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Antibiotics in pregnancy influence nasal microbiome and respiratory morbidity in infancy.
Rüttimann C, Nissen-Kratzert A, Mostacci N, Künstle N, Marten A, Gisler A, Bacher K, Yammine S, Steinberg R, Schulzke S, Röösli M, Latzin P, Hilty M, Frey U, Gorlanova O. Rüttimann C, et al. Among authors: hilty m. ERJ Open Res. 2023 Aug 29;9(4):00225-2023. doi: 10.1183/23120541.00225-2023. eCollection 2023 Jul. ERJ Open Res. 2023. PMID: 37650088 Free PMC article.
METHODS: We performed 16S ribosomal RNA gene sequencing (regions V3-V4) on nasal swabs obtained from 296 healthy term infants from the prospective Basel-Bern birth cohort (BILD) at age 4-6 weeks. Information about antibiotic exposure was derived from birth re …
METHODS: We performed 16S ribosomal RNA gene sequencing (regions V3-V4) on nasal swabs obtained from 296 healthy term infants from th …
Artificial intelligence in intensive care: moving towards clinical decision support systems.
Montomoli J, Hilty MP, Ince C. Montomoli J, et al. Among authors: hilty mp. Minerva Anestesiol. 2022 Dec;88(12):1066-1072. doi: 10.23736/S0375-9393.22.16739-8. Epub 2022 Oct 26. Minerva Anestesiol. 2022. PMID: 36287392 Free article. Review.
The high complexity of care in the Intensive Care Unit environment has led, in the last decades, to a big effort in term of the improvement of patient's monitoring devices, increase of diagnostic and therapeutic opportunities, and development of electronic health records. …
The high complexity of care in the Intensive Care Unit environment has led, in the last decades, to a big effort in term of the impro …
Critical care staffing ratio and outcome of COVID-19 patients requiring intensive care unit admission during the first pandemic wave: a retrospective analysis across Switzerland from the RISC-19-ICU observational cohort.
Jeitziner MM, Moser A, Wendel-Garcia PD, Exl MT, Keiser S, Schuepbach RA, Pietsch U, Cereghetti S, Boroli F, Marrel J, Sigg AA, Ksouri H, Schott P, Dullenkopf A, Fleisch I, Heise A, Laurent JC, Jakob SM, Hilty MP, Que YA; RISC-19-ICU Investigators for Switzerland. Jeitziner MM, et al. Among authors: hilty mp. Swiss Med Wkly. 2022 Jun 20;152:w30183. doi: 10.4414/smw.2022.w30183. eCollection 2022 Jun 20. Swiss Med Wkly. 2022. PMID: 35752962 Free article.
CONCLUSION: We found no association of reduced availability of critical care staffing resources in Swiss ICUs with overall ICU length of stay nor mortality. Whether long-term outcome of critically ill patients with COVID-19 have been affected remains to be studied....
CONCLUSION: We found no association of reduced availability of critical care staffing resources in Swiss ICUs with overall ICU length of sta …
Continuous monitoring with wearables in multiple sclerosis reveals an association of cardiac autonomic dysfunction with disease severity.
Hilty M, Oldrati P, Barrios L, Müller T, Blumer C, Foege M, Consortium P, Holz C, Lutterotti A. Hilty M, et al. Mult Scler J Exp Transl Clin. 2022 Jun 1;8(2):20552173221103436. doi: 10.1177/20552173221103436. eCollection 2022 Apr-Jun. Mult Scler J Exp Transl Clin. 2022. PMID: 35677598 Free PMC article.
CONCLUSIONS: Trend-based heart rate variability measured with a wearable provides the opportunity for unobtrusive long-term assessment of autonomic functions in patients with multiple sclerosis. ...
CONCLUSIONS: Trend-based heart rate variability measured with a wearable provides the opportunity for unobtrusive long-term assessmen …
Associations of air pollution and greenness with the nasal microbiota of healthy infants: A longitudinal study.
