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Predictors of non-recovery from fatigue and cognitive deficits after COVID-19: a prospective, longitudinal, population-based study.
Hartung TJ, Bahmer T, Chaplinskaya-Sobol I, Deckert J, Endres M, Franzpötter K, Geritz J, Haeusler KG, Hein G, Heuschmann PU, Hopff SM, Horn A, Keil T, Krawczak M, Krist L, Lieb W, Maetzler C, Montellano FA, Morbach C, Neumann C, Nürnberger C, Russ AK, Schmidbauer L, Schmidt S, Schreiber S, Steigerwald F, Störk S, Zoller T, Maetzler W, Finke C; NAPKON Study Group. Hartung TJ, et al. Among authors: keil t. EClinicalMedicine. 2024 Feb 3;69:102456. doi: 10.1016/j.eclinm.2024.102456. eCollection 2024 Mar. EClinicalMedicine. 2024. PMID: 38333368 Free PMC article.
BACKGROUND: Despite the high prevalence and major disability associated with fatigue and cognitive deficits after SARS-CoV-2 infection, little is known about long-term trajectories of these sequelae. We aimed to assess long-term trajectories of these conditions and …
BACKGROUND: Despite the high prevalence and major disability associated with fatigue and cognitive deficits after SARS-CoV-2 infection, litt …
Fear extinction rescuing effects of dopamine and L-DOPA in the ventromedial prefrontal cortex.
Sartori SB, Keil TMV, Kummer KK, Murphy CP, Gunduz-Cinar O, Kress M, Ebner K, Holmes A, Singewald N. Sartori SB, et al. Among authors: keil tmv. Transl Psychiatry. 2024 Jan 8;14(1):11. doi: 10.1038/s41398-023-02708-8. Transl Psychiatry. 2024. PMID: 38191458 Free PMC article.
Conversely, direct microinfusion of DA into IL produced long-term fear extinction (an effect that was insensitive to -/ss-adrenoreceptor antagonism). ...
Conversely, direct microinfusion of DA into IL produced long-term fear extinction (an effect that was insensitive to -/ss-adrenorecep …
Increased circulating fibronectin, depletion of natural IgM and heightened EBV, HSV-1 reactivation in ME/CFS and long COVID.
Liu Z, Hollmann C, Kalanidhi S, Grothey A, Keating S, Mena-Palomo I, Lamer S, Schlosser A, Kaiping A, Scheller C, Sotzny F, Horn A, Nürnberger C, Cejka V, Afshar B, Bahmer T, Schreiber S, Vehreschild JJ, Miljukov O, Schäfer C, Kretzler L, Keil T, Reese JP, Eichner FA, Schmidbauer L, Heuschmann PU, Störk S, Morbach C, Riemekasten G, Beyersdorf N, Scheibenbogen C, Naviaux RK, Williams M, Ariza ME, Prusty BK. Liu Z, et al. Among authors: keil t. medRxiv [Preprint]. 2023 Jun 29:2023.06.23.23291827. doi: 10.1101/2023.06.23.23291827. medRxiv. 2023. PMID: 37425897 Free PMC article. Preprint.
Myalgic Encephalomyelitis/ Chronic Fatigue syndrome (ME/CFS) is a complex, debilitating, long-term illness without a diagnostic biomarker. ME/CFS patients share overlapping symptoms with long COVID patients, an observation which has strengthened the infectious origin hypot …
Myalgic Encephalomyelitis/ Chronic Fatigue syndrome (ME/CFS) is a complex, debilitating, long-term illness without a diagnostic bioma …
Comparing the occurrence of chronic physical disorders in self-employed individuals with that of employees: A systematic review.
Willeke K, Janson P, Zink K, Tischer C, Heuschmann PU, Zapf A, Wildner M, Stupp C, Keil T. Willeke K, et al. Among authors: keil t. Work. 2023;75(4):1179-1198. doi: 10.3233/WOR-220145. Work. 2023. PMID: 36710710 Free PMC article. Review.
In cross-sectional studies, prevalence estimates for musculoskeletal, respiratory and malignant diseases were higher among self-employed individuals than among employees. CONCLUSION: The long-term cardiovascular disease risk and mortality of self-employed individuals seeme …
In cross-sectional studies, prevalence estimates for musculoskeletal, respiratory and malignant diseases were higher among self-employed ind …
Systematic review with meta-analysis: Stress-management interventions for patients with irritable bowel syndrome.
Horn A, Stangl S, Parisi S, Bauer N, Roll J, Löffler C, Gágyor I, Haas K, Heuschmann PU, Langhorst J, Keil T. Horn A, et al. Among authors: keil t. Stress Health. 2023 Oct;39(4):694-707. doi: 10.1002/smi.3226. Epub 2023 Jan 31. Stress Health. 2023. PMID: 36649166 Review.
Our meta-analysis showed no effect of stress-management on IBS severity 1-2 months after the intervention (Hedges' g = -0.23, 95%-CI = -0.84 to -0.38, I(2) = 86.1%), and after 3-12 months (Hedges' g = -0.77, 95%-CI = -1.77 to -0.23, I(2) = 93.3%). One trial found a short-term …
Our meta-analysis showed no effect of stress-management on IBS severity 1-2 months after the intervention (Hedges' g = -0.23, 95%-CI = -0.84 …
The German National Pandemic Cohort Network (NAPKON): rationale, study design and baseline characteristics.
