Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My NCBI Filters

Text availability

Article attribute

Article type

Publication date

Search Results

72 results

Filters applied: . Clear all
Page 1
Effect of a single small volume fluid bolus with balanced or un-balanced fluids on chloride and acid-base status: a prospective randomized pilot study (the FLURES-trial).
Raes M, Kellum JA, Colman R, Wallaert S, Crivits M, Viaene F, Hemeryck M, Benoit D, Poelaert J, Hoste E. Raes M, et al. Among authors: kellum ja. J Nephrol. 2024 Mar 28. doi: 10.1007/s40620-024-01912-z. Online ahead of print. J Nephrol. 2024. PMID: 38546940
OBJECTIVE: To compare the short-term effects on acid base, electrolyte status and urine output of a single fluid bolus of saline to that of the balanced solution Plasmalyte() in critically ill patients. ...MAIN RESULTS: Patients who received a 1 L saline fluid bolus had a …
OBJECTIVE: To compare the short-term effects on acid base, electrolyte status and urine output of a single fluid bolus of saline to t …
Endotoxic Septic Shock: Diagnosis and Treatment.
Foster DM, Kellum JA. Foster DM, et al. Among authors: kellum ja. Int J Mol Sci. 2023 Nov 10;24(22):16185. doi: 10.3390/ijms242216185. Int J Mol Sci. 2023. PMID: 38003374 Free PMC article. Review.
Endotoxin, also referred to as lipopolysaccharide (LPS), is a potent stimulator of the inflammatory cascade which may progress to sepsis and septic shock. The term endotoxic septic shock has been used for patients who have a clinical phenotype that is characterized by high …
Endotoxin, also referred to as lipopolysaccharide (LPS), is a potent stimulator of the inflammatory cascade which may progress to sepsis and …
The role of endotoxin in septic shock.
Kellum JA, Ronco C. Kellum JA, et al. Crit Care. 2023 Oct 19;27(1):400. doi: 10.1186/s13054-023-04690-5. Crit Care. 2023. PMID: 37858258 Free PMC article. Review.
Annually, approximately 5-7 million patients worldwide develop sepsis with very high endotoxin activity in the blood and more than half die. The term endotoxic septic shock has been used for these patients but it is important to emphasize that endotoxin may be a factor in …
Annually, approximately 5-7 million patients worldwide develop sepsis with very high endotoxin activity in the blood and more than half die. …
Adsorption of Endotoxin and Mitigation of Sepsis.
Kellum JA, Shoji H, Foster DM, Walker PM. Kellum JA, et al. Contrib Nephrol. 2023;200:133-141. doi: 10.1159/000527708. Epub 2023 Jun 1. Contrib Nephrol. 2023. PMID: 37263237 Review.
In the fields of sepsis and systemic inflammation, endotoxin might be the most studied molecule since the term was coined by Richard Pfeiffer in 1892. Paradoxically measuring endotoxin in humans and finding an effective treatment for endotoxemia have remained challenging. …
In the fields of sepsis and systemic inflammation, endotoxin might be the most studied molecule since the term was coined by Richard …
Kidney Cell Cycle Arrest and Cardiac Biomarkers and Acute Kidney Injury Following Angiography: The Prevention of Serious Adverse Events Following Angiography (PRESERVE) Study.
Murugan R, Boudreaux-Kelly MY, Kellum JA, Palevsky PM, Weisbord S; Biomarker Effectiveness Analysis in Contrast Nephropathy (BEACON) Study Investigators. Murugan R, et al. Among authors: kellum ja. Kidney Med. 2022 Dec 21;5(3):100592. doi: 10.1016/j.xkme.2022.100592. eCollection 2023 Mar. Kidney Med. 2022. PMID: 36874509 Free PMC article.
