Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My NCBI Filters

Text availability

Article attribute

Article type

Publication date

Search Results

14 results

Filters applied: . Clear all
Page 1
Long-Term Efficacy and Safety of Brigatinib in Crizotinib-Refractory ALK+ NSCLC: Final Results of the Phase 1/2 and Randomized Phase 2 (ALTA) Trials.
Gettinger SN, Huber RM, Kim DW, Bazhenova L, Hansen KH, Tiseo M, Langer CJ, Paz-Ares Rodríguez LG, West HL, Reckamp KL, Weiss GJ, Smit EF, Hochmair MJ, Kim SW, Ahn MJ, Kim ES, Groen HJM, Pye J, Liu Y, Zhang P, Vranceanu F, Camidge DR. Gettinger SN, et al. Among authors: huber rm. JTO Clin Res Rep. 2022 Jul 31;3(9):100385. doi: 10.1016/j.jtocrr.2022.100385. eCollection 2022 Sep. JTO Clin Res Rep. 2022. PMID: 36065449 Free PMC article.
INTRODUCTION: We report brigatinib long-term efficacy and safety from phase 1/2 and phase 2 (ALTA) trials in ALK-rearrangement positive (ALK+) NSCLC. ...No new safety signals were identified versus previous analyses. CONCLUSIONS: Brigatinib exhibited sustained long-term …
INTRODUCTION: We report brigatinib long-term efficacy and safety from phase 1/2 and phase 2 (ALTA) trials in ALK-rearrangement positi …
Continuous Digital Monitoring of Walking Speed in Frail Elderly Patients: Noninterventional Validation Study and Longitudinal Clinical Trial.
Mueller A, Hoefling HA, Muaremi A, Praestgaard J, Walsh LC, Bunte O, Huber RM, Fürmetz J, Keppler AM, Schieker M, Böcker W, Roubenoff R, Brachat S, Rooks DS, Clay I. Mueller A, et al. Among authors: huber rm. JMIR Mhealth Uhealth. 2019 Nov 27;7(11):e15191. doi: 10.2196/15191. JMIR Mhealth Uhealth. 2019. PMID: 31774406 Free PMC article.
CONCLUSIONS: This study showed, for the first time, accurate capture of real-world gait speed in slow-walking older adults with sarcopenia. We demonstrated the feasibility of long-term digital monitoring of mobility in geriatric populations, establishing that sufficient da …
CONCLUSIONS: This study showed, for the first time, accurate capture of real-world gait speed in slow-walking older adults with sarcopenia. …
Characteristics and treatment of new-onset arthritis after checkpoint inhibitor therapy.
Leipe J, Christ LA, Arnoldi AP, Mille E, Berger F, Heppt M, Goldscheider I, Kauffmann-Guerrero D, Huber RM, Dechant C, Berking C, Schulze-Koops H, Skapenko A. Leipe J, et al. Among authors: huber rm. RMD Open. 2018 Aug 17;4(2):e000714. doi: 10.1136/rmdopen-2018-000714. eCollection 2018. RMD Open. 2018. PMID: 30167328 Free PMC article.
Six patients who flared on glucocorticoid treatment on tapering were given methotrexate resulting in long-term remission. Patients with synovitis were more likely to have good tumour response. ...
Six patients who flared on glucocorticoid treatment on tapering were given methotrexate resulting in long-term remission. Patients wi …
Heterogeneous pattern of differences in respiratory parameters between elderly with either good or poor FEV1.
Karrasch S, Behr J, Huber RM, Nowak D, Peters A, Peters S, Holle R, Jörres RA, Schulz H; KORA Study Group. Karrasch S, et al. Among authors: huber rm. BMC Pulm Med. 2018 Feb 6;18(1):27. doi: 10.1186/s12890-018-0582-z. BMC Pulm Med. 2018. PMID: 29409487 Free PMC article.
Thus, the concept of a general "lung age" as suggested by the widespread use of this term in connection with spirometry should be considered with caution....
Thus, the concept of a general "lung age" as suggested by the widespread use of this term in connection with spirometry should be con …
Pathway Targeted Immunotherapy: Rationale and Evidence of Durable Clinical Responses with a Novel, EGF-directed Agent for Advanced NSCLC.
Rosell R, Neninger E, Nicolson M, Huber RM, Thongprasert S, Parikh PM, D'Hondt E. Rosell R, et al. Among authors: huber rm. J Thorac Oncol. 2016 Nov;11(11):1954-1961. doi: 10.1016/j.jtho.2016.08.132. Epub 2016 Aug 24. J Thorac Oncol. 2016. PMID: 27566188 Free article.
The OS benefit from active versus control treatment was 6.7 months. More than 15% of patients had responses for >5 years. Long-term survivors are seen in all EGF PTI trials. Treatment is well-tolerated, induces high anti-EGF antibody titers, reduces levels of circulatin …
