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Pharmacologic treatment of abnormal ion transport in the airway epithelium in cystic fibrosis.
Knowles MR, Olivier KN, Hohneker KW, Robinson J, Bennett WD, Boucher RC. Knowles MR, et al. Among authors: hohneker kw. Chest. 1995 Feb;107(2 Suppl):71S-76S. doi: 10.1378/chest.107.2_supplement.71s. Chest. 1995. PMID: 7842817 Review.
Clinical trials of amiloride are currently underway in adults and adolescents, and short-term safety studies have been initiated in children. Aerosolized uridine triphosphate (UTP) induces Cl- (and liquid) secretion in CF airway epithelia via non-CFTR Cl- channels. Short- …
Clinical trials of amiloride are currently underway in adults and adolescents, and short-term safety studies have been initiated in c …