Schons M, Pilgram L, Reese JP, Stecher M, Anton G, Appel KS, Bahmer T, Bartschke A, Bellinghausen C, Bernemann I, Brechtel M, Brinkmann F, Brünn C, Dhillon C, Fiessler C, Geisler R, Hamelmann E, Hansch S, Hanses F, Hanß S, Herold S, Heyder R, Hofmann AL, Hopff SM, Horn A, Jakob C, Jiru-Hillmann S, Keil T, Khodamoradi Y, Kohls M, Kraus M, Krefting D, Kunze S, Kurth F, Lieb W, Lippert LJ, Lorbeer R, Lorenz-Depiereux B, Maetzler C, Miljukov O, Nauck M, Pape D, Püntmann V, Reinke L, Römmele C, Rudolph S, Sass J, Schäfer C, Schaller J, Schattschneider M, Scheer C, Scherer M, Schmidt S, Schmidt J, Seibel K, Stahl D, Steinbeis F, Störk S, Tauchert M, Tebbe JJ, Thibeault C, Toepfner N, Ungethüm K, Vadasz I, Valentin H, Wiedmann S, Zoller T, Nagel E, Krawczak M, von Kalle C, Illig T, Schreiber S, Witzenrath M, Heuschmann P, Vehreschild JJ; NAPKON Research Group. Schons M, et al. Among authors: keil t. Eur J Epidemiol. 2022 Aug;37(8):849-870. doi: 10.1007/s10654-022-00896-z. Epub 2022 Jul 29. Eur J Epidemiol. 2022. PMID: 35904671 Free PMC article. Review.
Severity, predictors and clinical correlates of Post-COVID syndrome (PCS) in Germany: A prospective, multi-centre, population-based cohort study.
Bahmer T, Borzikowsky C, Lieb W, Horn A, Krist L, Fricke J, Scheibenbogen C, Rabe KF, Maetzler W, Maetzler C, Laudien M, Frank D, Ballhausen S, Hermes A, Miljukov O, Haeusler KG, Mokhtari NEE, Witzenrath M, Vehreschild JJ, Krefting D, Pape D, Montellano FA, Kohls M, Morbach C, Störk S, Reese JP, Keil T, Heuschmann P, Krawczak M, Schreiber S; NAPKON study group. Bahmer T, et al. Among authors: keil t. EClinicalMedicine. 2022 Jul 18;51:101549. doi: 10.1016/j.eclinm.2022.101549. eCollection 2022 Sep. EClinicalMedicine. 2022. PMID: 35875815 Free PMC article.
In sub-cohort Kiel-I, a PCS (severity) score was developed based upon 12 long-term symptom complexes. Two validation sub-cohorts (Wurzburg/Berlin, Kiel-II) were used for PCS score replication and identification of clinically meaningful predictors. ...
In sub-cohort Kiel-I, a PCS (severity) score was developed based upon 12 long-term symptom complexes. Two validation sub-cohorts (Wur …
Interplay between natural environment, human microbiota and immune system: A scoping review of interventions and future perspectives towards allergy prevention.
Tischer C, Kirjavainen P, Matterne U, Tempes J, Willeke K, Keil T, Apfelbacher C, Täubel M. Tischer C, et al. Among authors: keil t. Sci Total Environ. 2022 May 15;821:153422. doi: 10.1016/j.scitotenv.2022.153422. Epub 2022 Jan 25. Sci Total Environ. 2022. PMID: 35090907 Free article. Review.
The interventions reported were mainly of pilot character and various, ranging from nature-related educational programs, biodiversity interventions in day-cares to short-term contact with soil- and sand-preparations. Most of the studied interventions appeared to increase h …
The interventions reported were mainly of pilot character and various, ranging from nature-related educational programs, biodiversity interv …
Strategies to Enhance Retention in a Cohort Study Among Adults of Turkish Descent Living in Berlin.
Dornquast C, Reinhold T, Solak S, Durak M, Becher H, Riens B, Icke K, Danquah I, Willich SN, Keil T, Krist L. Dornquast C, et al. Among authors: keil t. J Immigr Minor Health. 2022 Oct;24(5):1309-1317. doi: 10.1007/s10903-021-01309-1. Epub 2021 Nov 19. J Immigr Minor Health. 2022. PMID: 34797452 Free PMC article.
Retention is important for statistical power and external validity in long-term cohort studies. The aims of our study were to evaluate different retention strategies within a cohort study of adults of Turkish descent in Berlin, Germany, and to compare participants and non- …
Retention is important for statistical power and external validity in long-term cohort studies. The aims of our study were to evaluat …
Long-term health sequelae and quality of life at least 6 months after infection with SARS-CoV-2: design and rationale of the COVIDOM-study as part of the NAPKON population-based cohort platform (POP).
Horn A, Krist L, Lieb W, Montellano FA, Kohls M, Haas K, Gelbrich G, Bolay-Gehrig SJ, Morbach C, Reese JP, Störk S, Fricke J, Zoller T, Schmidt S, Triller P, Kretzler L, Rönnefarth M, Von Kalle C, Willich SN, Kurth F, Steinbeis F, Witzenrath M, Bahmer T, Hermes A, Krawczak M, Reinke L, Maetzler C, Franzenburg J, Enderle J, Flinspach A, Vehreschild J, Schons M, Illig T, Anton G, Ungethüm K, Finkenberg BC, Gehrig MT, Savaskan N, Heuschmann PU, Keil T, Schreiber S. Horn A, et al. Among authors: keil t. Infection. 2021 Dec;49(6):1277-1287. doi: 10.1007/s15010-021-01707-5. Epub 2021 Oct 12. Infection. 2021. PMID: 34642875 Free PMC article.
PURPOSE: Over the course of COVID-19 pandemic, evidence has accumulated that SARS-CoV-2 infections may affect multiple organs and have serious clinical sequelae, but on-site clinical examinations with non-hospitalized samples are rare. We, therefore, aimed to systematically asses …
PURPOSE: Over the course of COVID-19 pandemic, evidence has accumulated that SARS-CoV-2 infections may affect multiple organs and have serio …
44 results