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Lipoprotein(a) and Major Adverse Cardiovascular Events in Patients With or Without Baseline Atherosclerotic Cardiovascular Disease.
Berman AN, Biery DW, Besser SA, Singh A, Shiyovich A, Weber BN, Huck DM, Divakaran S, Hainer J, Kaur G, Blaha MJ, Cannon CP, Plutzky J, Januzzi JL, Booth JN 3rd, López JAG, Kent ST, Nasir K, Di Carli MF, Bhatt DL, Blankstein R. Berman AN, et al. Among authors: januzzi jl. J Am Coll Cardiol. 2024 Mar 5;83(9):873-886. doi: 10.1016/j.jacc.2023.12.031. J Am Coll Cardiol. 2024. PMID: 38418000
CONCLUSIONS: In a large, contemporary U.S. cohort, elevated Lp(a) is independently associated with long-term MACE among individuals with and without baseline ASCVD. Our results suggest that the threshold for risk assessment may be different in primary vs secondary preventi …
CONCLUSIONS: In a large, contemporary U.S. cohort, elevated Lp(a) is independently associated with long-term MACE among individuals w …
Genetic Associations of Circulating Cardiovascular Proteins With Gestational Hypertension and Preeclampsia.
Schuermans A, Truong B, Ardissino M, Bhukar R, Slob EAW, Nakao T, Dron JS, Small AM, Cho SMJ, Yu Z, Hornsby W, Antoine T, Lannery K, Postupaka D, Gray KJ, Yan Q, Butterworth AS, Burgess S, Wood MJ, Scott NS, Harrington CM, Sarma AA, Lau ES, Roh JD, Januzzi JL Jr, Natarajan P, Honigberg MC. Schuermans A, et al. Among authors: januzzi jl jr. JAMA Cardiol. 2024 Mar 1;9(3):209-220. doi: 10.1001/jamacardio.2023.4994. JAMA Cardiol. 2024. PMID: 38170504 Free PMC article.
IMPORTANCE: Hypertensive disorders of pregnancy (HDPs), including gestational hypertension and preeclampsia, are important contributors to maternal morbidity and mortality worldwide. In addition, women with HDPs face an elevated long-term risk of cardiovascular disease. OB …
IMPORTANCE: Hypertensive disorders of pregnancy (HDPs), including gestational hypertension and preeclampsia, are important contributors to m …
Bridging Treatment Implementation Gaps in Patients With Heart Failure: JACC Focus Seminar 2/3.
Jalloh MB, Averbuch T, Kulkarni P, Granger CB, Januzzi JL, Zannad F, Yeh RW, Yancy CW, Fonarow GC, Breathett K, Gibson CM, Van Spall HGC. Jalloh MB, et al. Among authors: januzzi jl. J Am Coll Cardiol. 2023 Aug 8;82(6):544-558. doi: 10.1016/j.jacc.2023.05.050. J Am Coll Cardiol. 2023. PMID: 37532425 Free article. Review.
We propose an evidence-to-care conceptual model that could foster the simultaneous generation of evidence and long-term implementation. By adopting principles of implementation science, policymakers, researchers, and clinicians can help reduce the burden of HF on patients …
We propose an evidence-to-care conceptual model that could foster the simultaneous generation of evidence and long-term implementatio …
Multiple Biomarkers to Predict Major Adverse Cardiovascular Events in Patients With Coronary Chronic Total Occlusions.
Adusumalli S, Mohebi R, McCarthy CP, Megaret CA, Rhyne RF, Jaffer FA, Januzzi JL. Adusumalli S, et al. Among authors: januzzi jl. medRxiv [Preprint]. 2023 Jul 23:2023.07.19.23292911. doi: 10.1101/2023.07.19.23292911. medRxiv. 2023. PMID: 37503157 Free PMC article. Preprint.
BACKGROUND: There are limited tools available to predict the long-term prognosis of persons with coronary chronic total occlusions (CTO). ...
BACKGROUND: There are limited tools available to predict the long-term prognosis of persons with coronary chronic total occlusions (C …
Morbidity and Mortality Associated With Heart Failure in Acute Coronary Syndrome: A Pooled Analysis of 4 Clinical Trials.
Goodwin NP, Clare RM, Harrington JL, Badjatiya A, Wojdyla DM, Udell JA, Butler J, Januzzi JL Jr, Parikh PB, James S, Alexander JH, Lopes RD, Wallentin L, Ohman EM, Hernandez AF, Jones WS. Goodwin NP, et al. Among authors: januzzi jl jr. J Card Fail. 2023 Dec;29(12):1603-1614. doi: 10.1016/j.cardfail.2023.07.004. Epub 2023 Jul 20. J Card Fail. 2023. PMID: 37479054
BACKGROUND: Heart failure (HF) may complicate acute coronary syndrome (ACS) and is associated with a high burden of short- and long-term morbidity and mortality. Only limited data regarding future ischemic events and rehospitalization are available for patients who suffer …
BACKGROUND: Heart failure (HF) may complicate acute coronary syndrome (ACS) and is associated with a high burden of short- and long-term …
Twenty-five years of observations from the International Registry of Acute Aortic Dissection (IRAD) and its impact on the cardiovascular scientific community.
