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Tuberculosis disease in immunocompromised children and adolescents: a pTBnet multi-centre case-control study.
Rodríguez-Molino P, Tebruegge M, Noguera-Julian A, Neth O, Fidler K, Brinkmann F, Sainz T, Ivaskeviciene I, Ritz N, Brito MJ, Milheiro Silva T, Chechenieva V, Serdiuk M, Lancella L, Russo C, Soler-García A, Navarro ML, Krueger R, Feiterna-Sperling C, Starshinova A, Hiteva A, Hoffmann A, Kalibatas P, Lo Vecchio A, Scarano SM, Bustillo M, Blázquez Gamero D, Espiau M, Buonsenso D, Falcón L, Turnbull L, Colino E, Rueda S, Buxbaum C, Carazo B, Alvarez C, Dapena M, Piqueras A, Velizarova S, Ozere I, Götzinger F, Pareja M, Garrote Llanos MI, Soto B, Rodríguez Martín S, Korta JJ, Pérez-Gorricho B, Herranz M, Hernández-Bartolomé Á, Díaz-Almirón M, Kohns Vasconcelos M, Ferreras-Antolín L, Santiago-García B. Rodríguez-Molino P, et al. Among authors: hoffmann a. Clin Infect Dis. 2024 Apr 3:ciae158. doi: 10.1093/cid/ciae158. Online ahead of print. Clin Infect Dis. 2024. PMID: 38568992
Although the mortality in IC children was <1%, the rate of long-term sequelae was significantly higher than in non-IC cases (14.8% vs. 6.1%; p = 0.004). CONCLUSIONS: IC children with TB disease in Europe have increased rates of non-respiratory TB, severe disease, and lo …
Although the mortality in IC children was <1%, the rate of long-term sequelae was significantly higher than in non-IC cases (14.8% …
Monitoring mepolizumab treatment in chronic rhinosinusitis with nasal polyps (CRSwNP): Discontinue, change, continue therapy?
Klimek L, Förster-Ruhrmann U, Olze H, Beule AG, Chaker AM, Hagemann J, Huppertz T, Hoffmann TK, Dazert S, Deitmer T, Strieth S, Wrede H, Schlenter WW, Welkoborsky HJ, Wollenberg B, Becker S, Bärhold F, Klimek F, Casper I, Zuberbier J, Rudack C, Cuevas M, Hintschich CA, Guntinas-Lichius O, Stöver T, Bergmann C, Werminghaus P, Pfaar O, Gosepath J, Gröger M, Beutner C, Laudien M, Weber RK, Hildebrand T, Hoffmann AS, Bachert C. Klimek L, et al. Among authors: hoffmann as. Allergol Select. 2024 Mar 21;8:26-39. doi: 10.5414/ALX02460E. eCollection 2024. Allergol Select. 2024. PMID: 38549814 Free PMC article. Review.
Computer-Aided Diagnosis of Maxillary Sinus Anomalies: Validation and Clinical Correlation.
Bhattacharya D, Becker BT, Behrendt F, Beyersdorff D, Petersen E, Petersen M, Cheng B, Eggert D, Betz C, Schlaefer A, Hoffmann AS. Bhattacharya D, et al. Among authors: hoffmann as. Laryngoscope. 2024 Mar 23. doi: 10.1002/lary.31413. Online ahead of print. Laryngoscope. 2024. PMID: 38520698
METHODS: This study uses Hamburg City Health Study (HCHS) a large, prospective, long-term, population-based cohort study of participants between 45 and 74 years of age. ...
METHODS: This study uses Hamburg City Health Study (HCHS) a large, prospective, long-term, population-based cohort study of participa …
A Comprehensive Overview on Chemotherapy-Induced Cardiotoxicity: Insights into the Underlying Inflammatory and Oxidative Mechanisms.
Nagy A, Börzsei D, Hoffmann A, Török S, Veszelka M, Almási N, Varga C, Szabó R. Nagy A, et al. Among authors: hoffmann a. Cardiovasc Drugs Ther. 2024 Mar 16. doi: 10.1007/s10557-024-07574-0. Online ahead of print. Cardiovasc Drugs Ther. 2024. PMID: 38492161 Review.
These side effects include cardiotoxicity, which can cause irreversible cardiac damages with long-term morbidity and mortality. Despite the continuous in-depth research on anti-cancer drugs, an improved knowledge of the underlying mechanisms of cardiotoxicity are necessary …
These side effects include cardiotoxicity, which can cause irreversible cardiac damages with long-term morbidity and mortality. Despi …
Wolbachia strains wMel and wAlbB differentially affect Aedes aegypti traits related to fecundity.
