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Embedding clinical interventions into observational studies.
Newman AB, Avilés-Santa ML, Anderson G, Heiss G, Howard WJ, Krucoff M, Kuller LH, Lewis CE, Robinson JG, Taylor H, Treviño RP, Weintraub W. Newman AB, et al. Among authors: howard wj. Contemp Clin Trials. 2016 Jan;46:100-105. doi: 10.1016/j.cct.2015.11.017. Epub 2015 Dec 2. Contemp Clin Trials. 2016. PMID: 26611435 Free PMC article.
Hybrid designs that combine elements of clinical trials with observational registries or cohort studies should be considered as part of a long-term strategy to transform clinical trials and epidemiology, adapting to the opportunities of big data and the challenges of const …
Hybrid designs that combine elements of clinical trials with observational registries or cohort studies should be considered as part of a lo …
Effect of lower targets for blood pressure and LDL cholesterol on atherosclerosis in diabetes: the SANDS randomized trial.
Howard BV, Roman MJ, Devereux RB, Fleg JL, Galloway JM, Henderson JA, Howard WJ, Lee ET, Mete M, Poolaw B, Ratner RE, Russell M, Silverman A, Stylianou M, Umans JG, Wang W, Weir MR, Weissman NJ, Wilson C, Yeh F, Zhu J. Howard BV, et al. Among authors: howard wj. JAMA. 2008 Apr 9;299(14):1678-89. doi: 10.1001/jama.299.14.1678. JAMA. 2008. PMID: 18398080 Free PMC article. Clinical Trial.
Further follow-up is needed to determine whether these improvements will result in lower long-term CVD event rates and costs and favorable risk-benefit outcomes. ...
Further follow-up is needed to determine whether these improvements will result in lower long-term CVD event rates and costs and favo …
Gaps in public knowledge of peripheral arterial disease: the first national PAD public awareness survey.
Hirsch AT, Murphy TP, Lovell MB, Twillman G, Treat-Jacobson D, Harwood EM, Mohler ER 3rd, Creager MA, Hobson RW 2nd, Robertson RM, Howard WJ, Schroeder P, Criqui MH; Peripheral Arterial Disease Coalition. Hirsch AT, et al. Among authors: howard wj. Circulation. 2007 Oct 30;116(18):2086-94. doi: 10.1161/CIRCULATIONAHA.107.725101. Epub 2007 Sep 17. Circulation. 2007. PMID: 17875966
CONCLUSIONS: The public is poorly informed about PAD, with major knowledge gaps regarding the definition of PAD, risk factors that lead to PAD, and associated limb symptoms and amputation risk. The public is not aware that PAD imposes a high short-term risk of heart attack …
CONCLUSIONS: The public is poorly informed about PAD, with major knowledge gaps regarding the definition of PAD, risk factors that lead to P …
Long-term cholesterol-lowering effects of psyllium as an adjunct to diet therapy in the treatment of hypercholesterolemia.
Anderson JW, Davidson MH, Blonde L, Brown WV, Howard WJ, Ginsberg H, Allgood LD, Weingand KW. Anderson JW, et al. Among authors: howard wj. Am J Clin Nutr. 2000 Jun;71(6):1433-8. doi: 10.1093/ajcn/71.6.1433. Am J Clin Nutr. 2000. PMID: 10837282 Clinical Trial.
BACKGROUND: Hypercholesterolemia is a major risk factor for coronary heart disease and nutrition management is the initial therapeutic approach. OBJECTIVE: This multicenter study evaluated the long-term effectiveness of psyllium husk fiber as an adjunct to diet in the trea …
BACKGROUND: Hypercholesterolemia is a major risk factor for coronary heart disease and nutrition management is the initial therapeutic appro …
Long-term treatment of hypercholesterolemia with dietary fiber.
Hunninghake DB, Miller VT, LaRosa JC, Kinosian B, Jacobson T, Brown V, Howard WJ, Edelman DA, O'Connor RR. Hunninghake DB, et al. Among authors: howard wj. Am J Med. 1994 Dec;97(6):504-8. doi: 10.1016/0002-9343(94)90344-1. Am J Med. 1994. PMID: 7985708 Clinical Trial.
PURPOSE: To evaluate the hypocholesterolemic effects of long-term treatment (36 to 51 weeks) with a mixture of dietary fibers (guar gum, pectin, soy, pea, corn bran) administered twice a day. ...
PURPOSE: To evaluate the hypocholesterolemic effects of long-term treatment (36 to 51 weeks) with a mixture of dietary fibers (guar g …