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Brain-computer interface relieves chronic chemotherapy-induced peripheral neuropathy: A randomized, double-blind, placebo-controlled trial.
Prinsloo S, Kaptchuk TJ, De Ridder D, Lyle R, Bruera E, Novy D, Barcenas CH, Cohen LG. Prinsloo S, et al. Among authors: kaptchuk tj. Cancer. 2024 Jan;130(2):300-311. doi: 10.1002/cncr.35027. Epub 2023 Sep 21. Cancer. 2024. PMID: 37733286 Clinical Trial.
CONCLUSIONS: BCI is a promising treatment for CIPN and may have a longer lasting effect than placebo (nonspecific BCI), which is an important consideration for long-term symptom relief. Although scientifically interesting, the ability to separate real from placebo treatmen …
CONCLUSIONS: BCI is a promising treatment for CIPN and may have a longer lasting effect than placebo (nonspecific BCI), which is an importan …
Quantifying and controlling the impact of regression to the mean on randomized controlled trials in epilepsy.
Goldenholz DM, Goldenholz EB, Kaptchuk TJ. Goldenholz DM, et al. Among authors: kaptchuk tj. Epilepsia. 2023 Oct;64(10):2635-2643. doi: 10.1111/epi.17730. Epub 2023 Aug 8. Epilepsia. 2023. PMID: 37505116
Here, RTM represents an initial observed seizure rate higher than the long-term average, which gradually settles closer to the average, resulting in apparent response to treatment. ...
Here, RTM represents an initial observed seizure rate higher than the long-term average, which gradually settles closer to the averag …
Open-label placebo for chronic low back pain: a 5-year follow-up.
Carvalho C, Pais M, Cunha L, Rebouta P, Kaptchuk TJ, Kirsch I. Carvalho C, et al. Among authors: kaptchuk tj. Pain. 2021 May 1;162(5):1521-1527. doi: 10.1097/j.pain.0000000000002162. Pain. 2021. PMID: 33259459 Clinical Trial.
Long-term follow-up of patients treated with open-label placebo (OLP) are nonexistent. ...Although the reduction in pain and medication is comparable with the improvements that occurred in the original study, a major limitation of this long-term follow-up is the abs …
Long-term follow-up of patients treated with open-label placebo (OLP) are nonexistent. ...Although the reduction in pain and medicati …
Network analysis of the genomic basis of the placebo effect.
Wang RS, Hall KT, Giulianini F, Passow D, Kaptchuk TJ, Loscalzo J. Wang RS, et al. Among authors: kaptchuk tj. JCI Insight. 2017 Jun 2;2(11):e93911. doi: 10.1172/jci.insight.93911. eCollection 2017 Jun 2. JCI Insight. 2017. PMID: 28570268 Free PMC article.
Recent observations suggest that placebo effects may be modified by genetics. This observation has given rise to the term "placebome," which refers to a group of genome-related mediators that affect an individual's response to placebo treatments. ...
Recent observations suggest that placebo effects may be modified by genetics. This observation has given rise to the term "placebome, …
Rewiring the primary somatosensory cortex in carpal tunnel syndrome with acupuncture.
Maeda Y, Kim H, Kettner N, Kim J, Cina S, Malatesta C, Gerber J, McManus C, Ong-Sutherland R, Mezzacappa P, Libby A, Mawla I, Morse LR, Kaptchuk TJ, Audette J, Napadow V. Maeda Y, et al. Among authors: kaptchuk tj. Brain. 2017 Apr 1;140(4):914-927. doi: 10.1093/brain/awx015. Brain. 2017. PMID: 28334999 Free PMC article. Clinical Trial.
Our study further suggests that improvements in primary somatosensory cortex somatotopy can predict long-term clinical outcomes for carpal tunnel syndrome....
