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The localized inflammatory response to bronchoscopic thermal vapor ablation.
Gompelmann D, Eberhardt R, Ernst A, Hopkins P, Egan J, Stanzel F, Valipour A, Wagner M, Witt C, Baker KM, Gotfried MH, Kesten S, Snell G, Herth FJ. Gompelmann D, et al. Among authors: kesten s. Respiration. 2013;86(4):324-31. doi: 10.1159/000354175. Epub 2013 Aug 23. Respiration. 2013. PMID: 23988888 Free article.
The clinical manifestations of the LIR are predictive of long-term clinical benefits....
The clinical manifestations of the LIR are predictive of long-term clinical benefits....
Quality and reproducibility of spirometry in COPD patients in a randomized trial (UPLIFT®).
Janssens W, Liu Y, Liu D, Kesten S, Tashkin DP, Celli BR, Decramer M. Janssens W, et al. Among authors: kesten s. Respir Med. 2013 Sep;107(9):1409-16. doi: 10.1016/j.rmed.2013.04.015. Epub 2013 May 25. Respir Med. 2013. PMID: 23714653 Free article. Clinical Trial.
BACKGROUND: This study explores spirometry quality and reproducibility in the Understanding Potential Long-term Impacts on Function with Tiotropium (UPLIFT()) trial. METHODS: Four-year, randomized, double-blind, placebo-controlled, multicenter trial in 5993 patients with c …
BACKGROUND: This study explores spirometry quality and reproducibility in the Understanding Potential Long-term Impacts on Function w …
Exacerbation frequency and course of COPD.
Halpin DM, Decramer M, Celli B, Kesten S, Liu D, Tashkin DP. Halpin DM, et al. Among authors: kesten s. Int J Chron Obstruct Pulmon Dis. 2012;7:653-61. doi: 10.2147/COPD.S34186. Epub 2012 Sep 21. Int J Chron Obstruct Pulmon Dis. 2012. PMID: 23055714 Free PMC article.
We sought to evaluate the association between exacerbation frequency and spirometric and health status changes over time using data from a large, long-term trial. METHODS: This retrospective analysis of data from the 4-year UPLIFT (Understanding Potential Long-term …
We sought to evaluate the association between exacerbation frequency and spirometric and health status changes over time using data from a l …
Longitudinal inspiratory capacity changes in chronic obstructive pulmonary disease.
Celli BR, Decramer M, Lystig T, Kesten S, Tashkin DP. Celli BR, et al. Among authors: kesten s. Respir Res. 2012 Aug 6;13(1):66. doi: 10.1186/1465-9921-13-66. Respir Res. 2012. PMID: 22866681 Free PMC article. Clinical Trial.
BACKGROUND: The changes in inspiratory capacity (IC) over time in chronic obstructive pulmonary disease (COPD) patients are unknown. The Understanding Potential Long-term Impacts on Function with Tiotropium (UPLIFT) trial included IC measurements. ...Tiotropium treatment d …
BACKGROUND: The changes in inspiratory capacity (IC) over time in chronic obstructive pulmonary disease (COPD) patients are unknown. The Und …
Cause-specific mortality adjudication in the UPLIFT® COPD trial: findings and recommendations.
McGarvey LP, Magder S, Burkhart D, Kesten S, Liu D, Manuel RC, Niewoehner DE. McGarvey LP, et al. Among authors: kesten s. Respir Med. 2012 Apr;106(4):515-21. doi: 10.1016/j.rmed.2011.10.009. Epub 2011 Nov 18. Respir Med. 2012. PMID: 22100536 Free article. Clinical Trial.
Mortality is an important endpoint in chronic obstructive pulmonary disease (COPD) trials, although accurately determining cause of death is difficult. In the Understanding the Potential Long-term Impacts on Function with Tiotropium (UPLIFT) trial, a mortality adjudication …
Mortality is an important endpoint in chronic obstructive pulmonary disease (COPD) trials, although accurately determining cause of death is …
Risk of nonlower respiratory serious adverse events following COPD exacerbations in the 4-year UPLIFT® trial.
