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Tad Pili Play a Dynamic Role in Caulobacter crescentus Surface Colonization.
Sangermani M, Hug I, Sauter N, Pfohl T, Jenal U. Sangermani M, et al. Among authors: jenal u. mBio. 2019 Jun 18;10(3):e01237-19. doi: 10.1128/mBio.01237-19. mBio. 2019. PMID: 31213565 Free PMC article.
Pilus-mediated positioning of the flagellate pole close to the surface facilitates motor-mediated mechanical sensing and promotes anchoring of the holdfast, an adhesive substance that affords long-term attachment. We present evidence that the second messenger c-di-GMP regu …
Pilus-mediated positioning of the flagellate pole close to the surface facilitates motor-mediated mechanical sensing and promotes anchoring …
The YfiBNR signal transduction mechanism reveals novel targets for the evolution of persistent Pseudomonas aeruginosa in cystic fibrosis airways.
Malone JG, Jaeger T, Manfredi P, Dötsch A, Blanka A, Bos R, Cornelis GR, Häussler S, Jenal U. Malone JG, et al. Among authors: jenal u. PLoS Pathog. 2012;8(6):e1002760. doi: 10.1371/journal.ppat.1002760. Epub 2012 Jun 14. PLoS Pathog. 2012. PMID: 22719254 Free PMC article.
While whole genome sequencing has opened up the analysis of genetic changes occurring during long-term infections, the identification and characterization of adaptive traits is often obscured by a lack of knowledge of the underlying molecular processes. Our research addres …
While whole genome sequencing has opened up the analysis of genetic changes occurring during long-term infections, the identification …
YfiBNR mediates cyclic di-GMP dependent small colony variant formation and persistence in Pseudomonas aeruginosa.
Malone JG, Jaeger T, Spangler C, Ritz D, Spang A, Arrieumerlou C, Kaever V, Landmann R, Jenal U. Malone JG, et al. Among authors: jenal u. PLoS Pathog. 2010 Mar 12;6(3):e1000804. doi: 10.1371/journal.ppat.1000804. PLoS Pathog. 2010. PMID: 20300602 Free PMC article.
During long-term cystic fibrosis lung infections, Pseudomonas aeruginosa undergoes genetic adaptation resulting in progressively increased persistence and the generation of adaptive colony morphotypes. ...
During long-term cystic fibrosis lung infections, Pseudomonas aeruginosa undergoes genetic adaptation resulting in progressively incr …