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Air Pollution Exposure and Interstitial Lung Features in SPIROMICS Participants with COPD.
Baddour NA, Paulin LM, Gassett AJ, Woo H, Hoffman EA, Newell JD Jr, Woodruff PG, Pirozzi CS, Barjaktarevic I, Barr RG, O'Neal W, Han MK, Martinez FJ, Peters SP, Hastie AT, Hansel NN, Ortega VE, Kaufman JD, Sack CS. Baddour NA, et al. Among authors: hoffman ea. Ann Am Thorac Soc. 2024 Apr 3. doi: 10.1513/AnnalsATS.202308-741OC. Online ahead of print. Ann Am Thorac Soc. 2024. PMID: 38568439
Associations between pollutant exposures and risk of ILA were modified by the presence of MUC5B polymorphism (p-value interaction term for NOx = 0.04 and PM2.5 = 0.05) and smoking status (p-value interaction term for NOx = 0.05, NO2 = 0.01, and O3 = 0.05). ...
Associations between pollutant exposures and risk of ILA were modified by the presence of MUC5B polymorphism (p-value interaction term …
Airway Tree Caliber and Susceptibility to Pollution-associated Emphysema: MESA Air and Lung Studies.
Sack C, Wang M, Knutson V, Gassett A, Hoffman EA, Sheppard L, Barr RG, Kaufman JD, Smith B. Sack C, et al. Among authors: hoffman ea. Am J Respir Crit Care Med. 2024 Jan 16. doi: 10.1164/rccm.202307-1248OC. Online ahead of print. Am J Respir Crit Care Med. 2024. PMID: 38226871
Percent emphysema, defined as percentage of lung pixels below -950 Hounsfield units, was assessed up to 5 times per participant via cardiac CT scan (2000-07) and equivalent regions on lung CT scan (2010-18). Long-term outdoor air pollutant concentrations (PM2.5, NOx, O3) w …
Percent emphysema, defined as percentage of lung pixels below -950 Hounsfield units, was assessed up to 5 times per participant via cardiac …
Impact of Marijuana Smoking on COPD Progression in a Cohort of Middle-Aged and Older Persons.
Barjaktarevic I, Cooper CB, Shing T, Buhr RG, Hoffman EA, Woodruff PG, Drummond MB, Kanner RE, Han MK, Hansel NN, Bowler RP, Kinney GL, Jacobson S, Morris MA, Martinez FJ, Ohar J, Couper D, Tashkin DP. Barjaktarevic I, et al. Among authors: hoffman ea. Chronic Obstr Pulm Dis. 2023 Jul 26;10(3):234-247. doi: 10.15326/jcopdf.2022.0378. Chronic Obstr Pulm Dis. 2023. PMID: 37199732 Free PMC article.
Because of our study's limitations, these findings underscore the need for further studies to better understand longer-term effects of marijuana smoking in COPD....
Because of our study's limitations, these findings underscore the need for further studies to better understand longer-term effects o …
Incorporating distance metrics and temporal trends to refine mixed stock analysis.
Stahelin GD, Hoffman EA, Quintana-Ascencio PF, Reusche M, Mansfield KL. Stahelin GD, et al. Among authors: hoffman ea. Sci Rep. 2022 Nov 29;12(1):20569. doi: 10.1038/s41598-022-24279-2. Sci Rep. 2022. PMID: 36446818 Free PMC article.
We demonstrate that shifts in contributions from source populations to mixed stock aggregations are likely associated with nesting population growth. Furthermore, our results highlight the importance of long-term monitoring and the need for periodical reassessment of repro …
We demonstrate that shifts in contributions from source populations to mixed stock aggregations are likely associated with nesting populatio …
Robust Measures of Image-Registration-Derived Lung Biomechanics in SPIROMICS.
Pan Y, Wang D, Chaudhary MFA, Shao W, Gerard SE, Durumeric OC, Bhatt SP, Barr RG, Hoffman EA, Reinhardt JM, Christensen GE. Pan Y, et al. Among authors: hoffman ea. J Imaging. 2022 Nov 16;8(11):309. doi: 10.3390/jimaging8110309. J Imaging. 2022. PMID: 36422058 Free PMC article.
Chronic obstructive pulmonary disease (COPD) is an umbrella term used to define a collection of inflammatory lung diseases that cause airflow obstruction and severe damage to the lung parenchyma. ...
Chronic obstructive pulmonary disease (COPD) is an umbrella term used to define a collection of inflammatory lung diseases that cause …
Contrastive learning and subtyping of post-COVID-19 lung computed tomography images.
Li F, Zhang X, Comellas AP, Hoffman EA, Yang T, Lin CL. Li F, et al. Among authors: hoffman ea. Front Physiol. 2022 Oct 11;13:999263. doi: 10.3389/fphys.2022.999263. eCollection 2022. Front Physiol. 2022. PMID: 36304574 Free PMC article.
