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Page 1
A Simple Tube Escape Assay to Test Learning and Memory in Zebrafish with Minimized Habituation.
Wellalage Don D, Kim TY, Hong BN, Lee JS, Kang TH, Gerlai R, Kim CH. Wellalage Don D, et al. Among authors: kang th. Zebrafish. 2024 May 15. doi: 10.1089/zeb.2023.0045. Online ahead of print. Zebrafish. 2024. PMID: 38748396
We demonstrate that in this task, zebrafish could acquire both short-term (1 h) and long-term memory (4 days). We also studied learning and memory of a gene knockout (KO) zebrafish that showed social impairments related to autism. ...
We demonstrate that in this task, zebrafish could acquire both short-term (1 h) and long-term memory (4 days). We also studied …
Panax ginseng (Korea Red Ginseng) repairs diabetic sensorineural damage through promotion of the nerve growth factor pathway in diabetic zebrafish.
Nam YH, Moon HW, Lee YR, Kim EY, Rodriguez I, Jeong SY, Castañeda R, Park JH, Choung SY, Hong BN, Kang TH. Nam YH, et al. Among authors: kang th. J Ginseng Res. 2019 Apr;43(2):272-281. doi: 10.1016/j.jgr.2018.02.006. Epub 2018 Feb 16. J Ginseng Res. 2019. PMID: 30976165 Free PMC article.
BACKGROUND: Diabetic sensorineural damage is a complication of the sensory neural system, resulting from long-term hyperglycemia. Red ginseng (RG) has shown efficacy for treatment of various diseases, including diabetes mellitus; however, there is little research about its …
BACKGROUND: Diabetic sensorineural damage is a complication of the sensory neural system, resulting from long-term hyperglycemia. Red …
A novel function of API5 (apoptosis inhibitor 5), TLR4-dependent activation of antigen presenting cells.
Kim YS, Park HJ, Park JH, Hong EJ, Jang GY, Jung ID, Han HD, Lee SH, Vo MC, Lee JJ, Yang A, Farmer E, Wu TC, Kang TH, Park YM. Kim YS, et al. Among authors: kang th. Oncoimmunology. 2018 Aug 15;7(10):e1472187. doi: 10.1080/2162402X.2018.1472187. eCollection 2018. Oncoimmunology. 2018. PMID: 30288341 Free PMC article.
We also demonstrated that vaccination with API5-treated DCs pulsed with OVA, E7, or AH1-A5 peptides led to the generation of OVA, E7, or AH1-A5-specific CD8 + T cells and memory T cells, which is associated with long term tumor protection and antitumor effects in mice, aga …
We also demonstrated that vaccination with API5-treated DCs pulsed with OVA, E7, or AH1-A5 peptides led to the generation of OVA, E7, or AH1 …
Protein adsorption of dialdehyde cellulose-crosslinked chitosan with high amino group contents.
Kim UJ, Lee YR, Kang TH, Choi JW, Kimura S, Wada M. Kim UJ, et al. Among authors: kang th. Carbohydr Polym. 2017 May 1;163:34-42. doi: 10.1016/j.carbpol.2017.01.052. Epub 2017 Jan 18. Carbohydr Polym. 2017. PMID: 28267516
DAC-crosslinked chitosan showed higher stability in the pH 2-9 range and no cytotoxicity was identified over the course of a 21-day long-term stability test. Also, DAC-crosslinked chitosan showed remarkably high bovine serum albumin (BSA) adsorption capacity at pH 5.5 as a …
DAC-crosslinked chitosan showed higher stability in the pH 2-9 range and no cytotoxicity was identified over the course of a 21-day long- …
Pancreatic adenocarcinoma upregulated factor serves as adjuvant by activating dendritic cells through stimulation of TLR4.
Kang TH, Kim YS, Kim S, Yang B, Lee JJ, Lee HJ, Lee J, Jung ID, Han HD, Lee SH, Koh SS, Wu TC, Park YM. Kang TH, et al. Oncotarget. 2015 Sep 29;6(29):27751-62. doi: 10.18632/oncotarget.4859. Oncotarget. 2015. PMID: 26336989 Free PMC article.
Furthermore, vaccination with PAUF treated DCs pulsed with E7 or OVA peptides leads to generation of E7 or OVA-specific CD8+ T cells and memory T cells, which correlate with long term tumor protection and antitumor effects against TC-1 and EG.7 tumors in mice. ...