Significant elevation in preangiography cardiac biomarkers may reflect patients with more significant cardiovascular disease that may predispose to poor long-term outcomes independent of CA-AKI status....
Significant elevation in preangiography cardiac biomarkers may reflect patients with more significant cardiovascular disease that may predis …
Recovery after AKI: Effects on outcomes over 15 years.
Peerapornratana S, Fiorentino M, Priyanka P, Murugan R, Kellum JA. Peerapornratana S, et al. Among authors: kellum ja. J Crit Care. 2023 Aug;76:154280. doi: 10.1016/j.jcrc.2023.154280. Epub 2023 Feb 26. J Crit Care. 2023. PMID: 36848723
CONCLUSIONS: Recovery of AKI in critically ill patients at hospital discharge had an effect on long-term mortality for up to 15 years. These results have implications for acute care, follow-up and choice of endpoints for clinical trials....
CONCLUSIONS: Recovery of AKI in critically ill patients at hospital discharge had an effect on long-term mortality for up to 15 years …
VASOPRESSOR-RESISTANT HYPOTENSION, COMBINATION VASOPRESSOR THERAPY, AND SHOCK PHENOTYPES IN CRITICALLY ILL ADULTS WITH VASODILATORY SHOCK.
Priyanka P, Chang CH, Chawla LS, Kellum JA, Clermont G, Murugan R. Priyanka P, et al. Among authors: kellum ja. Shock. 2022 Oct 1;58(4):260-268. doi: 10.1097/SHK.0000000000001980. Epub 2022 Aug 18. Shock. 2022. PMID: 36018286 Free PMC article.
Conclusions: Among critically ill patients with vasodilatory shock, VRH compared with VSH is associated with increased resource utilization and long-term risk of death. However, combination vasopressor therapy was not associated with lower risk of death. ...
Conclusions: Among critically ill patients with vasodilatory shock, VRH compared with VSH is associated with increased resource utilization …
Effects of preoperative high-oral protein loading on short- and long-term renal outcomes following cardiac surgery: a cohort study.
Husain-Syed F, Emlet DR, Wilhelm J, Danesi TH, Ferrari F, Bezerra P, Lopez-Giacoman S, Villa G, Tello K, Birk HW, Seeger W, Giavarina D, Salvador L, Fuhrman DY, Kellum JA, Ronco C; IRRIV-AKI Study Group. Husain-Syed F, et al. Among authors: kellum ja. J Transl Med. 2022 May 10;20(1):204. doi: 10.1186/s12967-022-03410-x. J Transl Med. 2022. PMID: 35538495 Free PMC article.
The epidemiology and long-term outcomes of acute kidney disease in a resource-limited setting.
Lertussavavivat T, Kulvichit W, Peerapornratana S, Lumlertgul N, Bhumitrakul J, Tungsanga K, Eiam-Ong S, Avihingsanon Y, Kellum JA, Srisawat N. Lertussavavivat T, et al. Among authors: kellum ja. J Nephrol. 2022 Dec;35(9):2283-2292. doi: 10.1007/s40620-022-01328-7. Epub 2022 Apr 21. J Nephrol. 2022. PMID: 35445946
CONCLUSION: In a resource-limited setting, AKD is associated with short- and long-term mortality and CKD progression, especially in individuals with pre-existing CKD....
CONCLUSION: In a resource-limited setting, AKD is associated with short- and long-term mortality and CKD progression, especially in i …
Acute kidney injury.
Kellum JA, Romagnani P, Ashuntantang G, Ronco C, Zarbock A, Anders HJ. Kellum JA, et al. Nat Rev Dis Primers. 2021 Jul 15;7(1):52. doi: 10.1038/s41572-021-00284-z. Nat Rev Dis Primers. 2021. PMID: 34267223 Review.
As AKI can be lethal, kidney replacement therapy is frequently required. AKI has a poor prognosis in critically ill patients. Long-term consequences of AKI and AKD include CKD and cardiovascular morbidity. ...
As AKI can be lethal, kidney replacement therapy is frequently required. AKI has a poor prognosis in critically ill patients. Long-term …
72 results