Search Page
Save citations to file
Email citations
Send citations to clipboard
Add to Collections
Add to My Bibliography
Create a file for external citation management software
Your saved search
Your RSS Feed
Search Results
3 results
Filters applied: . Clear all
Page 1
A Cell-based beta-Lactamase Reporter Gene Assay for the CREB Signaling Pathway.
Curr Chem Genomics. 2009 Jan 1;3(1):7-12. doi: 10.2174/1875397300903010007.
Curr Chem Genomics. 2009.
PMID: 19936037
Free PMC article.
CREB-mediated transcription has been implicated in a wide variety of important physiological processes, including long-term memory, and enhancement of CREB signaling has been suggested as an attractive therapeutic strategy for human memory disorders. ...
CREB-mediated transcription has been implicated in a wide variety of important physiological processes, including long-term memory, a …
Identification of compounds that potentiate CREB signaling as possible enhancers of long-term memory.
Xia M, Huang R, Guo V, Southall N, Cho MH, Inglese J, Austin CP, Nirenberg M.
Xia M, et al. Among authors: inglese j.
Proc Natl Acad Sci U S A. 2009 Feb 17;106(7):2412-7. doi: 10.1073/pnas.0813020106. Epub 2009 Feb 5.
Proc Natl Acad Sci U S A. 2009.
PMID: 19196967
Free PMC article.
Many studies have implicated the cAMP Response Element Binding (CREB) protein signaling pathway in long-term memory. To identify small molecule enhancers of CREB activation of gene expression, we screened approximately 73,000 compounds, each at 7-15 concentrations in a qua …
Many studies have implicated the cAMP Response Element Binding (CREB) protein signaling pathway in long-term memory. To identify smal …
Item in Clipboard
gamma-Fluoromethotrexate: synthesis and biological activity of a potent inhibitor of dihydrofolate reductase with greatly diminished ability to form poly-gamma-glutamates.
Galivan J, Inglese J, McGuire JJ, Nimec Z, Coward JK.
Galivan J, et al. Among authors: inglese j.
Proc Natl Acad Sci U S A. 1985 May;82(9):2598-602. doi: 10.1073/pnas.82.9.2598.
Proc Natl Acad Sci U S A. 1985.
PMID: 2581252
Free PMC article.
The data strongly suggest that prolonged toxicity of MTX is a result of metabolic conversion to MTX polyglutamates and that these effects are far more dramatic in short-term than in long-term exposure to the antifolates....
The data strongly suggest that prolonged toxicity of MTX is a result of metabolic conversion to MTX polyglutamates and that these effects ar …
Item in Clipboard
Cite
Cite