Roles of FoxM1-driven basal β-cell proliferation in maintenance of β-cell mass and glucose tolerance during adulthood.
Kohata M, Imai J, Izumi T, Yamamoto J, Kawana Y, Endo A, Sugawara H, Seike J, Kubo H, Komamura H, Sato T, Hosaka S, Munakata Y, Asai Y, Kodama S, Takahashi K, Kaneko K, Katagiri H.
Kohata M, et al. Among authors: izumi t.
J Diabetes Investig. 2022 Oct;13(10):1666-1676. doi: 10.1111/jdi.13846. Epub 2022 Jul 15.
J Diabetes Investig. 2022.
PMID: 35633298
Free PMC article.
RESULTS: FoxM1 deficiency suppressed beta-cell proliferation at both ages, indicating critical roles of FoxM1 in basal beta-cell proliferation throughout adulthood. While short-term FoxM1 deficiency affected neither beta-cell mass nor glucose tolerance, long-term Fo …
RESULTS: FoxM1 deficiency suppressed beta-cell proliferation at both ages, indicating critical roles of FoxM1 in basal beta-cell proliferati …