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Therapeutic Value of Sentinel Lymph Node Biopsy in Patients With Melanoma: A Randomized Clinical Trial.
Multicenter Selective Lymphadenectomy Trials Study Group; Crystal JS, Thompson JF, Hyngstrom J, Caracò C, Zager JS, Jahkola T, Bowles TL, Pennacchioli E, Beitsch PD, Hoekstra HJ, Moncrieff M, Ingvar C, van Akkooi A, Sabel MS, Levine EA, Agnese D, Henderson M, Dummer R, Neves RI, Rossi CR, Kane JM 3rd, Trocha S, Wright F, Byrd DR, Matter M, Hsueh EC, MacKenzie-Ross A, Kelley M, Terheyden P, Huston TL, Wayne JD, Neuman H, Smithers BM, Ariyan CE, Desai D, Gershenwald JE, Schneebaum S, Gesierich A, Jacobs LK, Lewis JM, McMasters KM, O'Donoghue C, van der Westhuizen A, Sardi A, Barth R, Barone R, McKinnon JG, Slingluff CL, Farma JM, Schultz E, Scheri RP, Vidal-Sicart S, Molina M, Testori AAE, Foshag LJ, Van Kreuningen L, Wang HJ, Sim MS, Scolyer RA, Elashoff DE, Cochran AJ, Faries MB. Multicenter Selective Lymphadenectomy Trials Study Group, et al. Among authors: ingvar c. JAMA Surg. 2022 Sep 1;157(9):835-842. doi: 10.1001/jamasurg.2022.2055. JAMA Surg. 2022. PMID: 35921122 Free PMC article.
OBJECTIVE: To determine how frequently SLN biopsy without completion lymph node dissection (CLND) results in long-term regional nodal disease control in patients with SLN metastases. ...CONCLUSIONS AND RELEVANCE: This randomized clinical trial was the largest prospective e …
OBJECTIVE: To determine how frequently SLN biopsy without completion lymph node dissection (CLND) results in long-term regional nodal …
Long-term outcome of pT1a-b, cN0 breast cancer without axillary dissection or staging: a prospective observational study of 1543 women.
Ingvar C, Ahlgren J, Emdin S, Lofgren L, Nordander M, Niméus E, Arnesson LG. Ingvar C, et al. Br J Surg. 2020 Sep;107(10):1299-1306. doi: 10.1002/bjs.11610. Epub 2020 Apr 26. Br J Surg. 2020. PMID: 32335901
In this era before staging by sentinel node biopsy, routine axillary dissection for staging of early breast cancer was questioned owing to the increased morbidity and lack of perceived benefit. The long-term risk of axillary recurrence when axillary staging is omitted rema …
In this era before staging by sentinel node biopsy, routine axillary dissection for staging of early breast cancer was questioned owing to t …
Survival in 31 670 patients with thin melanomas: a Swedish population-based study.
Isaksson K, Mikiver R, Eriksson H, Lapins J, Nielsen K, Ingvar C, Lyth J. Isaksson K, et al. Among authors: ingvar c. Br J Dermatol. 2021 Jan;184(1):60-67. doi: 10.1111/bjd.19015. Epub 2020 Apr 27. Br J Dermatol. 2021. PMID: 32133615 Free article.
Although we could show a decreased MSS for patients with 0.7 mm thickness and above, the long-term survival and, in addition, a very favourable CMSS for those patients do not support more extended follow-up programmes than the current recommendations in Sweden....
Although we could show a decreased MSS for patients with 0.7 mm thickness and above, the long-term survival and, in addition, a very …
Tertiary lymphoid structures improve immunotherapy and survival in melanoma.
Cabrita R, Lauss M, Sanna A, Donia M, Skaarup Larsen M, Mitra S, Johansson I, Phung B, Harbst K, Vallon-Christersson J, van Schoiack A, Lövgren K, Warren S, Jirström K, Olsson H, Pietras K, Ingvar C, Isaksson K, Schadendorf D, Schmidt H, Bastholt L, Carneiro A, Wargo JA, Svane IM, Jönsson G. Cabrita R, et al. Among authors: ingvar c. Nature. 2020 Jan;577(7791):561-565. doi: 10.1038/s41586-019-1914-8. Epub 2020 Jan 15. Nature. 2020. PMID: 31942071
Checkpoint blockade therapies that reactivate tumour-associated T cells can induce durable tumour control and result in the long-term survival of patients with advanced cancers(1). Current predictive biomarkers for therapy response include high levels of intratumour immuno …
Checkpoint blockade therapies that reactivate tumour-associated T cells can induce durable tumour control and result in the long-term …
Correlation of histopathologic characteristics to protein expression and function in malignant melanoma.
