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Cyclophosphamide reduces gene transcriptional activity and embryo in vitro development by inhibiting NF-κB expression through decreasing AcH4K12.
Luo ZB, Yang LH, Han SZ, Chang SY, Liu H, An ZY, Zhang XL, Quan BH, Yin XJ, Kang JD. Luo ZB, et al. Among authors: kang jd. Chem Biol Interact. 2024 Jan 5;387:110806. doi: 10.1016/j.cbi.2023.110806. Epub 2023 Nov 21. Chem Biol Interact. 2024. PMID: 37980972
Cyclophosphamide (CTX), a widely used chemotherapeutic agent for cancer treatment, has been associated with long-term toxicity and detrimental effects on oocytes and ovaries, resulting in female reproductive dysfunction. ...
Cyclophosphamide (CTX), a widely used chemotherapeutic agent for cancer treatment, has been associated with long-term toxicity and de …
Appropriate Telemedicine Utilization in Spine Surgery: Results From a Delphi Study.
Iyer S, Bovonratwet P, Samartzis D, Schoenfeld AJ, An HS, Awwad W, Blumenthal SL, Cheung JPY, Derman PB, El-Sharkawi M, Freedman BA, Hartl R, Kang JD, Kim HJ, Louie PK, Ludwig SC, Neva MH, Pham MH, Phillips FM, Qureshi SA, Radcliff KE, Riew KD, Sandhu HS, Sciubba DM, Sethi RK, Valacco M, Zaidi HA, Zygourakis CC, Makhni MC. Iyer S, et al. Among authors: kang jd. Spine (Phila Pa 1976). 2022 Apr 15;47(8):583-590. doi: 10.1097/BRS.0000000000004339. Epub 2022 Feb 4. Spine (Phila Pa 1976). 2022. PMID: 35125460
Finally, the panel had consensus that video visits could be appropriate for a variety of visit types including early, midterm, longer term postoperative follow-up, follow-up for imaging review, and follow-up after an intervention (i.e., physical therapy, injection). ...
Finally, the panel had consensus that video visits could be appropriate for a variety of visit types including early, midterm, longer ter
Optimization of compressive loading parameters to mimic in vivo cervical spine kinematics in vitro.
Bell KM, Debski RE, Sowa GA, Kang JD, Tashman S. Bell KM, et al. Among authors: kang jd. J Biomech. 2019 Apr 18;87:107-113. doi: 10.1016/j.jbiomech.2019.02.022. Epub 2019 Mar 7. J Biomech. 2019. PMID: 30905402 Free PMC article.
FL was not necessary at the extremes of the flexion-extension (FE) motion path but peaked through the neutral position, whereas, a large negative value of AL was necessary in extension and increased linearly to a large positive value in flexion. Although further validation is req …
FL was not necessary at the extremes of the flexion-extension (FE) motion path but peaked through the neutral position, whereas, a large neg …
Risk Factors for Prolonged Opioid Use Following Spine Surgery, and the Association with Surgical Intensity, Among Opioid-Naive Patients.
Schoenfeld AJ, Nwosu K, Jiang W, Yau AL, Chaudhary MA, Scully RE, Koehlmoos T, Kang JD, Haider AH. Schoenfeld AJ, et al. Among authors: kang jd. J Bone Joint Surg Am. 2017 Aug 2;99(15):1247-1252. doi: 10.2106/JBJS.16.01075. J Bone Joint Surg Am. 2017. PMID: 28763410
As only 0.1% of the patients continued opioid use at 6 months following surgery, these results indicate that spine surgery among opioid-naive patients is not a major driver of long-term prescription opioid use. Socioeconomic status and pre-existing mental health disorders …
As only 0.1% of the patients continued opioid use at 6 months following surgery, these results indicate that spine surgery among opioid-naiv …
The Evaluation of Donor Site Pain After Harvest of Tricortical Anterior Iliac Crest Bone Graft for Spinal Surgery: A Prospective Study.
Armaghani SJ, Even JL, Zern EK, Braly BA, Kang JD, Devin CJ. Armaghani SJ, et al. Among authors: kang jd. Spine (Phila Pa 1976). 2016 Feb;41(4):E191-6. doi: 10.1097/BRS.0000000000001201. Spine (Phila Pa 1976). 2016. PMID: 26571154
Preoperative opioid use is associated with increased donor site pain within the first 2 weeks postoperatively but not in the long term. At 6 weeks postoperatively, patients can expect the majority of their donor site pain to be resolved. ...
Preoperative opioid use is associated with increased donor site pain within the first 2 weeks postoperatively but not in the long term
Laminoplasty versus laminectomy and fusion for multilevel cervical myelopathy: a meta-analysis of clinical and radiological outcomes.
Lee CH, Lee J, Kang JD, Hyun SJ, Kim KJ, Jahng TA, Kim HJ. Lee CH, et al. Among authors: kang jd. J Neurosurg Spine. 2015 Jun;22(6):589-95. doi: 10.3171/2014.10.SPINE1498. Epub 2015 Mar 27. J Neurosurg Spine. 2015. PMID: 25815808 Review.
Both groups evenly lost cervical lordosis. In the LF group lordosis seemed to be preserved in long-term follow-up studies, although the difference between the 2 treatment groups was not statistically significant. ...Any superiority between EL and LF remains in question, al …
Both groups evenly lost cervical lordosis. In the LF group lordosis seemed to be preserved in long-term follow-up studies, although t …
Valproic acid improved in vitro development of pig cloning embryos but did not improve survival of cloned pigs to adulthood.
Kang JD, Li S, Lu Y, Wang W, Liang S, Liu X, Jin JX, Hong Y, Yan CG, Yin XJ. Kang JD, et al. Theriogenology. 2013 Jan 15;79(2):306-11.e1. doi: 10.1016/j.theriogenology.2012.08.021. Epub 2012 Nov 8. Theriogenology. 2013. PMID: 23140802

