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Page 1
Differing effects of oral conjugated equine estrogen and transdermal estradiol on vitamin D metabolism in postmenopausal women: a 4-year longitudinal study.
Santoro AM, Simpson CA, Cong E, Haas A, Sullivan RR, Parziale S, Deng Y, Insogna KL. Santoro AM, et al. Among authors: insogna kl. Menopause. 2022 Oct 1;29(10):1200-1203. doi: 10.1097/GME.0000000000002045. Epub 2022 Aug 20. Menopause. 2022. PMID: 35969885 Clinical Trial.
However, this difference is transient, in that there were no differences at 36 or 48 months. These findings suggest that there may be a short-term benefit to prescribing transdermal estradiol for women who are either vitamin D deficient or vitamin D insufficient....
However, this difference is transient, in that there were no differences at 36 or 48 months. These findings suggest that there may be a shor …
Dietary protein and bone health: a systematic review and meta-analysis from the National Osteoporosis Foundation.
Shams-White MM, Chung M, Du M, Fu Z, Insogna KL, Karlsen MC, LeBoff MS, Shapses SA, Sackey J, Wallace TC, Weaver CM. Shams-White MM, et al. Among authors: insogna kl. Am J Clin Nutr. 2017 Jun;105(6):1528-1543. doi: 10.3945/ajcn.116.145110. Epub 2017 Apr 12. Am J Clin Nutr. 2017. PMID: 28404575 Free article. Review.
Studies were heterogeneous, and confounding could not be excluded. High-quality, long-term studies are needed to clarify dietary protein's role in bone health. ...
Studies were heterogeneous, and confounding could not be excluded. High-quality, long-term studies are needed to clarify dietary prot …
Conventional Therapy in Adults With X-Linked Hypophosphatemia: Effects on Enthesopathy and Dental Disease.
Connor J, Olear EA, Insogna KL, Katz L, Baker S, Kaur R, Simpson CA, Sterpka J, Dubrow R, Zhang JH, Carpenter TO. Connor J, et al. Among authors: insogna kl. J Clin Endocrinol Metab. 2015 Oct;100(10):3625-32. doi: 10.1210/JC.2015-2199. Epub 2015 Jul 15. J Clin Endocrinol Metab. 2015. PMID: 26176801 Free PMC article.
It is unclear whether therapy influences the occurrence of two major long-term morbidities in XLH: enthesopathy and dental disease. OBJECTIVE: The objective of the study was to investigate the relationship between treatment and enthesopathy and dental disease in adult XLH …
It is unclear whether therapy influences the occurrence of two major long-term morbidities in XLH: enthesopathy and dental disease. O …
Increasing dietary protein acutely augments intestinal iron transporter expression and significantly increases iron absorption in rats.
Thomas CE, Gaffney-Stomberg E, Sun BH, O'Brien KO, Kerstetter JE, Insogna KL. Thomas CE, et al. Among authors: insogna kl. FASEB J. 2013 Jun;27(6):2476-83. doi: 10.1096/fj.12-221945. Epub 2013 Feb 27. FASEB J. 2013. PMID: 23447582
Little data are available regarding acute effects of dietary protein on intestinal Fe absorption. The current study evaluated the short-term effects of increasing dietary protein on Fe absorption and expression of genes involved in Fe homeostasis. ...
Little data are available regarding acute effects of dietary protein on intestinal Fe absorption. The current study evaluated the short-t …
Inhibiting gastric acid production does not affect intestinal calcium absorption in young, healthy individuals: a randomized, crossover, controlled clinical trial.
Wright MJ, Sullivan RR, Gaffney-Stomberg E, Caseria DM, O'Brien KO, Proctor DD, Simpson CA, Kerstetter JE, Insogna KL. Wright MJ, et al. Among authors: insogna kl. J Bone Miner Res. 2010 Oct;25(10):2205-11. doi: 10.1002/jbmr.108. J Bone Miner Res. 2010. PMID: 20499372 Free PMC article. Clinical Trial.
