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Diagnosed and subjectively perceived long-term effects of COVID-19 infection on olfactory function assessed by supervised machine learning.
Lötsch J, Brosig O, Slobodova J, Kringel D, Haehner A, Hummel T. Lötsch J, et al. Among authors: hummel t. Chem Senses. 2024 Jan 1;49:bjad051. doi: 10.1093/chemse/bjad051. Chem Senses. 2024. PMID: 38213039
The time that has elapsed since the emergence of COVID-19 now allows for assessing the long-term prognosis of its olfactory impact. Participants (n = 722) of whom n = 464 reported having had COVID-19 dating back with a mode of 174 days were approached in a museum as a rela …
The time that has elapsed since the emergence of COVID-19 now allows for assessing the long-term prognosis of its olfactory impact. P …
Trigeminal function in patients with COVID-associated olfactory loss.
Juratli JH, Garefis K, Konstantinidis I, Hummel T. Juratli JH, et al. Among authors: hummel t. Eur Arch Otorhinolaryngol. 2024 May;281(5):2403-2411. doi: 10.1007/s00405-023-08391-1. Epub 2023 Dec 21. Eur Arch Otorhinolaryngol. 2024. PMID: 38127097
PURPOSE: Olfactory dysfunction (OD) can be a long-term consequence of various viral infections, including COVID-19. ...
PURPOSE: Olfactory dysfunction (OD) can be a long-term consequence of various viral infections, including COVID-19. ...
Patients with olfactory loss exhibit pronounced adaptation to chemosensory stimuli: an electrophysiological study.
Li Z, Salloum R, Hummel T. Li Z, et al. Among authors: hummel t. Rhinology. 2023 Oct 1;61(5):449-455. doi: 10.4193/Rhin23.049. Rhinology. 2023. PMID: 37334730
Patients with olfactory loss exhibited pronounced olfactory and trigeminal adaptation within the long-term design, without such effects in healthy controls. Odor sensitivity correlated with both olfactory and trigeminal amplitude changes: the worse the olfactory sensitivit …
Patients with olfactory loss exhibited pronounced olfactory and trigeminal adaptation within the long-term design, without such effec …
Effect of postoperative systemic prednisolone on short-term and long-term outcomes in chronic rhinosinusitis with nasal polyps: A multi-centered randomized clinical trial.
Mueller SK, Wendler O, Mayr S, Traxdorf M, Hosemann W, Olze H, Steinhart H, Wiegand S, Teymoortash A, Kuehnel T, Hackenberg S, Hummel T, Ambrosch P, Fazel A, Schick B, Baenkler HW, Koch M, Buerner H, Mantsopoulos K, Grundtner P, Nocera A, Agaimy A, Bleier B, Iro H. Mueller SK, et al. Among authors: hummel t. Front Immunol. 2023 Mar 8;14:1075066. doi: 10.3389/fimmu.2023.1075066. eCollection 2023. Front Immunol. 2023. PMID: 36969262 Free PMC article. Clinical Trial.
CONCLUSION: In conclusion, the addition of postoperative systemic steroids after primary FESS did not confer a benefit over topical steroid nasal spray alone with respect to NPS, SNQOL, LKS, GQOL, sinonasal symptoms, smell scores, recurrence rates, the need for revision surgery o …
CONCLUSION: In conclusion, the addition of postoperative systemic steroids after primary FESS did not confer a benefit over topical steroid …
Development and validation of the Olfactory Memory Test Battery (OMTB) based on odors with high- and low-verbalizability.
Li SB, Yan C, Hummel T, Zou LQ. Li SB, et al. Among authors: hummel t. J Neurosci Methods. 2023 Mar 15;388:109826. doi: 10.1016/j.jneumeth.2023.109826. Epub 2023 Feb 22. J Neurosci Methods. 2023. PMID: 36822275
The test contained two odor categories (high- and low-verbalizability odors), each consisting of three subtests (short- and long-term memory and working memory). RESULTS: Satisfactory test-retest reliability and solid validity of the odor recognition and working memory tes …
The test contained two odor categories (high- and low-verbalizability odors), each consisting of three subtests (short- and long-term …
Real-world-effectiveness of biological treatment for severe chronic rhinosinusitis with nasal polyps.
