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Maternal and Newborn Hospital Outcomes of Perinatal SARS-CoV-2 Infection: A National Registry.
Hudak ML, Flannery DD, Barnette K, Getzlaff T, Gautam S, Dhudasia MB, Mukhopadhyay S, Pfeifer MR, Ellington SR, Galang RR, Snead MC, Woodworth KR, Zapata LB, Puopolo KM; AMERICAN ACADEMY OF PEDIATRICS NPC-19 REGISTRY INVESTIGATORS. Hudak ML, et al. Pediatrics. 2023 Feb 1;151(2):e2022059595. doi: 10.1542/peds.2022-059595. Pediatrics. 2023. PMID: 36995183
CONCLUSIONS: Early in the pandemic, SARS-CoV-2 infection was acquired by newborns at variable rates and without apparent short-term effects. During a period that preceded widespread availability of vaccines, we observed higher than expected numbers of preterm births and ma …
CONCLUSIONS: Early in the pandemic, SARS-CoV-2 infection was acquired by newborns at variable rates and without apparent short-term e …
Cardiac remodelling predicts outcome in patients with chronic heart failure.
Xu L, Pagano J, Chow K, Oudit GY, Haykowsky MJ, Mikami Y, Howarth AG, White JA, Howlett JG, Dyck JRB, Anderson TJ, Ezekowitz JA, Thompson RB, Paterson DI. Xu L, et al. Among authors: howlett jg. ESC Heart Fail. 2021 Dec;8(6):5352-5362. doi: 10.1002/ehf2.13626. Epub 2021 Sep 26. ESC Heart Fail. 2021. PMID: 34569184 Free PMC article.
CONCLUSIONS: Cardiac remodelling is common during serial CMR assessment of patients with chronic HF. Change in LV mass predicted long-term outcomes whereas change in left ventricular ejection fraction did not....
CONCLUSIONS: Cardiac remodelling is common during serial CMR assessment of patients with chronic HF. Change in LV mass predicted long-ter
Extrapolating Long-term Event-Free and Overall Survival With Dapagliflozin in Patients With Heart Failure and Reduced Ejection Fraction: An Exploratory Analysis of a Phase 3 Randomized Clinical Trial.
Docherty KF, Jhund PS, Claggett B, Ferreira JP, Bengtsson O, Inzucchi SE, Køber L, Kosiborod MN, Langkilde AM, Martinez FA, Ponikowski P, Sabatine MS, Sjöstrand M, Solomon SD, McMurray JJV; DAPA-HF Investigators and Committees. Docherty KF, et al. JAMA Cardiol. 2021 Nov 1;6(11):1298-1305. doi: 10.1001/jamacardio.2021.2632. JAMA Cardiol. 2021. PMID: 34319398 Free PMC article. Clinical Trial.
OBJECTIVE: To estimate the projected long-term treatment effects of dapagliflozin in patients with HFrEF over the duration of a patient's lifetime. ...The trial results were extrapolated to estimate the projected long-term treatment effects of dapagliflozin over the …
OBJECTIVE: To estimate the projected long-term treatment effects of dapagliflozin in patients with HFrEF over the duration of a patie …
Circulating troponin and further left ventricular ejection fraction improvement in patients with previously recovered left ventricular ejection fraction.
Howlett JG, Sharma N, Alemayehu WG, Dyck JRB, Anderson T, Fine N, Becker H, White JA, Paterson DI, Thompson RB, Oudit GY, Haykowsky MJ, Ezekowitz JA. Howlett JG, et al. ESC Heart Fail. 2020 Oct;7(5):2725-2733. doi: 10.1002/ehf2.12863. Epub 2020 Jun 27. ESC Heart Fail. 2020. PMID: 32592541 Free PMC article.
AIMS: The aim of this study is to determine factors associated with long-term recovery of left ventricular ejection fraction (LVEF) in patients with heart failure with reduced EF (HFrEF) and if further recovery also occurs in this group. ...
AIMS: The aim of this study is to determine factors associated with long-term recovery of left ventricular ejection fraction (LVEF) i …
Are direct oral anticoagulants an economically attractive alternative to low molecular weight heparins in lung cancer associated venous thromboembolism management?