Welinder C, Pawłowski K, Szasz AM, Yakovleva M, Sugihara Y, Malm J, Jönsson G, Ingvar C, Lundgren L, Baldetorp B, Olsson H, Rezeli M, Laurell T, Wieslander E, Marko-Varga G. Welinder C, et al. Among authors: ingvar c. PLoS One. 2017 Apr 26;12(4):e0176167. doi: 10.1371/journal.pone.0176167. eCollection 2017. PLoS One. 2017. PMID: 28445515 Free PMC article.
However, such analysis is hampered by the complexity of the disease, heterogeneity of patients, tumors, and samples themselves. With the long term aim of quest for better diagnostics biomarkers, as well as predictive and prognostic markers, we focused on relating high reso …
However, such analysis is hampered by the complexity of the disease, heterogeneity of patients, tumors, and samples themselves. With the lon …
Long-term Follow-up After Interstitial Laser Thermotherapy of Breast Cancer.
Haraldsdóttir KH, Ingvar C, Stenram U, Tranberg KG. Haraldsdóttir KH, et al. Among authors: ingvar c. Anticancer Res. 2015 Nov;35(11):6147-52. Anticancer Res. 2015. PMID: 26504041
AIM: To review the effect of immunological changes induced by interstitial laser thermotherapy (ILT) on long-term outcome of patients with breast cancer. PATIENTS AND METHODS: Twenty-four patients with invasive breast cancer were treated with ILT followed by standard surgi …
AIM: To review the effect of immunological changes induced by interstitial laser thermotherapy (ILT) on long-term outcome of patients …
Serial monitoring of circulating tumor DNA in patients with primary breast cancer for detection of occult metastatic disease.
Olsson E, Winter C, George A, Chen Y, Howlin J, Tang MH, Dahlgren M, Schulz R, Grabau D, van Westen D, Fernö M, Ingvar C, Rose C, Bendahl PO, Rydén L, Borg Å, Gruvberger-Saal SK, Jernström H, Saal LH. Olsson E, et al. Among authors: ingvar c. EMBO Mol Med. 2015 Aug;7(8):1034-47. doi: 10.15252/emmm.201404913. EMBO Mol Med. 2015. PMID: 25987569 Free PMC article.
Using an approach combining low-coverage whole-genome sequencing of primary tumors and quantification of tumor-specific rearrangements in plasma by droplet digital PCR, we identify for the first time that ctDNA monitoring is highly accurate for postsurgical discrimination between …
Using an approach combining low-coverage whole-genome sequencing of primary tumors and quantification of tumor-specific rearrangements in pl …
Invasive lobular carcinoma of the breast: long-term prognostic value of Ki67 and histological grade, alone and in combination with estrogen receptor.
Narbe U, Bendahl PO, Grabau D, Rydén L, Ingvar C, Fernö M. Narbe U, et al. Among authors: ingvar c. Springerplus. 2014 Feb 6;3:70. doi: 10.1186/2193-1801-3-70. eCollection 2014. Springerplus. 2014. PMID: 24567879 Free PMC article.
BACKGROUND: The aim of the present study was to investigate the long-term impact of prognostic factors in invasive lobular carcinoma (ILC) of the breast, with a primary focus on Ki67 and histological grade, alone and in combination with estrogen receptor (ER). ...CONCLUSIO …
BACKGROUND: The aim of the present study was to investigate the long-term impact of prognostic factors in invasive lobular carcinoma …
Prognostic subclassifications of T1 cutaneous melanomas based on ulceration, tumour thickness and Clark's level of invasion: results of a population-based study from the Swedish Melanoma Register.
Lyth J, Hansson J, Ingvar C, Månsson-Brahme E, Naredi P, Stierner U, Wagenius G, Lindholm C; Swedish Melanoma Study Group. Lyth J, et al. Among authors: ingvar c. Br J Dermatol. 2013 Apr;168(4):779-86. doi: 10.1111/bjd.12095. Epub 2013 Jan 18. Br J Dermatol. 2013. PMID: 23066913 Free article.
RESULTS: Ulceration, tumour thickness and Clark's level of invasion all showed significant, independent, long-term prognostic information. By combining these factors the patients could be subdivided into three risk groups: a low-risk group (67.9% of T1 cases) with a 10-yea …
RESULTS: Ulceration, tumour thickness and Clark's level of invasion all showed significant, independent, long-term prognostic informa …
23 results