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Inhaled hypertonic saline in adults hospitalised for exacerbation of cystic fibrosis lung disease: a retrospective study.
Pezzulo AA, Stoltz DA, Hornick DB, Durairaj L. Pezzulo AA, et al. Among authors: hornick db. BMJ Open. 2012 Apr 19;2(2):e000407. doi: 10.1136/bmjopen-2011-000407. Print 2012. BMJ Open. 2012. PMID: 22517980 Free PMC article.
BACKGROUND: Inhaled hypertonic saline (HTS) improves quality of life and reduces pulmonary exacerbations when given long term in patients with cystic fibrosis (CF). While increasingly being offered for acute pulmonary exacerbations, little is known about the efficacy in th …
BACKGROUND: Inhaled hypertonic saline (HTS) improves quality of life and reduces pulmonary exacerbations when given long term in pati …
Cystic fibrosis transmembrane conductance regulator intracellular processing, trafficking, and opportunities for mutation-specific treatment.
Rogan MP, Stoltz DA, Hornick DB. Rogan MP, et al. Among authors: hornick db. Chest. 2011 Jun;139(6):1480-1490. doi: 10.1378/chest.10-2077. Chest. 2011. PMID: 21652558 Review.
We review the results of encouraging clinical trials examining orally administered therapeutics, including agents that promote read-through of class I mutations (premature termination codons); correctors, which overcome the CFTR misfolding that characterizes the common class II m …
We review the results of encouraging clinical trials examining orally administered therapeutics, including agents that promote read-through …