Furthermore, vaccination with PAUF treated DCs pulsed with E7 or OVA peptides leads to generation of E7 or OVA-specific CD8+ T cells and mem …
Short-term outcomes of immediate breast reconstruction using an implant or tissue expander after mastectomy in breast cancer patients.
Kim SW, Lee HK, Kang SM, Kang TH, Yoon CS, Ko SS, Hur MH, Kang SS, Seul CH, Gu JS. Kim SW, et al. Among authors: kang th. Breast Cancer. 2016 Mar;23(2):279-85. doi: 10.1007/s12282-014-0570-y. Epub 2014 Oct 22. Breast Cancer. 2016. PMID: 25336184
In addition, the reconstruction resulted in a relatively high rate of patient satisfaction. Further long-term studies are warranted to confirm these findings....
In addition, the reconstruction resulted in a relatively high rate of patient satisfaction. Further long-term studies are warranted t …
A potential protein adjuvant derived from Mycobacterium tuberculosis Rv0652 enhances dendritic cells-based tumor immunotherapy.
Lee SJ, Shin SJ, Lee MH, Lee MG, Kang TH, Park WS, Soh BY, Park JH, Shin YK, Kim HW, Yun CH, Jung ID, Park YM. Lee SJ, et al. Among authors: kang th. PLoS One. 2014 Aug 7;9(8):e104351. doi: 10.1371/journal.pone.0104351. eCollection 2014. PLoS One. 2014. PMID: 25102137 Free PMC article.
Immunization of mice with Rv0652-stimulated ovalbumin (OVA)-pulsed DCs resulted in induction of a potent OVA-specific CD8+ T cell response, slowed tumor growth, and promoted long-term survival in a murine OVA-expressing E.G7 thymoma model. These findings suggest that Rv065 …
Immunization of mice with Rv0652-stimulated ovalbumin (OVA)-pulsed DCs resulted in induction of a potent OVA-specific CD8+ T cell response, …
Chemotherapy acts as an adjuvant to convert the tumor microenvironment into a highly permissive state for vaccination-induced antitumor immunity.
Kang TH, Mao CP, Lee SY, Chen A, Lee JH, Kim TW, Alvarez RD, Roden RB, Pardoll D, Hung CF, Wu TC. Kang TH, et al. Cancer Res. 2013 Apr 15;73(8):2493-504. doi: 10.1158/0008-5472.CAN-12-4241. Epub 2013 Feb 15. Cancer Res. 2013. PMID: 23418322 Free PMC article.
In elevating antigen exposure, chemotherapy can achieve long-term control of tumor progression without the need of an additional adjuvant. ...
In elevating antigen exposure, chemotherapy can achieve long-term control of tumor progression without the need of an additional adju …
Cancer vaccination drives Nanog-dependent evolution of tumor cells toward an immune-resistant and stem-like phenotype.
Noh KH, Lee YH, Jeon JH, Kang TH, Mao CP, Wu TC, Kim TW. Noh KH, et al. Among authors: kang th. Cancer Res. 2012 Apr 1;72(7):1717-27. doi: 10.1158/0008-5472.CAN-11-3758. Epub 2012 Feb 14. Cancer Res. 2012. PMID: 22337995 Free PMC article.
However, current data from clinical trials indicate that vaccination rarely yields significant benefits for cancer patients in terms of tumor progression and long-term survival. The poor clinical outcomes of vaccination are primarily caused by mechanisms of immune toleranc …
However, current data from clinical trials indicate that vaccination rarely yields significant benefits for cancer patients in terms of tumo …
Comparison of mesenchymal-like stem/progenitor cells derived from supernumerary teeth with stem cells from human exfoliated deciduous teeth.
Lee S, An S, Kang TH, Kim KH, Chang NH, Kang S, Kwak CK, Park HS. Lee S, et al. Among authors: kang th. Regen Med. 2011 Nov;6(6):689-99. doi: 10.2217/rme.11.95. Regen Med. 2011. PMID: 22050521
CONCLUSION: Both supernumerary teeth and deciduous teeth share many characteristics, such as highly proliferative clonogenic cells with a similar immunophenotype to that of mesenchymal stem cells, although they are inferior to SHED for long-term banking. Our findings sugge …
CONCLUSION: Both supernumerary teeth and deciduous teeth share many characteristics, such as highly proliferative clonogenic cells with a si …
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