A novel function of API5 (apoptosis inhibitor 5), TLR4-dependent activation of antigen presenting cells.
Kim YS, Park HJ, Park JH, Hong EJ, Jang GY, Jung ID, Han HD, Lee SH, Vo MC, Lee JJ, Yang A, Farmer E, Wu TC, Kang TH, Park YM.
Kim YS, et al. Among authors: kang th.
Oncoimmunology. 2018 Aug 15;7(10):e1472187. doi: 10.1080/2162402X.2018.1472187. eCollection 2018.
Oncoimmunology. 2018.
PMID: 30288341
Free PMC article.
We also demonstrated that vaccination with API5-treated DCs pulsed with OVA, E7, or AH1-A5 peptides led to the generation of OVA, E7, or AH1-A5-specific CD8 + T cells and memory T cells, which is associated with long term tumor protection and antitumor effects in mice, aga …
We also demonstrated that vaccination with API5-treated DCs pulsed with OVA, E7, or AH1-A5 peptides led to the generation of OVA, E7, or AH1 …