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Neoadjuvant chemotherapy is associated with suppression of the B cell-centered immune landscape in pancreatic ductal adenocarcinoma.
Rupp L, Dietsche I, Kießler M, Sommer U, Muckenhuber A, Steiger K, van Eijck CWF, Richter L, Istvanffy R, Jäger C, Friess H, van Eijck CHJ, Demir IE, Reyes CM, Schmitz M. Rupp L, et al. Among authors: jager c. Front Immunol. 2024 Apr 2;15:1378190. doi: 10.3389/fimmu.2024.1378190. eCollection 2024. Front Immunol. 2024. PMID: 38629072 Free PMC article.
Gaining further insight into the underlying molecular mechanisms is crucial to overcome the intrinsic immunotherapy resistance of PDAC and develop novel strategies to improve the long-term outcome of PDAC patients....
Gaining further insight into the underlying molecular mechanisms is crucial to overcome the intrinsic immunotherapy resistance of PDAC and d …
The Association between Long-Term DDT or DDE Exposures and an Altered Sperm Epigenome-a Cross-Sectional Study of Greenlandic Inuit and South African VhaVenda Men.
Lismer A, Shao X, Dumargne MC, Lafleur C, Lambrot R, Chan D, Toft G, Bonde JP, MacFarlane AJ, Bornman R, Aneck-Hahn N, Patrick S, Bailey JM, de Jager C, Dumeaux V, Trasler JM, Kimmins S. Lismer A, et al. Among authors: de jager c. Environ Health Perspect. 2024 Jan;132(1):17008. doi: 10.1289/EHP12013. Epub 2024 Jan 31. Environ Health Perspect. 2024. PMID: 38294233 Free PMC article.
Exposure occurs in regions where DDT is applied, as well as in the Arctic, where its endocrine disrupting metabolite, p, p'-dichlorodiphenyldichloroethylene (p, p'-DDE) accumulates in marine mammals and fish. DDT and p, p'-DDE exposures are linked to birth defects, inferti …
Exposure occurs in regions where DDT is applied, as well as in the Arctic, where its endocrine disrupting metabolite, p, p'-dichlorodiphenyl …
Dynamic prediction of mortality in COVID-19 patients in the intensive care unit: A retrospective multi-center cohort study.
Smit JM, Krijthe JH, Endeman H, Tintu AN, de Rijke YB, Gommers DAMPJ, Cremer OL, Bosman RJ, Rigter S, Wils EJ, Frenzel T, Dongelmans DA, De Jong R, Peters MAA, Kamps MJA, Ramnarain D, Nowitzky R, Nooteboom FGCA, De Ruijter W, Urlings-Strop LC, Smit EGM, Mehagnoul-Schipper DJ, Dormans T, De Jager CPC, Hendriks SHA, Achterberg S, Oostdijk E, Reidinga AC, Festen-Spanjer B, Brunnekreef GB, Cornet AD, Van den Tempel W, Boelens AD, Koetsier P, Lens JA, Faber HJ, Karakus A, Entjes R, De Jong P, Rettig TCD, Arbous MS, Lalisang RCA, Tonutti M, De Bruin DP, Elbers PWG, Van Bommel J, Reinders MJT. Smit JM, et al. Among authors: de jager cpc. Intell Based Med. 2022;6:100071. doi: 10.1016/j.ibmed.2022.100071. Epub 2022 Aug 6. Intell Based Med. 2022. PMID: 35958674 Free PMC article.
DISCUSSION: We presented a model for dynamic mortality prediction, specifically for critically ill COVID-19 patients, which predicts near-term mortality rather than in-ICU mortality. The potential clinical utility of dynamic mortality models such as benchmarking, improving …
DISCUSSION: We presented a model for dynamic mortality prediction, specifically for critically ill COVID-19 patients, which predicts near- …
Recurrence of IgA nephropathy after kidney transplantation: experience from the Swiss transplant cohort study.
Jäger C, Stampf S, Molyneux K, Barratt J, Golshayan D, Hadaya K, Huynh-Do U, Binet FI, Mueller TF, Koller M, Kim MJ. Jäger C, et al. BMC Nephrol. 2022 May 10;23(1):178. doi: 10.1186/s12882-022-02802-x. BMC Nephrol. 2022. PMID: 35538438 Free PMC article.
BACKGROUND: Recurrence of IgA nephropathy (IgAN) after kidney transplantation occurs in about 30% of patients. The relevance of recurrence for the long-term graft survival is expected to increase, since graft survival continues to improve. ...Younger recipients and women h …
BACKGROUND: Recurrence of IgA nephropathy (IgAN) after kidney transplantation occurs in about 30% of patients. The relevance of recurrence f …
INR and not bilirubin levels predict postoperative morbidity in patients with malignant obstructive jaundice.
