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Global age-sex-specific mortality, life expectancy, and population estimates in 204 countries and territories and 811 subnational locations, 1950-2021, and the impact of the COVID-19 pandemic: a comprehensive demographic analysis for the Global Burden of Disease Study 2021.
GBD 2021 Demographics Collaborators. GBD 2021 Demographics Collaborators. Lancet. 2024 Mar 8:S0140-6736(24)00476-8. doi: 10.1016/S0140-6736(24)00476-8. Online ahead of print. Lancet. 2024. PMID: 38484753 Free article.
Global life expectancy at birth declined by 1.6 years (1.0-2.2) between 2019 and 2021, reversing historical trends. ...The comprehensive demographic estimates reported here will enable researchers, policy makers, health practitioners, and other key stakeholders to better u …
Global life expectancy at birth declined by 1.6 years (1.0-2.2) between 2019 and 2021, reversing historical trends. ...The comprehens …
Linking Air Pollution Exposure to Blood-Based Metabolic Features in a Community-Based Aging Cohort with and without Dementia.
Kalia V, Kulick ER, Vardarajan B, Gu Y, Manly JJ, Elkind MSV, Kaufman JD, Jones DP, Baccarelli AA, Mayeux R, Kioumourtzoglou MA, Miller GW. Kalia V, et al. Among authors: jones dp. J Alzheimers Dis. 2023;96(3):1025-1040. doi: 10.3233/JAD-230122. J Alzheimers Dis. 2023. PMID: 37927256 Free PMC article.
BACKGROUND: Long-term exposure to air pollution has been associated with changes in levels of metabolites measured in the peripheral blood. ...OBJECTIVE: To study the relationship between the plasma metabolome and long-term exposure to three air pollutants: particul …
BACKGROUND: Long-term exposure to air pollution has been associated with changes in levels of metabolites measured in the peripheral …
Newborn metabolomic signatures of maternal per- and polyfluoroalkyl substance exposure and reduced length of gestation.
Taibl KR, Dunlop AL, Barr DB, Li YY, Eick SM, Kannan K, Ryan PB, Schroder M, Rushing B, Fennell T, Chang CJ, Tan Y, Marsit CJ, Jones DP, Liang D. Taibl KR, et al. Among authors: jones dp. Nat Commun. 2023 May 30;14(1):3120. doi: 10.1038/s41467-023-38710-3. Nat Commun. 2023. PMID: 37253729 Free PMC article.
Marginalized populations experience disproportionate rates of preterm birth and early term birth. Exposure to per- and polyfluoroalkyl substances (PFAS) has been reported to reduce length of gestation, but the underlying mechanisms are unknown. In the present …
Marginalized populations experience disproportionate rates of preterm birth and early term birth. Exposure to per- and …
Metabolite Stability in Archived Neonatal Dried Blood Spots Used for Epidemiologic Research.
He D, Yan Q, Uppal K, Walker DI, Jones DP, Ritz B, Heck JE. He D, et al. Among authors: jones dp. Am J Epidemiol. 2023 Oct 10;192(10):1720-1730. doi: 10.1093/aje/kwad122. Am J Epidemiol. 2023. PMID: 37218607 Free PMC article.
Nicotine metabolites were captured in the DBS with relatively stable intensities. This study supports the usefulness of DBS stored long-term for epidemiologic studies of the metabolome. -Omics-based information gained from DBS may also provide a valuable tool for assessing …
Nicotine metabolites were captured in the DBS with relatively stable intensities. This study supports the usefulness of DBS stored long-t …
Chronic ethanol exposure induces mitochondrial dysfunction and alters gene expression and metabolism in human cardiac spheroids.
Hwang H, Liu R, Eldridge R, Hu X, Forghani P, Jones DP, Xu C. Hwang H, et al. Among authors: jones dp. Alcohol Clin Exp Res (Hoboken). 2023 Apr;47(4):643-658. doi: 10.1111/acer.15026. Epub 2023 Feb 17. Alcohol Clin Exp Res (Hoboken). 2023. PMID: 36799338 Free PMC article.
Prenatal alcohol exposure can increase the risk of developing congenital heart defects among offspring. Understanding the molecular mechanisms underlying long-term alcohol exposure-induced cardiotoxicity can help guide the development of therapeutic strategies. ...
Prenatal alcohol exposure can increase the risk of developing congenital heart defects among offspring. Understanding the molecular mechanis …
Defining roles of specific reactive oxygen species (ROS) in cell biology and physiology.
