Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My NCBI Filters

Text availability

Article attribute

Article type

Publication date

Search Results

14 results

Filters applied: . Clear all
Page 1
Sprint and Strength Training Modulates Autophagy and Proteostasis in Aging Sprinters.
Hentilä J, Hulmi JJ, Laakkonen EK, Ahtiainen JP, Suominen H, Korhonen MT. Hentilä J, et al. Among authors: hulmi jj. Med Sci Sports Exerc. 2020 Sep;52(9):1948-1959. doi: 10.1249/MSS.0000000000002340. Med Sci Sports Exerc. 2020. PMID: 32205677 Clinical Trial.
PURPOSE: Exercise and aging may modulate muscle protein homeostasis and autophagy, but few studies examine highly trained middle-age or older individuals. This study elucidated the effects of a new long-term training stimulus on markers of muscle autophagy and unfolded pro …
PURPOSE: Exercise and aging may modulate muscle protein homeostasis and autophagy, but few studies examine highly trained middle-age or olde …
Substantial fat mass loss reduces low-grade inflammation and induces positive alteration in cardiometabolic factors in normal-weight individuals.
Sarin HV, Lee JH, Jauhiainen M, Joensuu A, Borodulin K, Männistö S, Jin Z, Terwilliger JD, Isola V, Ahtiainen JP, Häkkinen K, Kristiansson K, Hulmi JJ, Perola M. Sarin HV, et al. Among authors: hulmi jj. Sci Rep. 2019 Mar 5;9(1):3450. doi: 10.1038/s41598-019-40107-6. Sci Rep. 2019. PMID: 30837600 Free PMC article.
The accumulation of fat, especially in visceral sites, is a significant risk factor for several chronic diseases with altered cardiometabolic homeostasis. We studied how intensive long-term weight loss and subsequent weight regain affect physiological changes, by longitudi …
The accumulation of fat, especially in visceral sites, is a significant risk factor for several chronic diseases with altered cardiometaboli …
VEGF-B gene therapy inhibits doxorubicin-induced cardiotoxicity by endothelial protection.
Räsänen M, Degerman J, Nissinen TA, Miinalainen I, Kerkelä R, Siltanen A, Backman JT, Mervaala E, Hulmi JJ, Kivelä R, Alitalo K. Räsänen M, et al. Among authors: hulmi jj. Proc Natl Acad Sci U S A. 2016 Nov 15;113(46):13144-13149. doi: 10.1073/pnas.1616168113. Epub 2016 Oct 31. Proc Natl Acad Sci U S A. 2016. PMID: 27799559 Free PMC article.
Congestive heart failure is one of the leading causes of disability in long-term survivors of cancer. The anthracycline antibiotic doxorubicin (DOX) is used to treat a variety of cancers, but its utility is limited by its cumulative cardiotoxicity. ...
Congestive heart failure is one of the leading causes of disability in long-term survivors of cancer. The anthracycline antibiotic do …
The effects of whey protein with or without carbohydrates on resistance training adaptations.
Hulmi JJ, Laakso M, Mero AA, Häkkinen K, Ahtiainen JP, Peltonen H. Hulmi JJ, et al. J Int Soc Sports Nutr. 2015 Dec 16;12:48. doi: 10.1186/s12970-015-0109-4. eCollection 2015. J Int Soc Sports Nutr. 2015. PMID: 26677350 Free PMC article. Clinical Trial.
However, the individual and combined effects of whey protein and carbohydrates on long-term resistance training adaptations are poorly understood. METHODS: A four-week preparatory RT period was conducted in previously untrained males to standardize the training background …
However, the individual and combined effects of whey protein and carbohydrates on long-term resistance training adaptations are poorl …
Vitamin C and E supplementation alters protein signalling after a strength training session, but not muscle growth during 10 weeks of training.
Paulsen G, Hamarsland H, Cumming KT, Johansen RE, Hulmi JJ, Børsheim E, Wiig H, Garthe I, Raastad T. Paulsen G, et al. Among authors: hulmi jj. J Physiol. 2014 Dec 15;592(24):5391-408. doi: 10.1113/jphysiol.2014.279950. Epub 2014 Nov 10. J Physiol. 2014. PMID: 25384788 Free PMC article.