Scheufele F, Aichinger L, Jäger C, Demir IE, Schorn S, Demir E, Sargut M, Friess H, Ceyhan GO. Scheufele F, et al. Among authors: jager c. Am J Surg. 2021 Nov;222(5):976-982. doi: 10.1016/j.amjsurg.2021.04.016. Epub 2021 May 12. Am J Surg. 2021. PMID: 34001332
No life-threatening complications (CDIV + V) occurred after long drainage (0.0% vs. 8.9%; p = 0.028) and long-term survival was not compromised. CONCLUSIONS: INR is a suitable predictor for postoperative outcome, while serum-bilirubin levels had no predictive value. ...
No life-threatening complications (CDIV + V) occurred after long drainage (0.0% vs. 8.9%; p = 0.028) and long-term survival was not c …
Patient-reported physical functioning is limited in almost half of critical illness survivors 1-year after ICU-admission: A retrospective single-centre study.
Beumeler LFE, van Wieren A, Buter H, van Zutphen T, Bruins NA, de Jager CM, Koopmans M, Navis GJ, Boerma EC. Beumeler LFE, et al. Among authors: de jager cm. PLoS One. 2020 Dec 14;15(12):e0243981. doi: 10.1371/journal.pone.0243981. eCollection 2020. PLoS One. 2020. PMID: 33315942 Free PMC article.
Characteristics commonly used to predict outcome lack prognostic value when it comes to long-term physical recovery. Therefore, the objective of this study was to assess the incidence of non-recovery in long-stay ICU-patients. ...Commonly used ICU-characteristics, such as …
Characteristics commonly used to predict outcome lack prognostic value when it comes to long-term physical recovery. Therefore, the o …
Spatial patterns of water quality impairments from point source nutrient loads in Germany's largest national River Basin (Weser River).
Yang S, Büttner O, Kumar R, Jäger C, Jawitz JW, Rao PSC, Borchardt D. Yang S, et al. Among authors: jager c. Sci Total Environ. 2019 Dec 20;697:134145. doi: 10.1016/j.scitotenv.2019.134145. Epub 2019 Aug 30. Sci Total Environ. 2019. PMID: 32380617 Free article.
Under Q(R90) conditions [(Q(R50)/Q(R90)) ~ 2.5], water quality impaired locations will likely double for the basin-scale analyses. Long-term water quality data suggested that diffuse sources are the primary contributors for water quality impairments in large streams. ...
Under Q(R90) conditions [(Q(R50)/Q(R90)) ~ 2.5], water quality impaired locations will likely double for the basin-scale analyses. Long-t …
Impact of a Premorbid Psychiatric Disorder on the Incidence of Delirium during ICU Stay, Morbidity, and Long-Term Mortality.
van der Kuur A, Bethlehem C, Bruins N, de Jager C, van Alst C, Haagsma OG, Keijzers A, Boerma EC. van der Kuur A, et al. Among authors: de jager c. Crit Care Res Pract. 2019 Jul 18;2019:6402097. doi: 10.1155/2019/6402097. eCollection 2019. Crit Care Res Pract. 2019. PMID: 31396415 Free PMC article.
A premorbid psychiatric disorder has been associated with an increased incidence of delirium in the general hospital population, but data on the impact of ICU delirium and consequences for morbidity and long-term mortality remain scarce. METHODS: In this single-centre retr …
A premorbid psychiatric disorder has been associated with an increased incidence of delirium in the general hospital population, but data on …
Venous resection during pancreatectomy for pancreatic cancer: a systematic review.
Wang X, Demir IE, Schorn S, Jäger C, Scheufele F, Friess H, Ceyhan GO. Wang X, et al. Among authors: jager c. Transl Gastroenterol Hepatol. 2019 Jun 19;4:46. doi: 10.21037/tgh.2019.06.01. eCollection 2019. Transl Gastroenterol Hepatol. 2019. PMID: 31304423 Free PMC article. Review.
The overall postoperative complications, perioperative mortality, histopathology, and long-term survival were compared between patients undergoing pancreatectomy combined with (VR+ group) or without (VR- group) VR. ...Patients in the VR+ group showed larger tumors and redu …
The overall postoperative complications, perioperative mortality, histopathology, and long-term survival were compared between patien …
Aerosol Mass Spectrometer for Simultaneous Detection of Polyaromatic Hydrocarbons and Inorganic Components from Individual Particles.
Passig J, Schade J, Oster M, Fuchs M, Ehlert S, Jäger C, Sklorz M, Zimmermann R. Passig J, et al. Among authors: jager c. Anal Chem. 2017 Jun 20;89(12):6341-6345. doi: 10.1021/acs.analchem.7b01207. Epub 2017 Jun 9. Anal Chem. 2017. PMID: 28570048
Of particular relevance are polycyclic aromatic hydrocarbons (PAHs) from combustion processes that are associated with both acute and long-term health effects. Usually, online single particle analyses apply laser desorption/ionization (LDI) in a bipolar mass spectrometer, …
Of particular relevance are polycyclic aromatic hydrocarbons (PAHs) from combustion processes that are associated with both acute and long- …
24 results