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Sex-specific lifetime risk of cardiovascular events: the European Prospective Investigation into Cancer-Norfolk prospective population cohort study.
Pana TA, Mamas MA, Wareham NJ, Khaw KT, Dawson DK, Myint PK. Pana TA, et al. Among authors: khaw kt. Eur J Prev Cardiol. 2024 Jan 25;31(2):230-241. doi: 10.1093/eurjpc/zwad283. Eur J Prev Cardiol. 2024. PMID: 38031203 Free PMC article.
In conclusion, men and women require tailored heart disease prevention efforts given the marked sex disparities in heart disease and death over the very long-term highlighted by our study....
In conclusion, men and women require tailored heart disease prevention efforts given the marked sex disparities in heart disease and death o …
Relationship of Sodium Intake With Granulocytes, Renal and Cardiovascular Outcomes in the Prospective EPIC-Norfolk Cohort.
Wenstedt EFE, Peters Sengers H, Boekholdt SM, Khaw KT, Wareham NJ, van den Born BH, Vogt L. Wenstedt EFE, et al. Among authors: khaw kt. J Am Heart Assoc. 2022 Jul 5;11(13):e023727. doi: 10.1161/JAHA.121.023727. Epub 2022 Jun 22. J Am Heart Assoc. 2022. PMID: 35730648 Free PMC article.
Conclusions Sodium intake is positively associated with circulating granulocyte concentrations, and higher granulocyte concentrations associate with worse long-term cardiovascular and renal outcomes. Given the recently established immune-modulating effects of sodium and th …
Conclusions Sodium intake is positively associated with circulating granulocyte concentrations, and higher granulocyte concentrations associ …
Long-term effects of gestational diabetes on bone mineral density and fracture risk: Analysis of the Norfolk cohort of the European Prospective Investigation into Cancer (EPIC-Norfolk) population-based study.
Ahmeidat A, Bhattacharya S, Luben RN, Khaw KT, Myint PK. Ahmeidat A, et al. Among authors: khaw kt. Maturitas. 2021 Feb;144:68-73. doi: 10.1016/j.maturitas.2020.11.005. Epub 2020 Nov 18. Maturitas. 2021. PMID: 33358211

GDM was significantly (p < 0.05) associated with risk of hip and all fractures, fully adjusted HRs(95 %CI) 2.46(1.54-3.92) and 1.60(1.09-2.35), respectively. Median follow-up from first live birth to date of admission was 53 and 52 years, respectively. CONCLUSION: There

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GDM was significantly (p < 0.05) associated with risk of hip and all fractures, fully adjusted HRs(95 %CI) 2.46(1.54-3.92) and 1.60(1.09-