Howlett J, Benzenine E, Fagnoni P, Quantin C. Howlett J, et al. J Thromb Thrombolysis. 2020 Oct;50(3):642-651. doi: 10.1007/s11239-020-02047-1. J Thromb Thrombolysis. 2020. PMID: 32020515
Venous thromboembolism is highly prevalent in lung cancer patients. Low molecular weight heparins are recommended for long term treatment of cancer associated venous thromboembolism. Direct oral anticoagulants are however an interesting alternative as they are administered …
Venous thromboembolism is highly prevalent in lung cancer patients. Low molecular weight heparins are recommended for long term treat …
Physicians' guideline adherence is associated with long-term heart failure mortality in outpatients with heart failure with reduced ejection fraction: the QUALIFY international registry.
Komajda M, Schöpe J, Wagenpfeil S, Tavazzi L, Böhm M, Ponikowski P, Anker SD, Filippatos GS, Cowie MR; QUALIFY Investigators. Komajda M, et al. Eur J Heart Fail. 2019 Jul;21(7):921-929. doi: 10.1002/ejhf.1459. Epub 2019 Apr 1. Eur J Heart Fail. 2019. PMID: 30933403 Free article.
BACKGROUND: Physicians' adherence to guideline-recommended therapy is associated with short-term clinical outcomes in heart failure (HF) with reduced ejection fraction (HFrEF). However, its impact on longer-term outcomes is poorly documented. Here, we present result …
BACKGROUND: Physicians' adherence to guideline-recommended therapy is associated with short-term clinical outcomes in heart failure ( …
Training nurses in a competency framework to support adults with epilepsy and intellectual disability: the EpAID cluster RCT.
Ring H, Howlett J, Pennington M, Smith C, Redley M, Murphy C, Hook R, Platt A, Gilbert N, Jones E, Kelly J, Pullen A, Mander A, Donaldson C, Rowe S, Wason J, Irvine F. Ring H, et al. Among authors: howlett j. Health Technol Assess. 2018 Feb;22(10):1-104. doi: 10.3310/hta22100. Health Technol Assess. 2018. PMID: 29457585 Free PMC article. Clinical Trial.
Future research could explore the specific value of the competency framework for those with a mild to moderate ID and the potential for greater long-term benefits arising from the continuing professional development element of the framework. ...
Future research could explore the specific value of the competency framework for those with a mild to moderate ID and the potential for grea …
Clinical practices and attitudes regarding the diagnosis and management of heart failure: findings from the CORE Needs Assessment Survey.
Howlett J, Comin-Colet J, Dickstein K, Fuat A, Pölzl G, Delaney S. Howlett J, et al. ESC Heart Fail. 2018 Feb;5(1):172-183. doi: 10.1002/ehf2.12205. Epub 2017 Sep 18. ESC Heart Fail. 2018. PMID: 28921886 Free PMC article. Review.
Results revealed multiple gaps over the spectrum of HF care, including diagnosis (low recognition of the signs and symptoms of HF and limited use of diagnostic tests), treatment planning (underuse of recommended agents and subtherapeutic dosing), treatment monitoring and adjustme …
Results revealed multiple gaps over the spectrum of HF care, including diagnosis (low recognition of the signs and symptoms of HF and limite …
Differences in treatment, outcomes, and quality of life among patients with heart failure in Canada and the United States.
Kaul P, Reed SD, Hernandez AF, Howlett JG, Ezekowitz JA, Li Y, Zheng Y, Rouleau JL, Starling RC, O'Connor CM, Califf RM, Armstrong PW. Kaul P, et al. Among authors: howlett jg. JACC Heart Fail. 2013 Dec;1(6):523-30. doi: 10.1016/j.jchf.2013.07.004. Epub 2013 Oct 23. JACC Heart Fail. 2013. PMID: 24622005 Free article. Clinical Trial.
Further study on how cardiac care is delivered in the 2 countries and how it influences the results of clinical trials and population-level outcomes, especially in the long term, is warranted. (A Study Testing the Effectiveness of Nesiritide in Patients With Acute Decompen …
Further study on how cardiac care is delivered in the 2 countries and how it influences the results of clinical trials and population-level …
23 results