We concluded that vitamin C and E supplementation interfered with the acute cellular response to heavy-load resistance exercise and demonstrated tentative long-term negative effects on adaptation to strength training....
We concluded that vitamin C and E supplementation interfered with the acute cellular response to heavy-load resistance exercise and demonstr …
Are skeletal muscle FNDC5 gene expression and irisin release regulated by exercise and related to health?
Pekkala S, Wiklund PK, Hulmi JJ, Ahtiainen JP, Horttanainen M, Pöllänen E, Mäkelä KA, Kainulainen H, Häkkinen K, Nyman K, Alén M, Herzig KH, Cheng S. Pekkala S, et al. Among authors: hulmi jj. J Physiol. 2013 Nov 1;591(21):5393-400. doi: 10.1113/jphysiol.2013.263707. Epub 2013 Sep 2. J Physiol. 2013. PMID: 24000180 Free PMC article.
The male subjects in the study performed single exercises: (1) 1 h low-intensity aerobic exercise (AE) (middle-aged, n = 17), (2) a heavy-intensity resistance exercise (RE) bout (young n = 10, older n = 11) (27 vs. 62 years), (3) long-term 21 weeks endurance exercise (EE) …
The male subjects in the study performed single exercises: (1) 1 h low-intensity aerobic exercise (AE) (middle-aged, n = 17), (2) a heavy-in …
Variable resistance training promotes greater fatigue resistance but not hypertrophy versus constant resistance training.
Walker S, Hulmi JJ, Wernbom M, Nyman K, Kraemer WJ, Ahtiainen JP, Häkkinen K. Walker S, et al. Among authors: hulmi jj. Eur J Appl Physiol. 2013 Sep;113(9):2233-44. doi: 10.1007/s00421-013-2653-4. Epub 2013 May 1. Eur J Appl Physiol. 2013. PMID: 23636698
This may indicate a greater potential for adaptation during long-term training. Twelve (constant resistance group) and 11 (variable resistance group) men completed 20 weeks of resistance training with 10 men as non-training controls. ...
This may indicate a greater potential for adaptation during long-term training. Twelve (constant resistance group) and 11 (variable r …
Muscle protein synthesis, mTORC1/MAPK/Hippo signaling, and capillary density are altered by blocking of myostatin and activins.
Hulmi JJ, Oliveira BM, Silvennoinen M, Hoogaars WM, Ma H, Pierre P, Pasternack A, Kainulainen H, Ritvos O. Hulmi JJ, et al. Am J Physiol Endocrinol Metab. 2013 Jan 1;304(1):E41-50. doi: 10.1152/ajpendo.00389.2012. Epub 2012 Oct 31. Am J Physiol Endocrinol Metab. 2013. PMID: 23115080 Free article.
The phosphorylation of YAP (Yes-associated protein), a readout of activated Hippo signaling, increased after short- and longer-term myostatin and activin blocking and in exercised muscle. Moreover, dystrophic mdx mice had elevated phosphorylated and especially total YAP pr …
The phosphorylation of YAP (Yes-associated protein), a readout of activated Hippo signaling, increased after short- and longer-term m …
Effects of high-fat diet and physical activity on pyruvate dehydrogenase kinase-4 in mouse skeletal muscle.
Rinnankoski-Tuikka R, Silvennoinen M, Torvinen S, Hulmi JJ, Lehti M, Kivelä R, Reunanen H, Kainulainen H. Rinnankoski-Tuikka R, et al. Among authors: hulmi jj. Nutr Metab (Lond). 2012 Jun 9;9(1):53. doi: 10.1186/1743-7075-9-53. Nutr Metab (Lond). 2012. PMID: 22682013 Free PMC article.
It is previously shown that peroxisome proliferator-activated receptor gamma coactivator 1alpha (PGC-1alpha), a master regulator of energy metabolism, coactivates in cell lines pyruvate dehydrogenase kinase-4 (PDK4) gene expression via the estrogen-related receptor alpha (ERRalph …
It is previously shown that peroxisome proliferator-activated receptor gamma coactivator 1alpha (PGC-1alpha), a master regulator of energy m …
14 results