Trimarchi S, Mandigers TJ, Bissacco D, Nienaber C, Isselbacher EM, Evangelista A, Suzuki T, Bossone E, Pape LA, Januzzi JL, Harris KM, O'Gara PT, Gilon D, Hutchison S, Patel HJ, Woznicki EM, Montgomery D, Kline-Rogers E, Eagle KA. Trimarchi S, et al. Among authors: januzzi jl. J Thorac Cardiovasc Surg. 2023 Jul 13:S0022-5223(23)00608-6. doi: 10.1016/j.jtcvs.2023.06.021. Online ahead of print. J Thorac Cardiovasc Surg. 2023. PMID: 37453718
Of these studies, most investigated both type A and type B AD (n = 17, 40.5%) and short-term outcomes (n = 26, 61.9%). Nineteen guideline documents were identified from 26 cardiovascular societies located in Northern America, Europe, and Japan. ...
Of these studies, most investigated both type A and type B AD (n = 17, 40.5%) and short-term outcomes (n = 26, 61.9%). Nineteen guide …
Cardiac remodelling - Part 1: From cells and tissues to circulating biomarkers. A review from the Study Group on Biomarkers of the Heart Failure Association of the European Society of Cardiology.
González A, Richards AM, de Boer RA, Thum T, Arfsten H, Hülsmann M, Falcao-Pires I, Díez J, Foo RSY, Chan MY, Aimo A, Anene-Nzelu CG, Abdelhamid M, Adamopoulos S, Anker SD, Belenkov Y, Ben Gal T, Cohen-Solal A, Böhm M, Chioncel O, Delgado V, Emdin M, Jankowska EA, Gustafsson F, Hill L, Jaarsma T, Januzzi JL, Jhund PS, Lopatin Y, Lund LH, Metra M, Milicic D, Moura B, Mueller C, Mullens W, Núñez J, Piepoli MF, Rakisheva A, Ristić AD, Rossignol P, Savarese G, Tocchetti CG, Van Linthout S, Volterrani M, Seferovic P, Rosano G, Coats AJS, Bayés-Genís A. González A, et al. Among authors: januzzi jl. Eur J Heart Fail. 2022 Jun;24(6):927-943. doi: 10.1002/ejhf.2493. Epub 2022 Apr 21. Eur J Heart Fail. 2022. PMID: 35334137 Free article. Review.
The geometry, systolic and diastolic function and electric activity of the left ventricle are affected, as well as the left atrium and on the long term even right heart chambers. At a cellular and molecular level, remodelling involves all components of cardiac tissue: card …
The geometry, systolic and diastolic function and electric activity of the left ventricle are affected, as well as the left atrium and on th …
Stress Cardiac Biomarkers, Cardiovascular and Renal Outcomes, and Response to Canagliflozin.
Vaduganathan M, Sattar N, Xu J, Butler J, Mahaffey KW, Neal B, Shaw W, Rosenthal N, Pfeifer M, Hansen MK, Januzzi JL Jr. Vaduganathan M, et al. Among authors: januzzi jl jr. J Am Coll Cardiol. 2022 Feb 8;79(5):432-444. doi: 10.1016/j.jacc.2021.11.027. J Am Coll Cardiol. 2022. PMID: 35115099 Free PMC article. Clinical Trial.
METHODS: In the CANVAS (CANagliflozin cardioVascular Assessment Study) biomarker substudy, we evaluated the prognostic significance of baseline biomarker measurements, the long-term trajectory of each, and response to canagliflozin on key cardiovascular and kidney outcomes …
METHODS: In the CANVAS (CANagliflozin cardioVascular Assessment Study) biomarker substudy, we evaluated the prognostic significance of basel …
Retrospective analysis of arterial occlusive events in the PACE trial by an independent adjudication committee.
Januzzi JL, Garasic JM, Kasner SE, McDonald V, Petrie MC, Seltzer J, Mauro M, Croce K, Berman E, Deininger M, Hochhaus A, Pinilla-Ibarz J, Nicolini F, Kim DW, DeAngelo DJ, Kantarjian H, Xu J, Hall T, Srivastava S, Naranjo D, Cortes J. Januzzi JL, et al. J Hematol Oncol. 2022 Jan 6;15(1):1. doi: 10.1186/s13045-021-01221-z. J Hematol Oncol. 2022. PMID: 34991679 Free PMC article. Clinical Trial.
BACKGROUND: The phase 2 PACE (Ponatinib Ph+ ALL and CML Evaluation) trial of ponatinib showed robust long-term benefit in relapsed Philadelphia chromosome-positive (Ph+) leukemia; arterial occlusive events (AOEs) occurred in 25% of patients based on investigator reporting. …
BACKGROUND: The phase 2 PACE (Ponatinib Ph+ ALL and CML Evaluation) trial of ponatinib showed robust long-term benefit in relapsed Ph …
Multiple Cardiac Biomarker Testing Among Patients With Acute Dyspnea From the ICON-RELOADED Study.
Abboud A, Kui N, Gaggin HK, Ibrahim NE, Chen-Tournoux AA, Christenson RH, Hollander JE, Levy PD, Nagurney JT, Nowak RM, Pang PS, Peacock WF, Walters EL, Januzzi JL. Abboud A, et al. Among authors: januzzi jl. J Card Fail. 2022 Feb;28(2):226-233. doi: 10.1016/j.cardfail.2021.08.025. Epub 2021 Oct 9. J Card Fail. 2022. PMID: 34634446 Free article.
Differences in the number of elevated biomarkers at presentation may allow for more efficient clinical risk stratification of short-term mortality and HF rehospitalization....
Differences in the number of elevated biomarkers at presentation may allow for more efficient clinical risk stratification of short-term …
74 results