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Impact of Prenatal Diagnosis of Critical Congenital Heart Disease on Preoperative and Postoperative Outcomes.
Dischinger AN, Li JS, Mulder H, Spears T, Chiswell KE, Hoffman TM, Hartman RJ, Walsh MJ, Sang CJ, Sarno LA, Paolillo JA, Welke K, D'Ottavio A, Sethi NJ. Dischinger AN, et al. Among authors: hoffman tm. Pediatr Cardiol. 2023 Oct;44(7):1520-1528. doi: 10.1007/s00246-023-03197-8. Epub 2023 Jun 8. Pediatr Cardiol. 2023. PMID: 37289278
Patients with prenatal diagnosis had a lower incidence of preoperative risk factors, including need for mechanical ventilation and presence of shock. However, prenatally diagnosed patients had worse short-term outcomes, including higher operative mortality, higher incidenc …
Patients with prenatal diagnosis had a lower incidence of preoperative risk factors, including need for mechanical ventilation and presence …
Single-drug immunosuppression is associated with noninferior medium-term survival in pediatric heart transplant recipients.
Watelle L, Touré M, Lamour JM, Kemna MS, Spinner JA, Hoffman TM, Carlo WF, Ballweg JA, Greenway SC, Dallaire F. Watelle L, et al. Among authors: hoffman tm. J Heart Lung Transplant. 2023 Aug;42(8):1074-1081. doi: 10.1016/j.healun.2023.02.1705. Epub 2023 Mar 4. J Heart Lung Transplant. 2023. PMID: 36997361
CONCLUSIONS: For pediatric heart transplant recipients placed on monotherapy, immunosuppression with a single ISD after the first year post-transplant was noninferior to standard therapy with 2 ISDs in the medium term. CONDENSED ABSTRACT: Some children are switched to a si …
CONCLUSIONS: For pediatric heart transplant recipients placed on monotherapy, immunosuppression with a single ISD after the first year post- …
The NHLBI Study on Long-terM OUtcomes after the Multisystem Inflammatory Syndrome In Children (MUSIC): Design and Objectives.
Truong DT, Trachtenberg FL, Pearson GD, Dionne A, Elias MD, Friedman K, Hayes KH, Mahony L, McCrindle BW, Oster ME, Pemberton V, Powell AJ, Russell MW, Shekerdemian LS, Son MB, Taylor M, Newburger JW; MUSIC Study Investigators (Supplement 1). Truong DT, et al. Am Heart J. 2022 Jan;243:43-53. doi: 10.1016/j.ahj.2021.08.003. Epub 2021 Aug 19. Am Heart J. 2022. PMID: 34418362 Free PMC article.
BACKGROUND: The Long-terM OUtcomes after the Multisystem Inflammatory Syndrome In Children (MUSIC) study aims to characterize the frequency and time course of acute and long-term cardiac and non-cardiac sequelae in multisystem inflammatory syndrome in children assoc …
BACKGROUND: The Long-terM OUtcomes after the Multisystem Inflammatory Syndrome In Children (MUSIC) study aims to characterize the fre …
A multi-institutional evaluation of antibody-mediated rejection utilizing the Pediatric Heart Transplant Study database: Incidence, therapies and outcomes.
Thrush PT, Pahl E, Naftel DC, Pruitt E, Everitt MD, Missler H, Zangwill S, Burch M, Hoffman TM, Butts R, Mahle WT. Thrush PT, et al. Among authors: hoffman tm. J Heart Lung Transplant. 2016 Dec;35(12):1497-1504. doi: 10.1016/j.healun.2016.06.014. Epub 2016 Jun 24. J Heart Lung Transplant. 2016. PMID: 27431753
AMR was common and often occurred concurrently with acute cellular rejection. There is wide variability in the treatment of AMR. Short-term patient and graft outcomes were worse for those with treated AMR....
AMR was common and often occurred concurrently with acute cellular rejection. There is wide variability in the treatment of AMR. Short-te …
Early versus delayed umbilical cord clamping in infants with congenital heart disease: a pilot, randomized, controlled trial.
Backes CH, Huang H, Cua CL, Garg V, Smith CV, Yin H, Galantowicz M, Bauer JA, Hoffman TM. Backes CH, et al. Among authors: hoffman tm. J Perinatol. 2015 Oct;35(10):826-31. doi: 10.1038/jp.2015.89. Epub 2015 Jul 30. J Perinatol. 2015. PMID: 26226244 Free PMC article. Clinical Trial.
OBJECTIVE: Delayed umbilical cord clamping (DCC) at birth may provide a better neonatal health status than early umbilical cord clamping (ECC). ...STUDY DESIGN: Pregnant women admitted >37 weeks gestational age with prenatal diagnosis of critical CHD were enrolled and r …
OBJECTIVE: Delayed umbilical cord clamping (DCC) at birth may provide a better neonatal health status than early umbilical cord clamp …
Pediatric heart transplantation-indications and outcomes in the current era.
Thrush PT, Hoffman TM. Thrush PT, et al. Among authors: hoffman tm. J Thorac Dis. 2014 Aug;6(8):1080-96. doi: 10.3978/j.issn.2072-1439.2014.06.16. J Thorac Dis. 2014. PMID: 25132975 Free PMC article. Review.
Research collaboratives are increasingly important in pediatric HTx as single center studies for a limited patient population may not elicit strong enough evidence for practice evolution. Similarly, complications that limit the long term graft survival may occur in a minor …
Research collaboratives are increasingly important in pediatric HTx as single center studies for a limited patient population may not elicit …
Heart failure treatment in the intensive care unit in children.
Jefferies JL, Hoffman TM, Nelson DP. Jefferies JL, et al. Among authors: hoffman tm. Heart Fail Clin. 2010 Oct;6(4):531-58, ix-x. doi: 10.1016/j.hfc.2010.06.001. Heart Fail Clin. 2010. PMID: 20869652 Review.
The primary aim of heart failure therapy is to reduce symptoms, preserve long-term ventricular performance, and prolong survival primarily through antagonism of the neurohormonal compensatory mechanisms. ...
The primary aim of heart failure therapy is to reduce symptoms, preserve long-term ventricular performance, and prolong survival prim …