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Disrupted BMP-9 Signaling Impairs Pulmonary Vascular Integrity in Hepatopulmonary Syndrome.
Robert F, Certain MC, Baron A, Thuillet R, Duhaut L, Ottaviani M, Kamel Chelgham M, Normand C, Berrebeh N, Ricard N, Furlan V, Desroches-Castan A, Gonzales E, Jacquemin E, Sitbon O, Humbert M, Bailly S, Coilly A, Guignabert C, Tu L, Savale L. Robert F, et al. Among authors: humbert m. Am J Respir Crit Care Med. 2024 Apr 16. doi: 10.1164/rccm.202307-1289OC. Online ahead of print. Am J Respir Crit Care Med. 2024. PMID: 38626313
Two animal models of portal hypertension were employed: common bile duct ligation (CBDL) with cirrhosis and long-term partial portal vein ligation (PPVL) without cirrhosis. Additionally, the therapeutic effect of low-dose BMP activator FK506 was investigated, and the pulmo …
Two animal models of portal hypertension were employed: common bile duct ligation (CBDL) with cirrhosis and long-term partial portal …
High-resolution CT phenotypes in pulmonary sarcoidosis: a multinational Delphi consensus study.
Desai SR, Sivarasan N, Johannson KA, George PM, Culver DA, Devaraj A, Lynch DA, Milne D, Renzoni E, Nunes H, Sverzellati N, Spagnolo P, Baughman RP, Yadav R, Piciucchi S, Walsh SLF, Kouranos V, Wells AU; Sarcoid Delphi Group. Desai SR, et al. Lancet Respir Med. 2024 May;12(5):409-418. doi: 10.1016/S2213-2600(23)00267-9. Epub 2023 Dec 14. Lancet Respir Med. 2024. PMID: 38104579 Review.
One view of sarcoidosis is that the term covers many different diseases. However, no classification framework exists for the future exploration of pathogenetic pathways, genetic or trigger predilections, patterns of lung function impairment, or treatment separations, or fo …
One view of sarcoidosis is that the term covers many different diseases. However, no classification framework exists for the future e …
Thirty years of surgical management of pediatric pulmonary hypertension: Mid-term outcomes following reverse Potts shunt and transplantation.
Valdeolmillos E, Le Pavec J, Audié M, Savale L, Jais X, Montani D, Sitbon O, Feuillet S, Mercier O, Petit J, Humbert M, Fadel E, Belli E, Hascoët S. Valdeolmillos E, et al. Among authors: humbert m. J Thorac Cardiovasc Surg. 2023 Dec 3:S0022-5223(23)01121-2. doi: 10.1016/j.jtcvs.2023.11.045. Online ahead of print. J Thorac Cardiovasc Surg. 2023. PMID: 38052251
METHODS: This single-center retrospective cohort study included 61 consecutive pediatric patients with PAH managed by RPS (2004-2020) or transplantation (1988-2020). Their mid-term outcomes were assessed. RESULTS: Compared with the 20 patients managed by RPS, the 41 transp …
METHODS: This single-center retrospective cohort study included 61 consecutive pediatric patients with PAH managed by RPS (2004-2020) or tra …
Impact of exacerbation history on long-term efficacy of dupilumab in patients with asthma.
Corren J, Katelaris CH, Castro M, Maspero JF, Humbert M, Halpin DMG, Altincatal A, Pandit-Abid N, Soler X, Radwan A, Jacob-Nara JA, Deniz Y, Rowe PJ. Corren J, et al. Among authors: humbert m. ERJ Open Res. 2023 Oct 16;9(5):00037-2023. doi: 10.1183/23120541.00037-2023. eCollection 2023 Sep. ERJ Open Res. 2023. PMID: 37859672 Free PMC article.
Overall, safety was consistent with the known dupilumab safety profile. This post hoc analysis assessed long-term dupilumab efficacy for up to 3 years by exacerbation history. ...CONCLUSION: For patients with uncontrolled, moderate-to-severe asthma with elevation of at lea …
Overall, safety was consistent with the known dupilumab safety profile. This post hoc analysis assessed long-term dupilumab efficacy …
Parents, Teachers, and Community: A Team Approach to Developing Physical Competence in Children.
Chapelski MS, Erlandson MC, Stoddart AL, Froehlich Chow A, Baxter-Jones ADG, Humbert ML. Chapelski MS, et al. Among authors: humbert ml. Children (Basel). 2023 Aug 9;10(8):1364. doi: 10.3390/children10081364. Children (Basel). 2023. PMID: 37628363 Free PMC article.