Our study further suggests that improvements in primary somatosensory cortex somatotopy can predict long-term clinical outcomes for c …
Structural integration as an adjunct to outpatient rehabilitation for chronic nonspecific low back pain: a randomized pilot clinical trial.
Jacobson EE, Meleger AL, Bonato P, Wayne PM, Langevin HM, Kaptchuk TJ, Davis RB. Jacobson EE, et al. Among authors: kaptchuk tj. Evid Based Complement Alternat Med. 2015;2015:813418. doi: 10.1155/2015/813418. Epub 2015 Apr 7. Evid Based Complement Alternat Med. 2015. PMID: 25945112 Free PMC article.
SI as an adjunct to OR for CNSLBP is not likely to provide additional reductions in pain but is likely to augment short term improvements in disability with a low additional burden of AE. ...
SI as an adjunct to OR for CNSLBP is not likely to provide additional reductions in pain but is likely to augment short term improvem …
Placebos in 19th century medicine: a quantitative analysis of the BMJ.
Raicek JE, Stone BH, Kaptchuk TJ. Raicek JE, et al. Among authors: kaptchuk tj. BMJ. 2012 Dec 18;345:e8326. doi: 10.1136/bmj.e8326. BMJ. 2012. PMID: 23249668 Free PMC article.
OBJECTIVE: To provide the first quantitative data on the use of the term "placebo" in the 19th century. DESIGN: Computer search of BMJ's archival database from January 1840 (the first issue) through December 1899 for uses of the words "placebo(s)." Grounded theory was used …
OBJECTIVE: To provide the first quantitative data on the use of the term "placebo" in the 19th century. DESIGN: Computer search of BM …
Challenges inherent to t'ai chi research: part II-defining the intervention and optimal study design.
Wayne PM, Kaptchuk TJ. Wayne PM, et al. Among authors: kaptchuk tj. J Altern Complement Med. 2008 Mar;14(2):191-7. doi: 10.1089/acm.2007.7170b. J Altern Complement Med. 2008. PMID: 18446928 Review.
These challenges include t'ai chi's pluralism, the concept of t'ai chi dosage, and long- versus short-term evaluations of t'ai chi's efficacy and safety. To address these challenges, and with a goal to provide complete and unbiased evidence, we propose a pluralistic method …
These challenges include t'ai chi's pluralism, the concept of t'ai chi dosage, and long- versus short-term evaluations of t'ai chi's …
Acupuncture de qi, from qualitative history to quantitative measurement.
Kong J, Gollub R, Huang T, Polich G, Napadow V, Hui K, Vangel M, Rosen B, Kaptchuk TJ. Kong J, et al. Among authors: kaptchuk tj. J Altern Complement Med. 2007 Dec;13(10):1059-70. doi: 10.1089/acm.2007.0524. J Altern Complement Med. 2007. PMID: 18166116 Review.
De qi is an important traditional acupuncture term used to describe the connection between acupuncture needles and the energy pathways of the body. ...
De qi is an important traditional acupuncture term used to describe the connection between acupuncture needles and the energy pathway …
Systematic review of the effects of ginseng on cardiovascular risk factors.
Buettner C, Yeh GY, Phillips RS, Mittleman MA, Kaptchuk TJ. Buettner C, et al. Among authors: kaptchuk tj. Ann Pharmacother. 2006 Jan;40(1):83-95. doi: 10.1345/aph.1G216. Epub 2005 Dec 6. Ann Pharmacother. 2006. PMID: 16332943 Review.
DATA SOURCES: We searched MEDLINE, AMED, BIOSIS, CAB, EMBASE, and the Cochrane Controlled Trials databases through July 2005 and performed hand searches of bibliographies. STUDY SELECTION AND DATA EXTRACTION: Short- or long-term, randomized, controlled trials and nonrandom …
DATA SOURCES: We searched MEDLINE, AMED, BIOSIS, CAB, EMBASE, and the Cochrane Controlled Trials databases through July 2005 and performed h …
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