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Investigating hormone-induced changes in affective state using the affective bias test in male and female rats.
Hinchcliffe JK, Mendl M, Robinson ESJ. Hinchcliffe JK, et al. Psychoneuroendocrinology. 2020 May;115:104647. doi: 10.1016/j.psyneuen.2020.104647. Epub 2020 Mar 7. Psychoneuroendocrinology. 2020. PMID: 32179367 Free PMC article.
They also suggest that hormone-induced affective biases influence cognitive and emotional behaviour and could have longer-term effects in some mood disorders....
They also suggest that hormone-induced affective biases influence cognitive and emotional behaviour and could have longer-term effect …
Further validation of the affective bias test for predicting antidepressant and pro-depressant risk: effects of pharmacological and social manipulations in male and female rats.
Hinchcliffe JK, Stuart SA, Mendl M, Robinson ESJ. Hinchcliffe JK, et al. Psychopharmacology (Berl). 2017 Oct;234(20):3105-3116. doi: 10.1007/s00213-017-4687-5. Epub 2017 Jul 22. Psychopharmacology (Berl). 2017. PMID: 28735366 Free PMC article.
CONCLUSIONS: These data add to the translational validity of the ABT and suggest that corticosterone can induce a negative affective bias following acute treatment, an effect which may contribute to its long-term effects on mood....
CONCLUSIONS: These data add to the translational validity of the ABT and suggest that corticosterone can induce a negative affective bias fo …