Sies H, Belousov VV, Chandel NS, Davies MJ, Jones DP, Mann GE, Murphy MP, Yamamoto M, Winterbourn C. Sies H, et al. Among authors: jones dp. Nat Rev Mol Cell Biol. 2022 Jul;23(7):499-515. doi: 10.1038/s41580-022-00456-z. Epub 2022 Feb 21. Nat Rev Mol Cell Biol. 2022. PMID: 35190722 Review.
'Reactive oxygen species' (ROS) is a generic term that defines a wide variety of oxidant molecules with vastly different properties and biological functions that range from signalling to causing cell damage. ...This Expert Recommendation article pinpoints key issues associ …
'Reactive oxygen species' (ROS) is a generic term that defines a wide variety of oxidant molecules with vastly different properties a …
Application of high-resolution metabolomics to identify biological pathways perturbed by traffic-related air pollution.
Li Z, Liang D, Ye D, Chang HH, Ziegler TR, Jones DP, Ebelt ST. Li Z, et al. Among authors: jones dp. Environ Res. 2021 Feb;193:110506. doi: 10.1016/j.envres.2020.110506. Epub 2020 Nov 24. Environ Res. 2021. PMID: 33245887 Free PMC article.
OBJECTIVES: We examined metabolic perturbations associated with short-term exposures to TRAP, including carbon monoxide (CO), nitrogen dioxide (NO(2)), ozone (O(3)), fine particulate matter (PM(2.5)), organic carbon (OC), and elemental carbon (EC) among 180 participants of …
OBJECTIVES: We examined metabolic perturbations associated with short-term exposures to TRAP, including carbon monoxide (CO), nitroge …
Long-term renal function after treatment for unilateral, nonsyndromic Wilms tumor. A report from the St. Jude Lifetime Cohort Study.
Green DM, Wang M, Krasin MJ, Davidoff AM, Srivastava D, Jay DW, Ness KK, Shulkin BL, Spunt SL, Jones DP, Lanctot JQ, Shelton KC, Brennan RC, Mulrooney DA, Ehrhardt MJ, Gibson TM, Kurt BA, Robison LL, Hudson MM. Green DM, et al. Among authors: jones dp. Pediatr Blood Cancer. 2020 Oct;67(10):e28271. doi: 10.1002/pbc.28271. Epub 2020 Jul 24. Pediatr Blood Cancer. 2020. PMID: 32706494 Free PMC article.
BACKGROUND: The impact of specific treatment modalities on long-term renal function and blood pressure among adult survivors of Wilms tumor (WT) has not been well documented. ...Of the 24-hour ambulatory blood pressure monitoring parameters evaluated, only mean sleep perio …
BACKGROUND: The impact of specific treatment modalities on long-term renal function and blood pressure among adult survivors of Wilms …
Reactive oxygen species (ROS) as pleiotropic physiological signalling agents.
Sies H, Jones DP. Sies H, et al. Among authors: jones dp. Nat Rev Mol Cell Biol. 2020 Jul;21(7):363-383. doi: 10.1038/s41580-020-0230-3. Epub 2020 Mar 30. Nat Rev Mol Cell Biol. 2020. PMID: 32231263 Review.
'Reactive oxygen species' (ROS) is an umbrella term for an array of derivatives of molecular oxygen that occur as a normal attribute of aerobic life. ...
'Reactive oxygen species' (ROS) is an umbrella term for an array of derivatives of molecular oxygen that occur as a normal attribute …
Early Pregnancy Serum Metabolite Profiles Associated with Hypertensive Disorders of Pregnancy in African American Women: A Pilot Study.
Ferranti EP, Frediani JK, Mitchell R, Fernandes J, Li S, Jones DP, Corwin E, Dunlop AL. Ferranti EP, et al. Among authors: jones dp. J Pregnancy. 2020 Feb 19;2020:1515321. doi: 10.1155/2020/1515321. eCollection 2020. J Pregnancy. 2020. PMID: 32148965 Free PMC article.
We employed high-resolution metabolomics (HRM) to identify metabolites and metabolic pathways that were altered in early (8-14 weeks) gestation serum samples of pregnant African American women who developed HDP after 20 weeks' gestation (n = 20)-either preeclampsia (PE; n = 11) o …
We employed high-resolution metabolomics (HRM) to identify metabolites and metabolic pathways that were altered in early (8-14 weeks) gestat …
52 results