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Long-term health effects perceived by snakebite patients in rural Sri Lanka: A cohort study.
Waiddyanatha S, Silva A, Weerakoon K, Siribaddana S, Isbister GK. Waiddyanatha S, et al. Among authors: isbister gk. PLoS Negl Trop Dis. 2022 Sep 1;16(9):e0010723. doi: 10.1371/journal.pntd.0010723. eCollection 2022 Sep. PLoS Negl Trop Dis. 2022. PMID: 36048902 Free PMC article.
The acute effects of snakebite are often emphasized, with less information on long-term effects. We aimed to describe the long-term health effects perceived by patients followed up after confirmed snakebites. ...Based on two groups of snakebite patients reviewed one …
The acute effects of snakebite are often emphasized, with less information on long-term effects. We aimed to describe the long-ter …
Snakebite Associated Thrombotic Microangiopathy and Recommendations for Clinical Practice.
Noutsos T, Currie BJ, Wijewickrama ES, Isbister GK. Noutsos T, et al. Among authors: isbister gk. Toxins (Basel). 2022 Jan 14;14(1):57. doi: 10.3390/toxins14010057. Toxins (Basel). 2022. PMID: 35051033 Free PMC article. Review.
We propose diagnostic criteria for snakebite-associated TMA as anaemia with >1.0% schistocytes on blood film examination, together with absolute thrombocytopenia (<150 10(9)/L) or a relative decrease in platelet count of >25% from baseline. Patients are at risk of long- …
We propose diagnostic criteria for snakebite-associated TMA as anaemia with >1.0% schistocytes on blood film examination, together with a …
Snakebite-associated thrombotic microangiopathy: an Australian prospective cohort study [ASP30].
Noutsos T, Currie BJ, Isoardi KZ, Brown SGA, Isbister GK. Noutsos T, et al. Among authors: isbister gk. Clin Toxicol (Phila). 2022 Feb;60(2):205-213. doi: 10.1080/15563650.2021.1948559. Epub 2021 Jul 30. Clin Toxicol (Phila). 2022. PMID: 34328386
AKI occurring with snakebite-associated TMA varied in severity, with most achieving DFS, but with a risk of long-term CKD in half. We found no evidence of benefit for TPE in D-AKI....
AKI occurring with snakebite-associated TMA varied in severity, with most achieving DFS, but with a risk of long-term CKD in half. We …
Long-term Effects of Snake Envenoming.
Waiddyanatha S, Silva A, Siribaddana S, Isbister GK. Waiddyanatha S, et al. Among authors: isbister gk. Toxins (Basel). 2019 Mar 31;11(4):193. doi: 10.3390/toxins11040193. Toxins (Basel). 2019. PMID: 30935096 Free PMC article. Review.
Long-term effects of envenoming compromise the quality of life of the survivors of snakebite. ...We classified conditions that last or appear more than six weeks following envenoming as long term or delayed effects of envenoming. Of 257 records identified, 51 articl …
Long-term effects of envenoming compromise the quality of life of the survivors of snakebite. ...We classified conditions that last o …
Neurotoxicity in Russell's viper (Daboia russelii) envenoming in Sri Lanka: a clinical and neurophysiological study.
Silva A, Maduwage K, Sedgwick M, Pilapitiya S, Weerawansa P, Dahanayaka NJ, Buckley NA, Siribaddana S, Isbister GK. Silva A, et al. Among authors: isbister gk. Clin Toxicol (Phila). 2016 Jun;54(5):411-9. doi: 10.3109/15563650.2016.1143556. Epub 2016 Feb 29. Clin Toxicol (Phila). 2016. PMID: 26923566
CONCLUSION: Sri Lankan Russell's viper envenoming causes mild neuromuscular dysfunction with no long-term effects. Indian polyvalent antivenom effectively binds free venom in blood but does not reverse neurotoxicity....
CONCLUSION: Sri Lankan Russell's viper envenoming causes mild neuromuscular dysfunction with no long-term effects. Indian polyvalent …
The pathophysiology of serotonin toxicity in animals and humans: implications for diagnosis and treatment.
Isbister GK, Buckley NA. Isbister GK, et al. Clin Neuropharmacol. 2005 Sep-Oct;28(5):205-14. doi: 10.1097/01.wnf.0000177642.89888.85. Clin Neuropharmacol. 2005. PMID: 16239759 Review.
Severe and life-threatening cases are almost exclusively a result of combinations of antidepressants (usually monoamine oxidase inhibitors and selective serotonin reuptake inhibitors). Unfortunately, the term serotonin syndrome has a number of quite different meanings, and …
Severe and life-threatening cases are almost exclusively a result of combinations of antidepressants (usually monoamine oxidase inhibitors a …
Acute conjunctival inflammation following contact with squashed spider contents.
Isbister GK. Isbister GK. Am J Ophthalmol. 2003 Sep;136(3):563-4. doi: 10.1016/s0002-9394(03)00277-0. Am J Ophthalmol. 2003. PMID: 12967822
CONCLUSIONS: Ocular exposure to the contents of a spider can cause severe pain, swelling, and redness associated with photophobia. The effects are short term, so reassurance, irrigation, and symptomatic treatment are sufficient....
CONCLUSIONS: Ocular exposure to the contents of a spider can cause severe pain, swelling, and redness associated with photophobia. The effec …
Paracetamol overdose in a preterm neonate.
Isbister GK, Bucens IK, Whyte IM. Isbister GK, et al. Arch Dis Child Fetal Neonatal Ed. 2001 Jul;85(1):F70-2. doi: 10.1136/fn.85.1.f70. Arch Dis Child Fetal Neonatal Ed. 2001. PMID: 11420329 Free PMC article. Review.
There was no biochemical evidence of hepatotoxicity, and no long term sequelae. After modelling of the data, the following pharmacokinetic variables were calculated: absorption half life (t(abs)), 0.51 hours; volume of distribution (V/F(oral)), 0.80 litres/kg; clearance (C …
There was no biochemical evidence of hepatotoxicity, and no long term sequelae. After modelling of the data, the following pharmacoki …