Gisler A, Korten I, de Hoogh K, Vienneau D, Frey U, Decrue F, Gorlanova O, Soti A, Hilty M, Latzin P, Usemann J; BILD study group. Gisler A, et al. Among authors: hilty m. Environ Res. 2021 Nov;202:111633. doi: 10.1016/j.envres.2021.111633. Epub 2021 Jul 10. Environ Res. 2021. PMID: 34256075 Free article.
BACKGROUND: Air pollution and greenness are associated with short- and long-term respiratory health in children but the underlying mechanisms are only scarcely investigated. ...Thus, an interplay between greenness, air pollution and the early nasal microbiota may contribut …
BACKGROUND: Air pollution and greenness are associated with short- and long-term respiratory health in children but the underlying me …
A Single 60.000 IU Dose of Erythropoietin Does Not Improve Short-Term Aerobic Exercise Performance in Healthy Subjects: A Randomized, Double-Blind, Placebo-Controlled Crossover Trial.
Haider T, Diaz V, Albert J, Alvarez-Sanchez M, Thiersch M, Maggiorini M, Hilty MP, Spengler CM, Gassmann M. Haider T, et al. Among authors: hilty mp. Front Physiol. 2020 Sep 29;11:537389. doi: 10.3389/fphys.2020.537389. eCollection 2020. Front Physiol. 2020. PMID: 33117187 Free PMC article.
Resuscitation with PEGylated carboxyhemoglobin preserves renal cortical oxygenation and improves skeletal muscle microcirculatory flow during endotoxemia.
Guerci P, Ergin B, Kandil A, Ince Y, Heeman P, Hilty MP, Bakker J, Ince C. Guerci P, et al. Among authors: hilty mp. Am J Physiol Renal Physiol. 2020 May 1;318(5):F1271-F1283. doi: 10.1152/ajprenal.00513.2019. Epub 2020 Apr 13. Am J Physiol Renal Physiol. 2020. PMID: 32281418 Free article.
PEGHbCO should be further evaluated as a resuscitation fluid in mid- to long-term models of sepsis-induced acute kidney injury....
PEGHbCO should be further evaluated as a resuscitation fluid in mid- to long-term models of sepsis-induced acute kidney injury....
The pneumococcal polysaccharide capsule and pneumolysin differentially affect CXCL8 and IL-6 release from cells of the upper and lower respiratory tract.
Küng E, Coward WR, Neill DR, Malak HA, Mühlemann K, Kadioglu A, Hilty M, Hathaway LJ. Küng E, et al. Among authors: hilty m. PLoS One. 2014 Mar 24;9(3):e92355. doi: 10.1371/journal.pone.0092355. eCollection 2014. PLoS One. 2014. PMID: 24664110 Free PMC article.
When pneumococci were administered intranasally to mice in a model of long term, stable nasopharyngeal carriage, encapsulated S. pneumoniae remained in the nasopharynx whereas the nonencapsulated pneumococci disseminated into the lungs. ...
When pneumococci were administered intranasally to mice in a model of long term, stable nasopharyngeal carriage, encapsulated S. pneu …
Modulation of the immune system by human milk and infant formula containing nucleotides.
Pickering LK, Granoff DM, Erickson JR, Masor ML, Cordle CT, Schaller JP, Winship TR, Paule CL, Hilty MD. Pickering LK, et al. Among authors: hilty md. Pediatrics. 1998 Feb;101(2):242-9. doi: 10.1542/peds.101.2.242. Pediatrics. 1998. PMID: 9445498 Clinical Trial.
OUTCOME VARIABLES: Antibody responses were determined at 6, 7, and 12 months of age to Haemophilus influenzae type b polysaccharide (Hib), to diphtheria and tetanus toxoids, and to oral polio virus (OPV) immunizations. RESULTS: Of 370 full-term, healthy infants enrolled, 3 …
OUTCOME VARIABLES: Antibody responses were determined at 6, 7, and 12 months of age to Haemophilus influenzae type b polysaccharide (Hib), t …