Haxel BR, Hummel T, Fruth K, Lorenz K, Gunder N, Nahrath P, Cuevas M. Haxel BR, et al. Among authors: hummel t. Rhinology. 2022 Dec 1;60(6):435-443. doi: 10.4193/Rhin22.129. Rhinology. 2022. PMID: 36150163 Clinical Trial.
METHODS: This per protocol analysis included patients with an indication for biological treatment because of uncontrolled CRSwNP, despite long-term nasal steroid treatment, systemic steroid use and/ or endonasal sinus surgery. ...
METHODS: This per protocol analysis included patients with an indication for biological treatment because of uncontrolled CRSwNP, despite lo …
Safety of Thioguanine in Pediatric Inflammatory Bowel Disease: A Multi-Center Case Series.
Bayoumy AB, Jagt JZ, van Wering HM, de Ridder L, Hummel T, Wolters VM, Stapelbroek J, Benninga MA, Mulder CJJ, de Boer NKH, de Meij TGJ; Kids with Crohn’s, Colitis (KiCC) Working Group for Collaborative Paediatric IBD Research in the Netherlands. Bayoumy AB, et al. Among authors: hummel t. J Pediatr Gastroenterol Nutr. 2022 Dec 1;75(6):e111-e115. doi: 10.1097/MPG.0000000000003621. Epub 2022 Sep 20. J Pediatr Gastroenterol Nutr. 2022. PMID: 36136124 Free PMC article.
CONCLUSIONS: In pediatric IBD, TG seems a safe alternative in case of AZA-induced pancreatitis. Further research assessing long-term TG-related safety and efficacy is needed....
CONCLUSIONS: In pediatric IBD, TG seems a safe alternative in case of AZA-induced pancreatitis. Further research assessing long-term …
Training with Odors Impacts Hippocampal Thickness in Patients with Mild Cognitive Impairment.
Haehner A, Chen B, Espin M, Haussmann R, Matthes C, Desser D, Loessner L, Brandt MD, Donix M, Hummel T. Haehner A, et al. Among authors: hummel t. J Alzheimers Dis. 2022;88(2):743-755. doi: 10.3233/JAD-220248. J Alzheimers Dis. 2022. PMID: 35694924 Clinical Trial.
OBJECTIVE: The aim of this randomized, prospective, controlled, blinded study was to assess whether a 4-month period of olfactory training (frequent short-term sniffing various odors) may have an effect on olfactory function, cognitive function, and morphology of medial te …
OBJECTIVE: The aim of this randomized, prospective, controlled, blinded study was to assess whether a 4-month period of olfactory training ( …
Safety, Pharmacodynamics, and Pharmacokinetics of P2X3 Receptor Antagonist Eliapixant (BAY 1817080) in Healthy Subjects: Double-Blind Randomized Study.
Friedrich C, Francke K, Gashaw I, Scheerans C, Klein S, Fels L, Smith JA, Hummel T, Morice A. Friedrich C, et al. Among authors: hummel t. Clin Pharmacokinet. 2022 Aug;61(8):1143-1156. doi: 10.1007/s40262-022-01126-1. Epub 2022 May 28. Clin Pharmacokinet. 2022. PMID: 35624408 Free PMC article. Clinical Trial.
CLINICAL TRIAL REGISTRATION: Clinicaltrials.gov: NCT03310645 (initial registration: 16 October, 2017). There are few effective treatments for patients with a long-term (chronic) cough. It is thought that chronic cough is caused by nerves becoming oversensitive, wrongly cau …
CLINICAL TRIAL REGISTRATION: Clinicaltrials.gov: NCT03310645 (initial registration: 16 October, 2017). There are few effective treatments fo …
The nasal cycle before and after nasal septoplasty.
Letzel J, Darbinjan A, Hummel T. Letzel J, et al. Among authors: hummel t. Eur Arch Otorhinolaryngol. 2022 Oct;279(10):4961-4968. doi: 10.1007/s00405-022-07322-w. Epub 2022 Mar 14. Eur Arch Otorhinolaryngol. 2022. PMID: 35286439
Testing included multiple questionnaires regarding nasal breathing and olfactory function, anterior rhinoscopy, rhinomanometry, acoustic rhinometry, and long-term rhinoflowmetry over 24 h. RESULTS: Nasal septoplasty was associated with subjectively improved nasal breathing …
Testing included multiple questionnaires regarding nasal breathing and olfactory function, anterior rhinoscopy, rhinomanometry, acoustic rhi …
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