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Which severe COVID-19 patients could benefit from high dose dexamethasone? A Bayesian post-hoc reanalysis of the COVIDICUS randomized clinical trial.
Chevret S, Bouadma L, Dupuis C, Burdet C, Timsit JF; COVIDICUS RCT group. Chevret S, et al. Ann Intensive Care. 2023 Aug 27;13(1):75. doi: 10.1186/s13613-023-01168-z. Ann Intensive Care. 2023. PMID: 37634234 Free PMC article.
TRIAL REGISTRATION: NCT04344730, date of registration April 14, 2020 ( https://clinicaltrials.gov/ct2/show/NCT04344730?term=NCT04344730&draw=2&rank=1 ); EudraCT: 2020-001457-43 ( https://www.clinicaltrialsregister.eu/ctr-search/search?...
TRIAL REGISTRATION: NCT04344730, date of registration April 14, 2020 ( https://clinicaltrials.gov/ct2/show/NCT04344730?term=NCT043447 …
PupillOmetry for preDIction of DeliriUM in ICU (PODIUM): protocol for a prospective multicentre cohort study.
Jaquet P, Couffignal C, Tardivon C, Godard V, Bellot R, Assouline B, Benghanem S, Da Silva D, Decavèle M, Dessajan J, Hermann B, Rambaud T, Voiriot G, Sonneville R; PODIUM Study Group. Jaquet P, et al. BMJ Open. 2023 Jul 12;13(7):e072095. doi: 10.1136/bmjopen-2023-072095. BMJ Open. 2023. PMID: 37438060 Free PMC article.
INTRODUCTION: Delirium is a severe complication that is associated with short-term adverse events, prolonged hospital stay and neurological sequelae in survivors. ...
INTRODUCTION: Delirium is a severe complication that is associated with short-term adverse events, prolonged hospital stay and neurol …
One-Year Mental and Physical Health Assessment in Survivors after Extracorporeal Membrane Oxygenation for COVID-19-related Acute Respiratory Distress Syndrome.
Chommeloux J, Valentin S, Winiszewski H, Adda M, Pineton de Chambrun M, Moyon Q, Mathian A, Capellier G, Guervilly C, Levy B, Jaquet P, Sonneville R, Voiriot G, Demoule A, Boussouar S, Painvin B, Lebreton G, Combes A, Schmidt M. Chommeloux J, et al. Among authors: jaquet p. Am J Respir Crit Care Med. 2023 Jan 15;207(2):150-159. doi: 10.1164/rccm.202206-1145OC. Am J Respir Crit Care Med. 2023. PMID: 36150112 Free PMC article.
Rationale: Long-term outcomes of patients with coronavirus disease (COVID-19)-related acute respiratory distress syndrome treated with extracorporeal membrane oxygenation (ECMO) are unknown. ...Conclusions: Despite the partial recovery of the lung function tests at 1 year, …
Rationale: Long-term outcomes of patients with coronavirus disease (COVID-19)-related acute respiratory distress syndrome treated wit …
Neurologic Outcomes of Survivors of COVID-19-Associated Acute Respiratory Distress Syndrome Requiring Intubation.
Jaquet P, Legouy C, Le Fevre L, Grinea A, Sinnah F, Franchineau G, Patrier J, Marzouk M, Wicky PH, Alexis Geoffroy P, Arnoult F, Vledouts S, de Montmollin E, Bouadma L, Timsit JF, Sharshar T, Sonneville R. Jaquet P, et al. Crit Care Med. 2022 Aug 1;50(8):e674-e682. doi: 10.1097/CCM.0000000000005500. Epub 2022 Feb 8. Crit Care Med. 2022. PMID: 35132020 Free PMC article.
A large multicenter study is warranted to allow identification of modifiable factors for improving long-term outcome....
A large multicenter study is warranted to allow identification of modifiable factors for improving long-term outcome....
Intensive care management of patients with viral encephalitis.
Sonneville R, Jaquet P, Vellieux G, de Montmollin E, Visseaux B. Sonneville R, et al. Among authors: jaquet p. Rev Neurol (Paris). 2022 Jan-Feb;178(1-2):48-56. doi: 10.1016/j.neurol.2021.12.002. Epub 2021 Dec 29. Rev Neurol (Paris). 2022. PMID: 34973832 Review.
