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[A Case of Transverse Colon Cancer in Which Long-Term Chemotherapy Was Performed after Palliative Colonic Stent Placement].
Ueda M, Ikenaga M, Ohta K, Chinen Y, Itakura H, Masui J, Takayama H, Tsuda Y, Nakashima S, Adachi S, Endo S, Yasui M, Noura S, Yamada T. Ueda M, et al. Among authors: itakura h. Gan To Kagaku Ryoho. 2018 Dec;45(13):1892-1894. Gan To Kagaku Ryoho. 2018. PMID: 30692389 Japanese.
We report a case involving a 76-year-old woman with transverse colon cancer undergoing long-term chemotherapy following palliative colonic stent placement. She visited our hospital with a diagnosis of colonic obstruction. ...
We report a case involving a 76-year-old woman with transverse colon cancer undergoing long-term chemotherapy following palliative co …
Heterogeneity of patients receiving artificial nutrition in Japanese psychiatric hospitals: a cross-sectional study.
Hirao A, Abe K, Takayama K, Kondo K, Yokota O, Sato Y, Norikiyo T, Sato S, Nakashima T, Hayashi H, Nakata K, Asaba H, Tanaka K, Tanaka R, Morisada Y, Itakura H, Honda H, Okabe N, Oshima E, Terada S; Middle Western Japan-Dementia Study (mid-Dem study). Hirao A, et al. Among authors: itakura h. Psychogeriatrics. 2016 Nov;16(6):341-348. doi: 10.1111/psyg.12173. Epub 2016 Jan 12. Psychogeriatrics. 2016. PMID: 26756206
More than a few patients with mental disorders, including schizophrenia, also received long-term artificial nutrition. We should pay more attention to chronic dysphasia syndrome in mental disorders....
More than a few patients with mental disorders, including schizophrenia, also received long-term artificial nutrition. We should pay …
The change in low-density lipoprotein cholesterol concentration is positively related to plasma docosahexaenoic acid but not eicosapentaenoic acid.
Itakura H, Yokoyama M, Matsuzaki M, Saito Y, Origasa H, Ishikawa Y, Oikawa S, Sasaki J, Hishida H, Kita T, Kitabatake A, Nakaya N, Sakata T, Shimada K, Shirato K, Matsuzawa Y; JELIS. Itakura H, et al. J Atheroscler Thromb. 2012;19(7):673-9. doi: 10.5551/jat.11593. Epub 2012 May 26. J Atheroscler Thromb. 2012. PMID: 22653220 Free article. Clinical Trial.
AIM: The Japan EPA Lipid Intervention Study (JELIS) reported a 19% reduction of the risk for coronary artery disease after long-term use of pure eicosapentaenoic acid (EPA) in Japanese patients with hypercholesterolemia. ...
AIM: The Japan EPA Lipid Intervention Study (JELIS) reported a 19% reduction of the risk for coronary artery disease after long-term …
Risk factors for cardiovascular events in Japanese patients treated with fluvastatin from the long-term event monitoring (LEM) study.
Morishita R, Itakura H, Nakaya N, Yoshida M, Odawara M, Ichihara A, Mizuno K. Morishita R, et al. Among authors: itakura h. Curr Vasc Pharmacol. 2012 Mar;10(2):178-86. doi: 10.2174/157016112799305049. Curr Vasc Pharmacol. 2012. PMID: 21824105 Clinical Trial.
OBJECTIVE: The long-term event monitoring (LEM) study evaluated the lipid-lowering efficacy and safety of fluvastatin in Japanese patients with hypercholesterolemia. ...After long-term statin treatment, the control of other factors rather than LDL-C alone might be i …
OBJECTIVE: The long-term event monitoring (LEM) study evaluated the lipid-lowering efficacy and safety of fluvastatin in Japanese pat …
Long-term event monitoring study of fluvastatin in Japanese patients with hypercholesterolemia: Efficacy and incidence of cardiac and other events in elderly patients ( 65 years old).
Itakura H, Nakaya N, Kusunoki T, Shimizu N, Hirai S, Mochizuki S, Ishikawa T. Itakura H, et al. J Cardiol. 2011 Jan;57(1):77-88. doi: 10.1016/j.jjcc.2010.09.003. Epub 2010 Nov 9. J Cardiol. 2011. PMID: 21067897 Free article.
OBJECTIVE: This long-term event monitoring (LEM) study was designed to evaluate the long-term lipid-lowering efficacy and safety of fluvastatin (Lochol, Novartis A.G.) along with the incidence of cardiac and other events, and safety of fluvastatin in Japanese patien …
OBJECTIVE: This long-term event monitoring (LEM) study was designed to evaluate the long-term lipid-lowering efficacy and safe …
Long-term safety, tolerability, and antihypertensive efficacy of aliskiren, an oral direct renin inhibitor, in Japanese patients with hypertension.