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Sociodemographic and lifestyle predictors of incident hospital admissions with multimorbidity in a general population, 1999-2019: the EPIC-Norfolk cohort.
Luben R, Hayat S, Wareham N, Pharoah PP, Khaw KT. Luben R, et al. Among authors: khaw kt. BMJ Open. 2020 Sep 22;10(9):e042115. doi: 10.1136/bmjopen-2020-042115. BMJ Open. 2020. PMID: 32963074 Free PMC article.
BACKGROUND: The ageing population and prevalence of long-term disorders with multimorbidity are a major health challenge worldwide. ...
BACKGROUND: The ageing population and prevalence of long-term disorders with multimorbidity are a major health challenge worldwide. . …
Baseline anticholinergic burden from medications predicts poorer baseline and long-term health-related quality of life in 16 675 men and women of EPIC-Norfolk prospective population-based cohort study.
Yrjana KR, Neal SR, Soiza RL, Keevil V, Luben RN, Wareham NJ, Khaw KT, Myint PK. Yrjana KR, et al. Among authors: khaw kt. Pharmacoepidemiol Drug Saf. 2021 Feb;30(2):135-143. doi: 10.1002/pds.5085. Epub 2020 Aug 5. Pharmacoepidemiol Drug Saf. 2021. PMID: 32757254
CONCLUSION: The use of anticholinergic medications is associated with both short and long-term poorer physical functions but association with mental functioning appears more short-term....
CONCLUSION: The use of anticholinergic medications is associated with both short and long-term poorer physical functions but associat …
Menstrual Factors, Reproductive History, Hormone Use, and Urothelial Carcinoma Risk: A Prospective Study in the EPIC Cohort.
Lujan-Barroso L, Botteri E, Caini S, Ljungberg B, Roswall N, Tjønneland A, Bueno-de-Mesquita B, Gram IT, Tumino R, Kiemeney LA, Liedberg F, Stocks T, Gunter MJ, Murphy N, Cervenka I, Fournier A, Kvaskoff M, Häggström C, Overvad K, Lund E, Waaseth M, Fortner RT, Kühn T, Menéndez V, Sánchez MJ, Santiuste C, Perez-Cornago A, Zamora-Ros R, Cross AJ, Trichopoulou A, Karakatsani A, Peppa E, Palli D, Krogh V, Sciannameo V, Mattiello A, Panico S, van Gils CH, Onland-Moret NC, Barricarte A, Amiano P, Khaw KT, Boeing H, Weiderpass E, Duell EJ. Lujan-Barroso L, et al. Among authors: khaw kt. Cancer Epidemiol Biomarkers Prev. 2020 Aug;29(8):1654-1664. doi: 10.1158/1055-9965.EPI-20-0184. Epub 2020 May 28. Cancer Epidemiol Biomarkers Prev. 2020. PMID: 32467345 Free article.
RESULTS: During a mean of 15 years of follow-up, 529 women developed urothelial carcinoma. In a model including number of full-term pregnancies (FTP), menopausal status, and menopausal hormone therapy (MHT), number of FTP was inversely associated with urothelial carcinoma …
RESULTS: During a mean of 15 years of follow-up, 529 women developed urothelial carcinoma. In a model including number of full-term p …
Genomic analysis of male puberty timing highlights shared genetic basis with hair colour and lifespan.
Hollis B, Day FR, Busch AS, Thompson DJ, Soares ALG, Timmers PRHJ, Kwong A, Easton DF, Joshi PK, Timpson NJ; PRACTICAL Consortium; 23andMe Research Team; Ong KK, Perry JRB. Hollis B, et al. Nat Commun. 2020 Mar 24;11(1):1536. doi: 10.1038/s41467-020-14451-5. Nat Commun. 2020. PMID: 32210231 Free PMC article.
The timing of puberty is highly variable and is associated with long-term health outcomes. To date, understanding of the genetic control of puberty timing is based largely on studies in women. ...
The timing of puberty is highly variable and is associated with long-term health outcomes. To date, understanding of the genetic cont …
Association of Long-term Exposure to Elevated Lipoprotein(a) Levels With Parental Life Span, Chronic Disease-Free Survival, and Mortality Risk: A Mendelian Randomization Analysis.
Arsenault BJ, Pelletier W, Kaiser Y, Perrot N, Couture C, Khaw KT, Wareham NJ, Bossé Y, Pibarot P, Stroes ESG, Mathieu P, Thériault S, Boekholdt SM. Arsenault BJ, et al. Among authors: khaw kt. JAMA Netw Open. 2020 Feb 5;3(2):e200129. doi: 10.1001/jamanetworkopen.2020.0129. JAMA Netw Open. 2020. PMID: 32108890 Free PMC article.
OBJECTIVE: To examine whether genetically determined Lp(a) levels are associated with parental life span and chronic disease-free survival (health span) and the association between Lp(a) levels and long-term, all-cause mortality risk. DESIGN, SETTING, AND PARTICIPANTS: In …
OBJECTIVE: To examine whether genetically determined Lp(a) levels are associated with parental life span and chronic disease-free survival ( …
96 results