Large prospective multicenter studies combining clinical, electrophysiological, and neuroimaging data are needed to improve current knowledge on care pathways, long-term outcomes, and prognostication....
Large prospective multicenter studies combining clinical, electrophysiological, and neuroimaging data are needed to improve current knowledg …
Cell growth inhibition and functioning of human somatostatin receptor type 2 are modulated by receptor heterodimerization.
Grant M, Alturaihi H, Jaquet P, Collier B, Kumar U. Grant M, et al. Among authors: jaquet p. Mol Endocrinol. 2008 Oct;22(10):2278-92. doi: 10.1210/me.2007-0334. Epub 2008 Jul 24. Mol Endocrinol. 2008. PMID: 18653781 Free PMC article.
Given that SST analogs show preferential binding to SSTR2, these data provide a mechanism for their effectiveness in controlling pituitary tumors and the absence of tolerance seen in patients undergoing long-term administration....
Given that SST analogs show preferential binding to SSTR2, these data provide a mechanism for their effectiveness in controlling pituitary t …
Ketoconazole revisited: a preoperative or postoperative treatment in Cushing's disease.
Castinetti F, Morange I, Jaquet P, Conte-Devolx B, Brue T. Castinetti F, et al. Among authors: jaquet p. Eur J Endocrinol. 2008 Jan;158(1):91-9. doi: 10.1530/EJE-07-0514. Eur J Endocrinol. 2008. PMID: 18166822
Despite its inhibitory effects on steroidogenesis, the antifungal drug ketoconazole was only evaluated in series with few patients and/or short-term follow-up. OBJECTIVE: Analysis of long-term hormonal effects and tolerance of ketoconazole in CD. ...On an intention …
Despite its inhibitory effects on steroidogenesis, the antifungal drug ketoconazole was only evaluated in series with few patients and/or sh …
Gamma knife radiosurgery is a successful adjunctive treatment in Cushing's disease.
Castinetti F, Nagai M, Dufour H, Kuhn JM, Morange I, Jaquet P, Conte-Devolx B, Regis J, Brue T. Castinetti F, et al. Among authors: jaquet p. Eur J Endocrinol. 2007 Jan;156(1):91-8. doi: 10.1530/eje.1.02323. Eur J Endocrinol. 2007. PMID: 17218730
Stereotactic radiosurgery needs to be evaluated more precisely. The aim of this study was to determine long-term hormonal effects and tolerance of gamma knife (GK) radiosurgery in Cushing's disease. ...
Stereotactic radiosurgery needs to be evaluated more precisely. The aim of this study was to determine long-term hormonal effects and …
BIM-23A760, a chimeric molecule directed towards somatostatin and dopamine receptors, vs universal somatostatin receptors ligands in GH-secreting pituitary adenomas partial responders to octreotide.
Jaquet P, Gunz G, Saveanu A, Barlier A, Dufour H, Taylor J, Dong J, Kim S, Moreau JP, Culler MD. Jaquet P, et al. J Endocrinol Invest. 2005;28(11 Suppl International):21-7. J Endocrinol Invest. 2005. PMID: 16625841
We report the comparative efficacy of a somatostatin receptor 1 and 5 subtypes (SSTR2 and SSTR5), and dopamine D2 (DAD2) compound, BIM-23A760, in suppressing GH secretion, in cell culture from human GH-secreting tumors, from patients partially responsive to long-term treat …
We report the comparative efficacy of a somatostatin receptor 1 and 5 subtypes (SSTR2 and SSTR5), and dopamine D2 (DAD2) compound, BIM-23A76 …
Quinagolide--a valuable treatment option for hyperprolactinaemia.
Barlier A, Jaquet P. Barlier A, et al. Among authors: jaquet p. Eur J Endocrinol. 2006 Feb;154(2):187-95. doi: 10.1530/eje.1.02075. Eur J Endocrinol. 2006. PMID: 16452531 Review.
Hyperprolactinaemia is characterised by gonadal dysfunction, including infertility and reduced libido and, if left untreated, is associated with an increased risk of long-term complications, such as osteoporosis. The first-line therapy for patients with hyperprolactinaemia …
Hyperprolactinaemia is characterised by gonadal dysfunction, including infertility and reduced libido and, if left untreated, is associated …
34 results