Patients who recovered from the novel coronavirus disease 2019 (COVID-19) may experience a range of long-term symptoms. Since the lung is the most common site of the infection, pulmonary sequelae may present persistently in COVID-19 survivors. ...The discovery of post-COVI …
Patients who recovered from the novel coronavirus disease 2019 (COVID-19) may experience a range of long-term symptoms. Since the lun …
Ambient ozone effects on respiratory outcomes among smokers modified by neighborhood poverty: An analysis of SPIROMICS AIR.
Belz DC, Woo H, Putcha N, Paulin LM, Koehler K, Fawzy A, Alexis NE, Barr RG, Comellas AP, Cooper CB, Couper D, Dransfield M, Gassett AJ, Han M, Hoffman EA, Kanner RE, Krishnan JA, Martinez FJ, Paine R 3rd, Peng RD, Peters S, Pirozzi CS, Woodruff PG, Kaufman JD, Hansel NN; SPIROMICS Investigators. Belz DC, et al. Among authors: hoffman ea. Sci Total Environ. 2022 Jul 10;829:154694. doi: 10.1016/j.scitotenv.2022.154694. Epub 2022 Mar 19. Sci Total Environ. 2022. PMID: 35318050 Free PMC article.
Previous studies have also identified adverse respiratory effects of long-term ambient ozone. Factors associated with neighborhood poverty may accentuate the adverse impact of ozone on respiratory health. ...
Previous studies have also identified adverse respiratory effects of long-term ambient ozone. Factors associated with neighborhood po …
Quantitative Chest CT Assessment of Small Airways Disease in Post-Acute SARS-CoV-2 Infection.
Cho JL, Villacreses R, Nagpal P, Guo J, Pezzulo AA, Thurman AL, Hamzeh NY, Blount RJ, Fortis S, Hoffman EA, Zabner J, Comellas AP. Cho JL, et al. Among authors: hoffman ea. Radiology. 2022 Jul;304(1):185-192. doi: 10.1148/radiol.212170. Epub 2022 Mar 15. Radiology. 2022. PMID: 35289657 Free PMC article.
Background The long-term effects of SARS-CoV-2 infection on pulmonary structure and function remain incompletely characterized. ...Conclusion In survivors of COVID-19, small airways disease occurred independently of initial infection severity. The long-term conseque …
Background The long-term effects of SARS-CoV-2 infection on pulmonary structure and function remain incompletely characterized. ...Co …
Polycythemia is Associated with Lower Incidence of Severe COPD Exacerbations in the SPIROMICS Study.
Fawzy A, Woo H, Balasubramanian A, Barjaktarevic I, Barr RG, Bowler RP, Comellas AP, Cooper CB, Couper D, Criner GJ, Dransfield MT, Han MK, Hoffman EA, Kanner RE, Krishnan JA, Martinez FJ, McCormack M, Paine Iii R, Peters S, Wise R, Woodruff PG, Hansel NN, Putcha N. Fawzy A, et al. Among authors: hoffman ea. Chronic Obstr Pulm Dis. 2021 Jul 28;8(3):326-335. doi: 10.15326/jcopdf.2021.0216. Chronic Obstr Pulm Dis. 2021. PMID: 34197703 Free PMC article.
Secondary polycythemia has long been recognized as a consequence of chronic pulmonary disease and hypoxemia and is associated with lower mortality and fewer hospitalizations among individuals with chronic obstructive pulmonary disease (COPD)-prescribed long-term oxygen the …
Secondary polycythemia has long been recognized as a consequence of chronic pulmonary disease and hypoxemia and is associated with lower mor …
Respiratory exacerbations are associated with muscle loss in current and former smokers.
Mason SE, Moreta-Martinez R, Labaki WW, Strand M, Baraghoshi D, Regan EA, Bon J, San Jose Estepar R, Casaburi R, McDonald MN, Rossiter H, Make BJ, Dransfield MT, Han MK, Young KA, Kinney G, Hokanson JE, San Jose Estepar R, Washko GR; COPDGene Investigators; COPDGene® Investigators. Mason SE, et al. Thorax. 2021 Jun;76(6):554-560. doi: 10.1136/thoraxjnl-2020-215999. Epub 2021 Feb 11. Thorax. 2021. PMID: 33574123 Free PMC article.
Acute respiratory exacerbations are associated with reduction of muscle function, but there is a paucity of data on their long-term effect. This study explores the relationship between acute respiratory exacerbations and long-term muscle loss using serial measuremen …
Acute respiratory exacerbations are associated with reduction of muscle function, but there is a paucity of data on their long-term e …
27 results