Maciel-de-Freitas R, Sauer FG, Kliemke K, Garcia GA, Pavan MG, David MR, Schmidt-Chanasit J, Hoffmann A, Lühken R. Maciel-de-Freitas R, et al. Among authors: hoffmann a. Microbiol Spectr. 2024 Apr 2;12(4):e0012824. doi: 10.1128/spectrum.00128-24. Epub 2024 Mar 14. Microbiol Spectr. 2024. PMID: 38483475 Free article.
Further research is needed to better understand the underlying mechanisms responsible for these differences in fitness effects and their potential impact on the long-term efficacy of Wolbachia-based dengue control programs.IMPORTANCEThe transmission of arboviruses such as …
Further research is needed to better understand the underlying mechanisms responsible for these differences in fitness effects and their pot …
13C-Metabolic flux analysis detected a hyperoxemia-induced reduction of tricarboxylic acid cycle metabolism in granulocytes during two models of porcine acute subdural hematoma and hemorrhagic shock.
Wolfschmitt EM, Vogt JA, Hogg M, Wachter U, Stadler N, Kapapa T, Datzmann T, Messerer DAC, Hoffmann A, Gröger M, Münz F, Mathieu R, Mayer S, Merz T, Asfar P, Calzia E, Radermacher P, Zink F. Wolfschmitt EM, et al. Among authors: hoffmann a. Front Immunol. 2024 Jan 9;14:1319986. doi: 10.3389/fimmu.2023.1319986. eCollection 2023. Front Immunol. 2024. PMID: 38332911 Free PMC article.
To uncover the potential impact of increased oxygen fractions on circulating immune cells during intensive care, we have performed a (13)C-metabolic flux analysis (MFA) on PBMCs and granulocytes isolated from two long-term, resuscitated models of combined acute subdural he …
To uncover the potential impact of increased oxygen fractions on circulating immune cells during intensive care, we have performed a (13)C-m …
Myeloid spatial and transcriptional molecular signature of ischemia-reperfusion injury in human liver transplantation.
Sosa RA, Ahn R, Li F, Terry AQ, Qian Z, Bhat A, Sen S, Naini BV, Ito T, Kaldas FM, Hoffmann A, Busuttil RW, Kupiec-Weglinski JW, Gjertson DW, Reed EF. Sosa RA, et al. Among authors: hoffmann a. Hepatol Commun. 2024 Jan 11;8(1):e0330. doi: 10.1097/HC9.0000000000000330. eCollection 2024 Jan 1. Hepatol Commun. 2024. PMID: 38206205 Free PMC article.
BACKGROUND: Ischemia-reperfusion injury (IRI) is a significant clinical concern in liver transplantation, with a key influence on short-term and long-term allograft and patient survival. Myeloid cells trigger and sustain tissue inflammation and damage associated wit …
BACKGROUND: Ischemia-reperfusion injury (IRI) is a significant clinical concern in liver transplantation, with a key influence on short-t …
Adult Cerebral Malaria: Acute and Subacute Imaging Findings, Long-term Clinical Consequences.
Coughlan C, Jäger HR, Brealey D, Carletti F, Hyare H, Pattnaik R, Sahu PK, Mohanty S, Logan S, Hoffmann A, Wassmer SC, Checkley AM. Coughlan C, et al. Among authors: hoffmann a. Clin Infect Dis. 2024 Feb 17;78(2):457-460. doi: 10.1093/cid/ciad651. Clin Infect Dis. 2024. PMID: 37897407 Free PMC article.
We show magnetic resonance imaging (MRI) features suggestive of cytotoxic and vasogenic cerebral edema followed by microhemorrhages in 2 adult UK cases, comparing them with an Indian cohort. Long-term follow-up images correlate ongoing changes with residual functional impa …
We show magnetic resonance imaging (MRI) features suggestive of cytotoxic and vasogenic cerebral edema followed by microhemorrhages in 2 adu …
Laminin α4 Expression in Human Adipose Tissue Depots and Its Association with Obesity and Obesity Related Traits.
Hagemann T, Czechowski P, Ghosh A, Sun W, Dong H, Noé F, Wolfrum C, Blüher M, Hoffmann A. Hagemann T, et al. Among authors: hoffmann a. Biomedicines. 2023 Oct 17;11(10):2806. doi: 10.3390/biomedicines11102806. Biomedicines. 2023. PMID: 37893179 Free PMC article.
AT LAMA4 expression was not significantly different between subjects with or without obesity, metabolically healthy versus unhealthy, and obesity before versus after short-term weight loss. Our results support significant associations between obesity related clinical param …
AT LAMA4 expression was not significantly different between subjects with or without obesity, metabolically healthy versus unhealthy, and ob …
156 results