Kushiro T, Itakura H, Abo Y, Gotou H, Terao S, Keefe DL. Kushiro T, et al. Among authors: itakura h. Hypertens Res. 2009 Mar;32(3):169-75. doi: 10.1038/hr.2008.21. Epub 2009 Jan 23. Hypertens Res. 2009. PMID: 19262478 Clinical Trial.
Aliskiren, the first in a new class of oral direct renin inhibitors, has been shown to reduce blood pressure (BP) in several short-term studies. In this 52-week, open-label, multicenter, parallel-group study, the long-term safety, tolerability, and efficacy of alisk …
Aliskiren, the first in a new class of oral direct renin inhibitors, has been shown to reduce blood pressure (BP) in several short-term …
Relationship between coronary events and serum cholesterol during 10 years of low-dose simvastatin therapy: long-term efficacy and safety in Japanese patients with hypercholesterolemia in the Japan Lipid Intervention Trial (J-LIT) Extension 10 Study, a prospective large-scale observational cohort study.
Itakura H, Kita T, Mabuchi H, Matsuzaki M, Matsuzawa Y, Nakaya N, Oikawa S, Saito Y, Sasaki J, Shimamoto K; J-LIT Study Group. Itakura H, et al. Circ J. 2008 Aug;72(8):1218-24. doi: 10.1253/circj.72.1218. Circ J. 2008. PMID: 18654003 Free article. Clinical Trial.
BACKGROUND: Because many Japanese patients with hypercholesterolemia have received statin therapy for nearly a decade, there was a need to investigate the benefit of long-term treatment. The Japan Lipid Intervention Trial (J-LIT) Extension 10 study was planned to continue …
BACKGROUND: Because many Japanese patients with hypercholesterolemia have received statin therapy for nearly a decade, there was a need to i …
Effects of eicosapentaenoic acid on major coronary events in hypercholesterolaemic patients (JELIS): a randomised open-label, blinded endpoint analysis.
Yokoyama M, Origasa H, Matsuzaki M, Matsuzawa Y, Saito Y, Ishikawa Y, Oikawa S, Sasaki J, Hishida H, Itakura H, Kita T, Kitabatake A, Nakaya N, Sakata T, Shimada K, Shirato K; Japan EPA lipid intervention study (JELIS) Investigators. Yokoyama M, et al. Among authors: itakura h. Lancet. 2007 Mar 31;369(9567):1090-8. doi: 10.1016/S0140-6736(07)60527-3. Lancet. 2007. PMID: 17398308 Clinical Trial.
BACKGROUND: Epidemiological and clinical evidence suggests that an increased intake of long-chain n-3 fatty acids protects against mortality from coronary artery disease. We aimed to test the hypothesis that long-term use of eicosapentaenoic acid (EPA) is effective for pre …
BACKGROUND: Epidemiological and clinical evidence suggests that an increased intake of long-chain n-3 fatty acids protects against mortality …
Sustained reduction of serum cholesterol in low-dose 6-year simvastatin treatment with minimum side effects in 51,321 Japanese hypercholesterolemic patients.
Matsuzawa Y, Kita T, Mabuchi H, Matsuzaki M, Nakaya N, Oikawa S, Saito Y, Sasaki J, Shimamoto K, Itakura H; J-LIT Study Group. Matsuzawa Y, et al. Among authors: itakura h. Circ J. 2003 Apr;67(4):287-94. doi: 10.1253/circj.67.287. Circ J. 2003. PMID: 12655157 Free article.
Hyper-responders, even to low-dose statin, were found for the first time in this large-scale and long-term investigation. Overall adverse drug reactions occurred in 3.3% of subjects during the 6-year treatment, the major events being hepatic and musculoskeletal disorders, …
Hyper-responders, even to low-dose statin, were found for the first time in this large-scale and long-term investigation. Overall adv …
Dietary diacylglycerol suppresses high fat diet-induced hepatic fat accumulation and microsomal triacylglycerol transfer protein activity in rats.
Taguchi H, Omachi T, Nagao T, Matsuo N, Tokimitsu I, Itakura H. Taguchi H, et al. Among authors: itakura h. J Nutr Biochem. 2002 Nov;13(11):678-683. doi: 10.1016/s0955-2863(02)00212-7. J Nutr Biochem. 2002. PMID: 12550065
We have recently shown that the long-term ingestion of dietary diacylglycerol (DAG) mainly containing 1,3-isoform reduces body fat accumulation in humans as compared to triacylglycerol (TAG) with the same fatty acid composition. ...
We have recently shown that the long-term ingestion of dietary diacylglycerol (DAG) mainly containing 1,3-isoform reduces body fat ac …
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