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Exposure to high environmental temperature in the sauna does not change plasma indocyanine green (ICG) clearance in healthy subjects.
Vanakoski J, Idänpään-Heikkilä JJ, Seppälä T. Vanakoski J, et al. Among authors: idanpaan heikkila jj. Pharmacol Toxicol. 1996 Feb;78(2):94-8. doi: 10.1111/j.1600-0773.1996.tb00187.x. Pharmacol Toxicol. 1996. PMID: 8822042 Clinical Trial.
No statistically significant differences in the CI, t1/2 beta or Vss of ICG were detected between the control and sauna bathing sessions. The results suggest that short-term exposure to high ambient temperatures during sauna bathing does not affect hepatic blood flow. Cons …
No statistically significant differences in the CI, t1/2 beta or Vss of ICG were detected between the control and sauna bathing sessions. Th …
Effects of heat exposure in a Finnish sauna on the pharmacokinetics and metabolism of midazolam.
Vanakoski J, Idänpään-Heikkilä JJ, Olkkola KT, Seppälä T. Vanakoski J, et al. Among authors: idanpaan heikkila jj. Eur J Clin Pharmacol. 1996;51(3-4):335-8. doi: 10.1007/s002280050208. Eur J Clin Pharmacol. 1996. PMID: 9010709 Clinical Trial.
OBJECTIVE: The effect of short-term heat exposure in a Finnish sauna on hepatic first-pass metabolism and the capacity to metabolize midazolam were studied in a crossover trial. ...The pharmacokinetics of intravenous midazolam were not affected by sauna bathing. CONCLUSION …
OBJECTIVE: The effect of short-term heat exposure in a Finnish sauna on hepatic first-pass metabolism and the capacity to metabolize …