Halpin DM, Decramer M, Celli B, Kesten S, Leimer I, Tashkin DP. Halpin DM, et al. Among authors: kesten s. Lung. 2011 Aug;189(4):261-8. doi: 10.1007/s00408-011-9301-8. Epub 2011 Jun 16. Lung. 2011. PMID: 21678045 Free PMC article.
INTRODUCTION: Chronic obstructive pulmonary disease (COPD) exacerbations are associated with systemic consequences. Data from a 4-year trial (Understanding Potential Long-term Impacts on Function with Tiotropium [UPLIFT()], n = 5,992) were used to determine risk for nonlow …
INTRODUCTION: Chronic obstructive pulmonary disease (COPD) exacerbations are associated with systemic consequences. Data from a 4-year trial …
Acute bronchodilator responsiveness and health outcomes in COPD patients in the UPLIFT trial.
Hanania NA, Sharafkhaneh A, Celli B, Decramer M, Lystig T, Kesten S, Tashkin D. Hanania NA, et al. Among authors: kesten s. Respir Res. 2011 Jan 11;12(1):6. doi: 10.1186/1465-9921-12-6. Respir Res. 2011. PMID: 21219660 Free PMC article. Clinical Trial.
BACKGROUND: Debate continues as to whether acute bronchodilator responsiveness (BDR) predicts long-term outcomes in COPD. Furthermore, there is no consensus on a threshold for BDR. METHODS: At baseline and during the 4-year Understanding Potential Long-term Improvem …
BACKGROUND: Debate continues as to whether acute bronchodilator responsiveness (BDR) predicts long-term outcomes in COPD. Furthermore …
COPD in young patients: a pre-specified analysis of the four-year trial of tiotropium (UPLIFT).
Morice AH, Celli B, Kesten S, Lystig T, Tashkin D, Decramer M. Morice AH, et al. Among authors: kesten s. Respir Med. 2010 Nov;104(11):1659-67. doi: 10.1016/j.rmed.2010.07.016. Epub 2010 Aug 17. Respir Med. 2010. PMID: 20724131 Free article. Clinical Trial.
We report a pre-specified post-hoc analysis of 356 patients with COPD 50 years old from the four year randomised, double blind placebo controlled Understanding Potential Long Term Impact on Function with Tiotropium (UPLIFT) trial. Inclusion criteria included a post-broncho …
We report a pre-specified post-hoc analysis of 356 patients with COPD 50 years old from the four year randomised, double blind placebo contr …
Effect of tiotropium in men and women with COPD: results of the 4-year UPLIFT trial.
Tashkin D, Celli B, Kesten S, Lystig T, Decramer M. Tashkin D, et al. Among authors: kesten s. Respir Med. 2010 Oct;104(10):1495-504. doi: 10.1016/j.rmed.2010.03.033. Epub 2010 Apr 24. Respir Med. 2010. PMID: 20418083 Free article. Clinical Trial.
We have examined the influence of gender in chronic obstructive pulmonary disease (COPD) on long-term responses to tiotropium. METHODS: Subgroup analysis of data from the Understanding the Potential Long-term Impact of Tiotropium (UPLIFT) trial (4-year, randomized, …
We have examined the influence of gender in chronic obstructive pulmonary disease (COPD) on long-term responses to tiotropium. METHOD …
Tiotropium as a first maintenance drug in COPD: secondary analysis of the UPLIFT trial.
Troosters T, Celli B, Lystig T, Kesten S, Mehra S, Tashkin DP, Decramer M; Uplift Investigators. Troosters T, et al. Among authors: kesten s. Eur Respir J. 2010 Jul;36(1):65-73. doi: 10.1183/09031936.00127809. Epub 2010 Feb 25. Eur Respir J. 2010. PMID: 20185426 Free article. Clinical Trial.
The aim of the present study was investigate the long-term effect of tiotropium as first maintenance respiratory medication in chronic obstructive pulmonary disease (COPD). A 4-yr, randomised, multicentre, double-blind, parallel-group, placebo-controlled trial (Understandi …
The aim of the present study was investigate the long-term effect of tiotropium as first maintenance respiratory medication in chroni …
31 results