Altered cardiac metabolic phenotype after prolonged inhibition of NO synthesis in chronically instrumented dogs.
d'Agostino C, Labinskyy V, Lionetti V, Chandler MP, Lei B, Matsuo K, Bellomo M, Xu X, Hintze TH, Stanley WC, Recchia FA.
d'Agostino C, et al. Among authors: hintze th.
Am J Physiol Heart Circ Physiol. 2006 Apr;290(4):H1721-6. doi: 10.1152/ajpheart.00745.2005. Epub 2006 Jan 20.
Am J Physiol Heart Circ Physiol. 2006.
PMID: 16428341
Free article.
We conclude that prolonged NO deficiency causes a profound alteration in cardiac metabolic phenotype, characterized by selective potentiation of carbohydrate oxidation, that cannot be reversed by a short-term infusion of exogenous NO. This phenomenon may constitute an adap …
We conclude that prolonged NO deficiency causes a profound alteration in cardiac metabolic phenotype, characterized by selective potentiatio …