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Pharmacologic treatment of abnormal ion transport in the airway epithelium in cystic fibrosis.
Chest. 1995 Feb;107(2 Suppl):71S-76S. doi: 10.1378/chest.107.2_supplement.71s.
Chest. 1995.
PMID: 7842817
Review.
Clinical trials of amiloride are currently underway in adults and adolescents, and short-term safety studies have been initiated in children. Aerosolized uridine triphosphate (UTP) induces Cl- (and liquid) secretion in CF airway epithelia via non-CFTR Cl- channels. Short- …
Clinical trials of amiloride are currently underway in adults and adolescents, and short-term safety studies have been initiated in c …
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