2023 Nov 3. N Engl J Med. 2023. PMID: 37921461 Clinical Trial.
In an 8-week, phase 2 trial, sparsentan, a dual endothelin-angiotensin receptor antagonist, reduced proteinuria in patients with FSGS. The efficacy and safety of longer-term treatment with sparsentan for FSGS are unknown. METHODS: In this phase 3 trial, we enrolled patient …
In an 8-week, phase 2 trial, sparsentan, a dual endothelin-angiotensin receptor antagonist, reduced proteinuria in patients with FSGS. The e …
Developing a framework for regular and sustainable qualitative assessment of antibiotic use in Korean medical institutions: a Delphi study.
Park SY, Kim YC, Moon SM, Kim B, Lee R, Kim HB; Korea Study Group for Antimicrobial Stewardship (KOSGAP). Park SY, et al. Among authors: kim yc. Antimicrob Resist Infect Control. 2023 Oct 18;12(1):114. doi: 10.1186/s13756-023-01319-8. Antimicrob Resist Infect Control. 2023. PMID: 37853455 Free PMC article. Review.
RESULTS: The response rate for all three surveys was 95% (19/20), while the panel meeting attendance rate was 90% (18/20). The following long-term goals were defined to assess the annual use of antibacterial and antifungal agents in all medical institutions, including clin …
RESULTS: The response rate for all three surveys was 95% (19/20), while the panel meeting attendance rate was 90% (18/20). The following lon …
Primary sclerosing cholangitis causally affects kidney function decline: A Mendelian randomization study.
Cho JM, Koh JH, Kim SG, Lee S, Kim Y, Cho S, Kim K, Kim YC, Han SS, Lee H, Lee JP, Joo KW, Lim CS, Kim YS, Kim DK, Park S. Cho JM, et al. Among authors: kim yc. J Gastroenterol Hepatol. 2024 Jan;39(1):185-192. doi: 10.1111/jgh.16355. Epub 2023 Sep 19. J Gastroenterol Hepatol. 2024. PMID: 37726875
BACKGROUND AND AIM: The causal linkage between primary sclerosing cholangitis (PSC) and kidney function is unexplored despite their potential for long-term detrimental effects on kidney function. METHODS: Two-sample summary-level Mendelian randomization (MR) study was cond …
BACKGROUND AND AIM: The causal linkage between primary sclerosing cholangitis (PSC) and kidney function is unexplored despite their potentia …
Causal effects from tobacco smoking initiation on obesity-related traits: a Mendelian randomization study.
Park S, Kim SG, Lee S, Kim Y, Cho S, Kim K, Kim YC, Han SS, Lee H, Lee JP, Joo KW, Lim CS, Kim YS, Kim DK. Park S, et al. Among authors: kim yc. Int J Obes (Lond). 2023 Dec;47(12):1232-1238. doi: 10.1038/s41366-023-01371-9. Epub 2023 Aug 26. Int J Obes (Lond). 2023. PMID: 37634025
CONCLUSION: Tobacco initiation may lead to worse obesity-related traits in the general 40- to 69-year-old individuals. Therefore, tobacco-use initiation as a long-term weight-control measure should be discouraged....
CONCLUSION: Tobacco initiation may lead to worse obesity-related traits in the general 40- to 69-year-old individuals. Therefore, tobacco-us …
Causal Effect of Chondroitin, Glucosamine, Vitamin, and Mineral Intake on Kidney Function: A Mendelian Randomization Study.
Cho JM, Koh JH, Kim SG, Lee S, Kim Y, Cho S, Kim K, Kim YC, Han SS, Lee H, Lee JP, Joo KW, Lim CS, Kim YS, Kim DK, Park S. Cho JM, et al. Among authors: kim yc. Nutrients. 2023 Jul 26;15(15):3318. doi: 10.3390/nu15153318. Nutrients. 2023. PMID: 37571255 Free PMC article.
Our MR study suggests a potential causal effect of chondroitin and glucosamine intake on kidney function. Therefore, clinicians should carefully monitor their long-term effects....
Our MR study suggests a potential causal effect of chondroitin and glucosamine intake on kidney function. Therefore, clinicians should caref …
Immune Response Kinetics Following a Third Heterologous BNT162b2 Booster Dose After Primary 2-Dose ChAdOx1 Vaccination in Relation to Omicron Breakthrough Infection: A Prospective Nationwide Cohort Study in South Korea.
Ahn JY, Ko JH, Peck KR, Bae S, Kim SH, Lee KH, Song YG, Kim YC, Park YS, Song KH, Kim ES, Jeong HW, Kim SW, Kwon KT, Choi WS, Choi JY. Ahn JY, et al. Among authors: kim yc. Open Forum Infect Dis. 2023 Jul 13;10(7):ofad363. doi: 10.1093/ofid/ofad363. eCollection 2023 Jul. Open Forum Infect Dis. 2023. PMID: 37520424 Free PMC article.
BACKGROUND: Immune responses to each vaccine must be investigated to establish effective vaccination strategies for the ongoing coronavirus disease (COVID-19) pandemic. We investigated the long-term kinetics of immune responses after heterologous booster vaccination in rel …
BACKGROUND: Immune responses to each vaccine must be investigated to establish effective vaccination strategies for the ongoing coronavirus …
115 results