The average birth weight of the two litters from the VPA-treated group tended (P < 0.05) to be lower than that from the control groups (551.6 g vs. 675.2 g). In conclusion, VPA treatment increased the blastocyst formation rate of SCNT porcine embryos; both VPA-treated a

The average birth weight of the two litters from the VPA-treated group tended (P < 0.05) to be lower than that from the control gr

Analysis of power law models for the creep of nucleus pulposus tissue.
Agosti CD, Bell KM, Plazek DJ, Larson J, Kang JD, Gilbertson LG, Smolinski P. Agosti CD, et al. Among authors: kang jd. Biorheology. 2010;47(2):143-51. doi: 10.3233/BIR-2010-0564. Biorheology. 2010. PMID: 20683157
Both the Andrade and Nutting creep models had a good fit to the data, however, the Andrade creep model gave a much better prediction of the longer term creep. This is the first application of Andrade creep to biological tissue and results indicate that this model may be pa …
Both the Andrade and Nutting creep models had a good fit to the data, however, the Andrade creep model gave a much better prediction of the …
Donor-site complications of autogenous nonvascularized fibula strut graft harvest for anterior cervical corpectomy and fusion surgery: experience with 163 consecutive cases.
Nassr A, Khan MH, Ali MH, Espiritu MT, Hanks SE, Lee JY, Donaldson WF, Kang JD. Nassr A, et al. Among authors: kang jd. Spine J. 2009 Nov;9(11):893-8. doi: 10.1016/j.spinee.2009.04.020. Epub 2009 Jun 13. Spine J. 2009. PMID: 19525152
RESULTS: One hundred sixty-three patients underwent ACCF with autogenous fibula graft during the study period. The most common short-term complication (lasting <3 months) was incisional pain, present in 86 of 163 patients (53%). ...In this series, most complications wer …
RESULTS: One hundred sixty-three patients underwent ACCF with autogenous fibula graft during the study period. The most common short-term
Does incorrect level needle localization during anterior cervical discectomy and fusion lead to accelerated disc degeneration?
Nassr A, Lee JY, Bashir RS, Rihn JA, Eck JC, Kang JD, Lim MR. Nassr A, et al. Among authors: kang jd. Spine (Phila Pa 1976). 2009 Jan 15;34(2):189-92. doi: 10.1097/BRS.0b013e3181913872. Spine (Phila Pa 1976). 2009. PMID: 19139670
CONCLUSION: There is a 3-fold increase in risk of developing adjacent level disc degeneration in incorrectly marked discs after ACDF at short-term follow-up. This may indicate that either needle related trauma or unnecessary surgical dissection contributes to accelerated a …
CONCLUSION: There is a 3-fold increase in risk of developing adjacent level disc degeneration in incorrectly marked discs after ACDF at shor …
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