The OS benefit from active versus control treatment was 6.7 months. More than 15% of patients had responses for >5 years. Long-term …
Tracheobronchial stents in mucopolysaccharidosis.
Karl R, Carola S, Regina E, Thomas N, Huber RM. Karl R, et al. Among authors: huber rm. Int J Pediatr Otorhinolaryngol. 2016 Apr;83:187-92. doi: 10.1016/j.ijporl.2016.02.015. Epub 2016 Feb 22. Int J Pediatr Otorhinolaryngol. 2016. PMID: 26968075
The first patient could be weaned from mechanical ventilation after stent placement but showed significant long-term stent-related morbidity. The second patient suffered a severe procedure-related complication due to positioning problems typical for MPS. CONCLUSIONS: Very …
The first patient could be weaned from mechanical ventilation after stent placement but showed significant long-term stent-related mo …
Organ-cocultures (COCs) for long term in vitro studies of lung cancer using 2-photon microscopy.
Edelmann M, Tufman A, Huber RM, Bergner A. Edelmann M, et al. Among authors: huber rm. Technol Cancer Res Treat. 2011 Jun;10(3):275-9. doi: 10.7785/tcrt.2012.500203. Technol Cancer Res Treat. 2011. PMID: 21517134 Free article.
Three-dimensional organ cultures allow performing research in vitro in a complex multi-cellular environment. We aimed at developing a long term coculture system (COC) for the study of lung cancer to repeatedly measure tumor volume. ...In this study we present a coculture s …
Three-dimensional organ cultures allow performing research in vitro in a complex multi-cellular environment. We aimed at developing a long …
Lung function in adult patients with cystic fibrosis after using the eFlow rapid for one year.
Naehrig S, Lang S, Schiffl H, Huber RM, Fischer R. Naehrig S, et al. Among authors: huber rm. Eur J Med Res. 2011 Feb 24;16(2):63-6. doi: 10.1186/2047-783x-16-2-63. Eur J Med Res. 2011. PMID: 21463983 Free PMC article. Clinical Trial.
BACKGROUND: The new generation nebuliser PARI eFlow rapid allows a highly efficient aerosol delivery at reduced inhalation time. However, lung function data during long-term use of this device are not available until now. METHODS: 70 clinically stable adult cystic fibrosis …
BACKGROUND: The new generation nebuliser PARI eFlow rapid allows a highly efficient aerosol delivery at reduced inhalation time. However, lu …
International association for the study of lung cancer/american thoracic society/european respiratory society international multidisciplinary classification of lung adenocarcinoma.
Travis WD, Brambilla E, Noguchi M, Nicholson AG, Geisinger KR, Yatabe Y, Beer DG, Powell CA, Riely GJ, Van Schil PE, Garg K, Austin JH, Asamura H, Rusch VW, Hirsch FR, Scagliotti G, Mitsudomi T, Huber RM, Ishikawa Y, Jett J, Sanchez-Cespedes M, Sculier JP, Takahashi T, Tsuboi M, Vansteenkiste J, Wistuba I, Yang PC, Aberle D, Brambilla C, Flieder D, Franklin W, Gazdar A, Gould M, Hasleton P, Henderson D, Johnson B, Johnson D, Kerr K, Kuriyama K, Lee JS, Miller VA, Petersen I, Roggli V, Rosell R, Saijo N, Thunnissen E, Tsao M, Yankelewitz D. Travis WD, et al. Among authors: huber rm. J Thorac Oncol. 2011 Feb;6(2):244-85. doi: 10.1097/JTO.0b013e318206a221. J Thorac Oncol. 2011. PMID: 21252716 Free PMC article. Review.
If the tumor cannot be classified based on light microscopy alone, special studies such as immunohistochemistry and/or mucin stains should be applied to classify the tumor further. Use of the term NSCLC not otherwise specified should be minimized. CONCLUSIONS: This new cla …
If the tumor cannot be classified based on light microscopy alone, special studies such as immunohistochemistry and/or mucin stains should b …
Pulmonary function in patients with type 1 diabetes before and after simultaneous pancreas and kidney transplantation.
Dieterle CD, Schmauss S, Arbogast H, Domsch C, Huber RM, Landgraf R. Dieterle CD, et al. Among authors: huber rm. Transplantation. 2007 Mar 15;83(5):566-9. doi: 10.1097/01.tp.0000253882.95177.61. Transplantation. 2007. PMID: 17353775
CONCLUSION: Simultaneous pancreas and kidney transplantation is able to attain long-term normoglycemia and to improve pulmonary function in uremic type 1 diabetic patients....
CONCLUSION: Simultaneous pancreas and kidney transplantation is able to attain long-term normoglycemia and to improve pulmonary funct …
14 results