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Oxidative stress: an evolving definition.
Ji LL, Yeo D. Ji LL, et al. Fac Rev. 2021 Feb 9;10:13. doi: 10.12703/r/10-13. eCollection 2021. Fac Rev. 2021. PMID: 33659931 Free PMC article. Review.
Thirty-five years ago, Sies and colleagues insightfully described the universal phenomenon that the generation of reactive oxygen species could modify macromolecules in living organisms, resulting in a wide range of measurable damage. They used the term "oxidative stress" …
Thirty-five years ago, Sies and colleagues insightfully described the universal phenomenon that the generation of reactive oxygen species co …
[A case of gout secondary to primary myelofibrosis].
Ji LL, Hao YJ, Zhang ZL. Ji LL, et al. Beijing Da Xue Xue Bao Yi Xue Ban. 2018 Dec 18;50(6):1117-1119. Beijing Da Xue Xue Bao Yi Xue Ban. 2018. PMID: 30562793 Free article. Chinese.
This patient only had one traditional risk factor, but his urate acid level was remarkably high and he developed tophus in a short term. After treatment of primary myelofibrosis, the symptom of gout partially alleviated. ...
This patient only had one traditional risk factor, but his urate acid level was remarkably high and he developed tophus in a short term …
Avenanthramide supplementation attenuates eccentric exercise-inflicted blood inflammatory markers in women.
Koenig RT, Dickman JR, Kang CH, Zhang T, Chu YF, Ji LL. Koenig RT, et al. Among authors: ji ll. Eur J Appl Physiol. 2016 Jan;116(1):67-76. doi: 10.1007/s00421-015-3244-3. Epub 2015 Aug 20. Eur J Appl Physiol. 2016. PMID: 26289619 Clinical Trial.
CONCLUSIONS: Our data of pre- and post-supplementation difference reflect an interaction between repeated measure effect of eccentric exercise and AVA in diet. Long-term AVA supplementation can attenuate blood inflammation markers, decrease ROS generation and NFkB activati …
CONCLUSIONS: Our data of pre- and post-supplementation difference reflect an interaction between repeated measure effect of eccentric exerci …
Exercise-induced neuroprotection of hippocampus in APP/PS1 transgenic mice via upregulation of mitochondrial 8-oxoguanine DNA glycosylase.
Bo H, Kang W, Jiang N, Wang X, Zhang Y, Ji LL. Bo H, et al. Among authors: ji ll. Oxid Med Cell Longev. 2014;2014:834502. doi: 10.1155/2014/834502. Epub 2014 Nov 5. Oxid Med Cell Longev. 2014. PMID: 25538817 Free PMC article.
This study was undertaken to investigate the effects of long-term treadmill exercise on mitochondrial 8-oxoguanine DNA glycosylase-1 (OGG1) level, mtDNA oxidative damage, and mitochondrial function in the hippocampus of APP/PS1 transgenic mouse model of AD. ...
This study was undertaken to investigate the effects of long-term treadmill exercise on mitochondrial 8-oxoguanine DNA glycosylase-1 …
Intra-hippocampal administration of ZIP alleviates depressive and anxiety-like responses in an animal model of posttraumatic stress disorder.
Ji LL, Tong L, Xu BK, Fu CH, Shu W, Peng JB, Wang ZY. Ji LL, et al. Behav Brain Funct. 2014 Sep 1;10:28. doi: 10.1186/1744-9081-10-28. Behav Brain Funct. 2014. PMID: 25178800 Free PMC article.
It is generally accepted that the zeta inhibitory peptide (ZIP), a controversial inhibitor of protein kinase M zeta (PKMzeta), could erase certain types of previously established long-term memories. However, it is unclear whether ZIP administration may alleviate PTSD-assoc …
It is generally accepted that the zeta inhibitory peptide (ZIP), a controversial inhibitor of protein kinase M zeta (PKMzeta), could erase c …
Role of nuclear factor kappaB and mitogen-activated protein kinase signaling in exercise-induced antioxidant enzyme adaptation.
Ji LL, Gomez-Cabrera MC, Vina J. Ji LL, et al. Appl Physiol Nutr Metab. 2007 Oct;32(5):930-5. doi: 10.1139/H07-098. Appl Physiol Nutr Metab. 2007. PMID: 18059618 Review.
Thus, ROS generation during exercise may have duel effects: the infliction of oxidative stress and damage, and the stimulation of adaptive responses favoring long-term protection. This scenario explains why animals and humans involved in exercise training have demonstrated …
Thus, ROS generation during exercise may have duel effects: the infliction of oxidative stress and damage, and the stimulation of adaptive r …
Sleep deprivation and cellular responses to oxidative stress.
Gopalakrishnan A, Ji LL, Cirelli C. Gopalakrishnan A, et al. Among authors: ji ll. Sleep. 2004 Feb 1;27(1):27-35. doi: 10.1093/sleep/27.1.27. Sleep. 2004. PMID: 14998234
DESIGN: The analyses were performed in the brain and in peripheral tissues (liver and skeletal muscle), after short-term sleep deprivation (8 hours), after long-term sleep deprivation (3-14 days), and during recovery sleep after 1 week of sleep loss. Short-term …
DESIGN: The analyses were performed in the brain and in peripheral tissues (liver and skeletal muscle), after short-term sleep depriv …
Exercise training reduces myocardial lipid peroxidation following short-term ischemia-reperfusion.
Demirel HA, Powers SK, Caillaud C, Coombes JS, Naito H, Fletcher LA, Vrabas I, Jessup JV, Ji LL. Demirel HA, et al. Among authors: ji ll. Med Sci Sports Exerc. 1998 Aug;30(8):1211-6. doi: 10.1097/00005768-199808000-00005. Med Sci Sports Exerc. 1998. PMID: 9710859
PURPOSE: The purpose of these experiments was to test the hypothesis that endurance exercise training will reduce myocardial lipid peroxidation following short-term ischemia and reperfusion (I-R). METHODS: Female Sprague-Dawley rats (4 months old) were randomly assigned to …
PURPOSE: The purpose of these experiments was to test the hypothesis that endurance exercise training will reduce myocardial lipid peroxidat …
Ischaemia-reperfusion induced alterations of mitochondrial function in hypertrophied rat heart.
Leichtweis SB, Leeuwenburgh C, Chandwaney R, Parmelee DJ, Ji LL. Leichtweis SB, et al. Among authors: ji ll. Acta Physiol Scand. 1996 Jan;156(1):51-60. doi: 10.1046/j.1365-201X.1996.427148000.x. Acta Physiol Scand. 1996. PMID: 8866886
Malondialdehyde content showed an increase with I-R, but the increase was significant only in control hearts. These data indicate that short-term in vivo I-R does not impair heart mitochondrial respiratory function, but renders the organelles more vulnerable to imposed oxi …
Malondialdehyde content showed an increase with I-R, but the increase was significant only in control hearts. These data indicate that short …