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Fear extinction rescuing effects of dopamine and L-DOPA in the ventromedial prefrontal cortex.
Sartori SB, Keil TMV, Kummer KK, Murphy CP, Gunduz-Cinar O, Kress M, Ebner K, Holmes A, Singewald N. Sartori SB, et al. Among authors: holmes a. Transl Psychiatry. 2024 Jan 8;14(1):11. doi: 10.1038/s41398-023-02708-8. Transl Psychiatry. 2024. PMID: 38191458 Free PMC article.
Conversely, direct microinfusion of DA into IL produced long-term fear extinction (an effect that was insensitive to -/ss-adrenoreceptor antagonism). ...
Conversely, direct microinfusion of DA into IL produced long-term fear extinction (an effect that was insensitive to -/ss-adrenorecep …
Assessing the Human Health Benefits of Climate Mitigation, Pollution Prevention, and Biodiversity Preservation.
Landrigan PJ, Britt M, Fisher S, Holmes A, Kumar M, Mu J, Rizzo I, Sather A, Yousuf A, Kumar P. Landrigan PJ, et al. Among authors: holmes a. Ann Glob Health. 2024 Jan 5;90(1):1. doi: 10.5334/aogh.4161. eCollection 2024. Ann Glob Health. 2024. PMID: 38186855 Free PMC article.
They are guided by an economic model that focuses almost exclusively on short-term gain, while ignoring natural capital and human capital. They have relied on the combustion of vast quantities of fossil fuels, massive consumption of the earth's resources, and production an …
They are guided by an economic model that focuses almost exclusively on short-term gain, while ignoring natural capital and human cap …
Mechanisms of Atrial Fibrillation in Obstructive Sleep Apnoea.
Saleeb-Mousa J, Nathanael D, Coney AM, Kalla M, Brain KL, Holmes AP. Saleeb-Mousa J, et al. Among authors: holmes ap. Cells. 2023 Jun 19;12(12):1661. doi: 10.3390/cells12121661. Cells. 2023. PMID: 37371131 Free PMC article. Review.
Chronic intermittent hypoxia (CIH), a key feature of OSA, is associated with long-term adaptive changes in myocyte ion channel currents, sensitising the atria to episodic bursts of autonomic reflex activity. ...
Chronic intermittent hypoxia (CIH), a key feature of OSA, is associated with long-term adaptive changes in myocyte ion channel curren …
Associations of postoperative delirium with activities of daily living in older people after major surgery: A prospective cohort study.
Aldwikat RK, Manias E, Holmes AC, Tomlinson E, Nicholson P. Aldwikat RK, et al. Among authors: holmes ac. J Clin Nurs. 2023 Oct;32(19-20):7578-7588. doi: 10.1111/jocn.16801. Epub 2023 Jun 21. J Clin Nurs. 2023. PMID: 37341067
BACKGROUND: Previous studies have focused on the association between postoperative delirium and long-term function decline, however the association between postoperative delirium and the ability to perform ADL, particularly in the immediate postoperative period, needs furt …
BACKGROUND: Previous studies have focused on the association between postoperative delirium and long-term function decline, however t …
Cohort profile: the BABY1000 pilot prospective longitudinal birth cohort study based in Sydney, Australia.
Grech AM, Kizirian N, Lal R, Zankl A, Birkner K, Nasir R, Muirhead R, Sau-Harvey R, Haghighi MM, Collins C, Holmes A, Skilton M, Simpson S, Gordon A. Grech AM, et al. Among authors: holmes a. BMJ Open. 2023 Jun 8;13(6):e068275. doi: 10.1136/bmjopen-2022-068275. BMJ Open. 2023. PMID: 37290940 Free PMC article.
Since there are very few cohort studies in early pregnancy, gaps remain in our understanding of the mechanisms underpinning these relationships, and how health may be optimised. 'BABY1000', a pilot prospective longitudinal birth cohort study, aims to (1) identify factors b …
Since there are very few cohort studies in early pregnancy, gaps remain in our understanding of the mechanisms underpinning these relationsh …
Risk of Aneurysm Rupture (ROAR) study: protocol for a long-term, longitudinal, UK multicentre study of unruptured intracranial aneurysms.
Hall S, Birks J, Anderson I, Bacon A, Brennan PM, Bennett D, Chavredakis E, Critchley G, Dow G, Downer J, Galea J, Grover P, Gurusinghe N, Helmy A, Kounin G, Mukerji N, Patel H, Patel J, Ross N, St George J, Teo M, Tolias CM, Tzerakis N, Uff C, van Beijum J, Veighey K, White E, Whitfield P, Bulters DO; ROAR Investigators. Hall S, et al. BMJ Open. 2023 Mar 16;13(3):e070504. doi: 10.1136/bmjopen-2022-070504. BMJ Open. 2023. PMID: 36927598 Free PMC article.
There are also many potential predictors not considered in PHASES that require evaluation, and the estimated rupture risk is largely based on short-term follow-up (mostly 1 year). The aims of this study are to: (1) test the accuracy of PHASES in a UK population, (2) evalua …
There are also many potential predictors not considered in PHASES that require evaluation, and the estimated rupture risk is largely based o …
Genomic epidemiology of SARS-CoV-2 in a university outbreak setting and implications for public health planning.
Nickbakhsh S, Hughes J, Christofidis N, Griffiths E, Shaaban S, Enright J, Smollett K, Nomikou K, Palmalux N, Tong L, Carmichael S, Sreenu VB, Orton R, Goldstein EJ, Tomb RM; COVID-19 Genomics UK (COG-UK) Consortium; Templeton K, Gunson RN, da Silva Filipe A, Milosevic C, Thomson E, Robertson DL, Holden MTG, Illingworth CJR, Smith-Palmer A. Nickbakhsh S, et al. Sci Rep. 2022 Jul 19;12(1):11735. doi: 10.1038/s41598-022-15661-1. Sci Rep. 2022. PMID: 35853960 Free PMC article.
One setting at continued risk of COVID-19 outbreaks are higher education institutions, associated with student movements at the start of term, close living conditions within residential halls, and high social contact rates. ...The impact of student infections on the local …
One setting at continued risk of COVID-19 outbreaks are higher education institutions, associated with student movements at the start of …
The Gut Microbiome in Parkinson's Disease: A Longitudinal Study of the Impacts on Disease Progression and the Use of Device-Assisted Therapies.
Lubomski M, Xu X, Holmes AJ, Muller S, Yang JYH, Davis RL, Sue CM. Lubomski M, et al. Among authors: holmes aj. Front Aging Neurosci. 2022 May 17;14:875261. doi: 10.3389/fnagi.2022.875261. eCollection 2022. Front Aging Neurosci. 2022. PMID: 35656540 Free PMC article.
DATs exerted variable GM influences across the short and longer-term. We found that specific GM profiles combined with dietary factors improved prediction of disease progression in PD patients....
DATs exerted variable GM influences across the short and longer-term. We found that specific GM profiles combined with dietary factor …
116 results