Neither calcium absorption (PPI 34.2% +/- 2.4%, placebo 31.5% +/- 2.1%, p = .24) nor urinary calcium (PPI 321 +/- 38 mg/34 hours, placebo 355 +/- 37 mg/34 hours, p = .07) differed between the PPI and placebo groups. It is concluded that short-term gastric acid suppression …
Neither calcium absorption (PPI 34.2% +/- 2.4%, placebo 31.5% +/- 2.1%, p = .24) nor urinary calcium (PPI 321 +/- 38 mg/34 hours, placebo 35 …
The effect of dietary protein on intestinal calcium absorption in rats.
Gaffney-Stomberg E, Sun BH, Cucchi CE, Simpson CA, Gundberg C, Kerstetter JE, Insogna KL. Gaffney-Stomberg E, et al. Among authors: insogna kl. Endocrinology. 2010 Mar;151(3):1071-8. doi: 10.1210/en.2009-0744. Epub 2010 Feb 10. Endocrinology. 2010. PMID: 20147526 Free PMC article.
Isotopic absorption studies have indicated that, at least in the short term, this is primarily due to increased intestinal Ca absorption. ...
Isotopic absorption studies have indicated that, at least in the short term, this is primarily due to increased intestinal Ca absorpt …
Increasing dietary protein requirements in elderly people for optimal muscle and bone health.
Gaffney-Stomberg E, Insogna KL, Rodriguez NR, Kerstetter JE. Gaffney-Stomberg E, et al. Among authors: insogna kl. J Am Geriatr Soc. 2009 Jun;57(6):1073-9. doi: 10.1111/j.1532-5415.2009.02285.x. Epub 2009 Apr 30. J Am Geriatr Soc. 2009. PMID: 19460090
Furthermore, increasing dietary protein increases calcium absorption, which could be anabolic for bone. Available evidence supports a beneficial effect of short-term protein intakes up to 1.6 to 1.8 g/kg per day, although long-term studies are needed to show safety …
Furthermore, increasing dietary protein increases calcium absorption, which could be anabolic for bone. Available evidence supports a benefi …
The effect of proton pump-inhibiting drugs on mineral metabolism.
Insogna KL. Insogna KL. Am J Gastroenterol. 2009 Mar;104 Suppl 2:S2-4. doi: 10.1038/ajg.2009.44. Am J Gastroenterol. 2009. PMID: 19262542 Review.
Two recent studies have reported increased hip fracture rates with long-term proton pump inhibitor (PPI) use raising concerns about adverse effects of this class of drugs on mineral metabolism. One plausible mechanism by which PPIs could affect calcium economy and skeletal …
Two recent studies have reported increased hip fracture rates with long-term proton pump inhibitor (PPI) use raising concerns about a …
The impact of dietary protein on calcium absorption and kinetic measures of bone turnover in women.
Kerstetter JE, O'Brien KO, Caseria DM, Wall DE, Insogna KL. Kerstetter JE, et al. Among authors: insogna kl. J Clin Endocrinol Metab. 2005 Jan;90(1):26-31. doi: 10.1210/jc.2004-0179. Epub 2004 Nov 16. J Clin Endocrinol Metab. 2005. PMID: 15546911
There were no protein-induced effects on net bone balance. These data directly demonstrate that, at least in the short term, high-protein diets are not detrimental to bone....
There were no protein-induced effects on net bone balance. These data directly demonstrate that, at least in the short term, high-pro …
Dietary protein, calcium metabolism, and skeletal homeostasis revisited.
Kerstetter JE, O'Brien KO, Insogna KL. Kerstetter JE, et al. Among authors: insogna kl. Am J Clin Nutr. 2003 Sep;78(3 Suppl):584S-592S. doi: 10.1093/ajcn/78.3.584S. Am J Clin Nutr. 2003. PMID: 12936953 Review.
Recent studies from our laboratory indicate that alterations in dietary protein can, in fact, profoundly affect intestinal calcium absorption. In short-term dietary trials in healthy adults, we fixed calcium intake at 20 mmol/d while dietary protein was increased from 0.7 …
Recent studies from our laboratory indicate that alterations in dietary protein can, in fact, profoundly affect intestinal calcium absorptio …
19 results