Increasing children's physical activity engagement has short- and long-term health benefits. Developing physical competence is a key component of children's engagement in physical activity. ...
Increasing children's physical activity engagement has short- and long-term health benefits. Developing physical competence is a key …
Clinical features and long-term outcomes of patients with systemic polyarteritis nodosa diagnosed since 2005: Data from 196 patients.
Rohmer J, Nguyen Y, Trefond L, Agard C, Allain JS, Berezne A, Charles P, Cohen P, Gondran G, Groh M, Huscenot T, Lacout C, Lazaro E, London J, Maurier F, Mekinian A, Mesbah R, Nubourgh I, Perard L, Puéchal X, Pugnet G, Puyade M, Queyrel V, Roux A, Rouzaud D, Durel CA, Guillevin L, Terrier B; French Vasculitis Study Group (FVSG). Rohmer J, et al. J Autoimmun. 2023 Sep;139:103093. doi: 10.1016/j.jaut.2023.103093. Epub 2023 Aug 1. J Autoimmun. 2023. PMID: 37536165
Long-Term Effects of Sotatercept on Right Ventricular Function: Results From the PULSAR Study.
Gomberg-Maitland M, McLaughlin VV, Badesch DB, Ghofrani HA, Hoeper MM, Humbert M, Preston IR, Souza R, Waxman AB, de Oliveira Pena J, Lu JT, Manimaran S, Gibbs JSR. Gomberg-Maitland M, et al. Among authors: humbert m. JACC Heart Fail. 2023 Oct;11(10):1457-1459. doi: 10.1016/j.jchf.2023.05.030. Epub 2023 Jul 12. JACC Heart Fail. 2023. PMID: 37452806 No abstract available.
Management of Acutely Decompensated Pulmonary Hypertension.
Savale L, Kularatne M, Roche A, Pichon J, Baron A, Boucly A, Sitbon O, Humbert M. Savale L, et al. Among authors: humbert m. Semin Respir Crit Care Med. 2023 Dec;44(6):762-770. doi: 10.1055/s-0043-1770119. Epub 2023 Jun 27. Semin Respir Crit Care Med. 2023. PMID: 37369216
These patients should be managed at expert centers in an intensive care setting with a multidisciplinary team of practitioners experienced in the management of right heart dysfunction given the high short- and long-term mortality resulting from acute decompensated right he …
These patients should be managed at expert centers in an intensive care setting with a multidisciplinary team of practitioners experienced i …
[Post-COVID-19 syndrome].
Montani D, Savale L, Noel N, Meyrignac O, Colle R, Gasnier M, Corruble E, Beurnier A, Jutant EM, Pham T, Lecoq AL, Papon JF, Figuereido S, Harrois A, Humbert M, Monnet X; pour le Groupe d’étude Comebac. Montani D, et al. Among authors: humbert m. Bull Acad Natl Med. 2023 Jun;207(6):812-820. doi: 10.1016/j.banm.2023.01.029. Epub 2023 Apr 25. Bull Acad Natl Med. 2023. PMID: 37292432 Free PMC article. Review. French.
Vaccination, on the other hand, seems to reduce their incidence. The sheer number of affected patients makes long-term COVID-19 syndrome a public health challenge....
Vaccination, on the other hand, seems to reduce their incidence. The sheer number of affected patients makes long-term COVID-19 syndr …
2022 Update of indications and contraindications for lung transplantation in France.
Le Pavec J, Pison C, Hirschi S, Bunel V, Mordant P, Brugière O, Guen ML, Olland A, Coiffard B, Renaud-Picard B, Tissot A, Brioude G, Borie R, Crestani B, Deslée G, Stelianides S, Mal H, Schuller A, Falque L, Lorillon G, Tazi A, Burgel PR, Grenet D, De Miranda S, Bergeron A, Launay D, Cottin V, Nunes H, Valeyre D, Uzunhan Y, Prévot G, Sitbon O, Montani D, Savale L, Humbert M, Fadel E, Mercier O, Mornex JF, Dauriat G, Reynaud-Gaubert M. Le Pavec J, et al. Among authors: humbert m. Respir Med Res. 2023 Jun;83:100981. doi: 10.1016/j.resmer.2022.100981. Epub 2022 Nov 28. Respir Med Res. 2023. PMID: 36565563
The considerable developments have been driven over the years by indefatigable work conducted at LTx centers to improve donor and recipient selection, combined with multifaceted efforts to overcome challenges raised by the surgical procedure, perioperative care, and long-term …
The considerable developments have been driven over the years by indefatigable work conducted at LTx centers to improve donor and recipient …
162 results