Absence of ANGPTL4 in adipose tissue improves glucose tolerance and attenuates atherogenesis.
Aryal B, Singh AK, Zhang X, Varela L, Rotllan N, Goedeke L, Chaube B, Camporez JP, Vatner DF, Horvath TL, Shulman GI, Suárez Y, Fernández-Hernando C.
Aryal B, et al. Among authors: horvath tl.
JCI Insight. 2018 Mar 22;3(6):e97918. doi: 10.1172/jci.insight.97918.
JCI Insight. 2018.
PMID: 29563332
Free PMC article.
As a result, we observed a remarkable improvement in glucose tolerance in short-term HFD-fed AT-specific Angptl4-KO mice. Finally, lack of ANGPTL4 in AT enhances the clearance of proatherogenic lipoproteins, attenuates inflammation, and reduces atherosclerosis. ...
As a result, we observed a remarkable improvement in glucose tolerance in short-term HFD-fed AT-specific Angptl4-KO mice. Finally, la …