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Maternal recognition of pregnancy in the pig: A servomechanism involving sex steroids, cytokines and prostaglandins.
Geisert RD, Bazer FW, Lucas CG, Pfeiffer CA, Meyer AE, Sullivan R, Johns DN, Sponchiado M, Prather RS. Geisert RD, et al. Among authors: johns dn. Anim Reprod Sci. 2024 Mar 12;264:107452. doi: 10.1016/j.anireprosci.2024.107452. Online ahead of print. Anim Reprod Sci. 2024. PMID: 38522133 Review.
Maternal recognition of pregnancy (MRP) is a term utilized in mammals to describe pathways in which the conceptus alters the endometrial environment to prevent regression of corpora lutea to ensure continued production of progesterone (P4) required for establishment and ma …
Maternal recognition of pregnancy (MRP) is a term utilized in mammals to describe pathways in which the conceptus alters the endometr …
Novel insights on genetics and epigenetics as clinical targets for paediatric astrocytoma.
Johns DA, Williams RJ, Smith CM, Nadaminti PP, Samarasinghe RM. Johns DA, et al. Clin Transl Med. 2024 Feb;14(2):e1560. doi: 10.1002/ctm2.1560. Clin Transl Med. 2024. PMID: 38299304 Free PMC article. Review.
Paediatric and adult astrocytomas are notably different, where clinical treatments used for adults are not as effective on children with the same form of cancer and these treatments lead to adverse long-term health concerns. Integrative omics-based studies have shown the p …
Paediatric and adult astrocytomas are notably different, where clinical treatments used for adults are not as effective on children with the …
Can We Use Lung Function Thresholds and Respiratory Symptoms to Identify Pre-COPD? A Prospective, Population-based Cohort Study.
Tan DJ, Lodge CJ, Walters EH, Bui DS, Pham J, Lowe AJ, Bowatte G, Vicendese D, Erbas B, Johns DP, James AL, Frith P, Hamilton GS, Thomas PS, Wood-Baker R, Han MK, Washko GR, Abramson MJ, Perret JL, Dharmage SC. Tan DJ, et al. Among authors: johns dp. Am J Respir Crit Care Med. 2024 Jan 18. doi: 10.1164/rccm.202212-2330OC. Online ahead of print. Am J Respir Crit Care Med. 2024. PMID: 38236192
RATIONALE: The term 'pre-COPD' refers to individuals at high-risk of developing Chronic Obstructive Pulmonary Disease (COPD) who do not meet conventional spirometric criteria for airflow obstruction. ...
RATIONALE: The term 'pre-COPD' refers to individuals at high-risk of developing Chronic Obstructive Pulmonary Disease (COPD) who do n …
Understanding Engagement With Forensic Smartphone Apps: The Service Design Engagement Model.
Ross S, Wood MA, Johns D, Murphy J, Baird R, Alford B. Ross S, et al. Among authors: johns d. Int J Offender Ther Comp Criminol. 2022 Jun 22:306624X221106323. doi: 10.1177/0306624X221106323. Online ahead of print. Int J Offender Ther Comp Criminol. 2022. PMID: 35730559
The model recognizes the role of contextual and environmental factors in supporting users through the early stages of engagement, and the importance of user agency in longer-term engagement with therapeutic apps....
The model recognizes the role of contextual and environmental factors in supporting users through the early stages of engagement, and the im …
Evidence of a range expansion in sunfish from 47 years of coastal sightings.
Lyashevska O, Brophy D, Wing S, Johns DG, Haberlin D, Doyle TK. Lyashevska O, et al. Among authors: johns dg. Mar Biol. 2022;169(2):20. doi: 10.1007/s00227-021-04005-8. Epub 2022 Jan 13. Mar Biol. 2022. PMID: 35221377 Free PMC article.
Within this context, sightings from a coastal bird observatory (51.26 N, 9.30 W) over a 47 year period (from April to October 1971-2017) provided the first long-term index of sunfish abundance. Using a general linear mixed effect model with a hurdle to deal with imperfect …
Within this context, sightings from a coastal bird observatory (51.26 N, 9.30 W) over a 47 year period (from April to October 1971-2017) pro …
Association between very to moderate preterm births, lung function deficits, and COPD at age 53 years: analysis of a prospective cohort study.
Bui DS, Perret JL, Walters EH, Lodge CJ, Bowatte G, Hamilton GS, Thompson BR, Frith P, Erbas B, Thomas PS, Johns DP, Wood-Baker R, Hopper JL, Davis PG, Abramson MJ, Lowe AJ, Dharmage SC. Bui DS, et al. Among authors: johns dp. Lancet Respir Med. 2022 May;10(5):478-484. doi: 10.1016/S2213-2600(21)00508-7. Epub 2022 Feb 18. Lancet Respir Med. 2022. PMID: 35189074
RESULTS: Of 3565 individuals with available data on gestational age from the TAHS cohort, 1445 (41%) participants were included in this study, 740 (51%) of whom were female. Compared with term birth, very to moderate preterm birth was significantly associated …
RESULTS: Of 3565 individuals with available data on gestational age from the TAHS cohort, 1445 (41%) participants were included in this stud …
Gene editing to investigate the role of conceptus factors in the establishment of pregnancy in the pig.
Geisert RD, Meyer AE, Pfeiffer CA, Johns DN, Lee K, Wells KD, Spencer TE, Prather RS. Geisert RD, et al. Among authors: johns dn. Reproduction. 2021 Apr;161(4):R79-R88. doi: 10.1530/REP-20-0604. Reproduction. 2021. PMID: 33560267 Review.
In addition to the retention of the fetus and secretion of nutrients to support growth and development to term, it is essential that viviparous species modify or inhibit the maternal immune system from recognizing the semi-allogeneic fetus. ...
In addition to the retention of the fetus and secretion of nutrients to support growth and development to term, it is essential that …
Lifeform indicators reveal large-scale shifts in plankton across the North-West European shelf.
Bedford J, Ostle C, Johns DG, Atkinson A, Best M, Bresnan E, Machairopoulou M, Graves CA, Devlin M, Milligan A, Pitois S, Mellor A, Tett P, McQuatters-Gollop A. Bedford J, et al. Among authors: johns dg. Glob Chang Biol. 2020 Jun;26(6):3482-3497. doi: 10.1111/gcb.15066. Epub 2020 Apr 1. Glob Chang Biol. 2020. PMID: 32237280
For the first time, we collate trends across multiple disparate surveys, comparing the spatially and temporally extensive Continuous Plankton Recorder (CPR) survey (offshore) with multiple long-term fixed station-based time-series (inshore) from around the UK coastline. Th …
For the first time, we collate trends across multiple disparate surveys, comparing the spatially and temporally extensive Continuous Plankto …
Impact of drug distribution into adipose on tissue function: The cholesteryl ester transfer protein (CETP) inhibitor anacetrapib as a test case.
Johns DG, Wang SP, Rosa R, Hubert J, Xu S, Chen Y, Bateman T, Blaustein RO. Johns DG, et al. Pharmacol Res Perspect. 2019 Nov 15;7(6):e00543. doi: 10.1002/prp2.543. eCollection 2019 Dec. Pharmacol Res Perspect. 2019. PMID: 31832204 Free PMC article.
In DIO wild-type (WT) mice treated with anacetrapib for 2 weeks and then subjected to 30% food restriction during washout to induce weight loss (18%) and fat mass loss (7%), levels of anacetrapib in adipose and plasma were not different between food restricted and ad lib-fed mice …
In DIO wild-type (WT) mice treated with anacetrapib for 2 weeks and then subjected to 30% food restriction during washout to induce weight l …
54 results