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Adults with lower-limb amputation: Reduced multifidi muscle activity and extensor muscle endurance is associated with worse physical performance.
Sions JM, Seth M, Beisheim-Ryan EH, Hicks GE, Pohlig RT, Horne JR. Sions JM, et al. Among authors: hicks ge. Clin Physiol Funct Imaging. 2023 Sep;43(5):354-364. doi: 10.1111/cpf.12833. Epub 2023 May 24. Clin Physiol Funct Imaging. 2023. PMID: 37177877
For TUG, nonamputated-side multifidi activity and an interaction term (level x non-amputated-side multifidi activity) explained 9.4% and 6.2% of the total variance, respectively. For 10mWT, beyond covariates, non-amputated-side multifidi activity and the interaction ter …
For TUG, nonamputated-side multifidi activity and an interaction term (level x non-amputated-side multifidi activity) explained 9.4% …
Movement-Evoked Pain Versus Widespread Pain: A Longitudinal Comparison in Older Adults With Chronic Low Back Pain From the Delaware Spine Studies.
Knox PJ, Simon CB, Pohlig RT, Pugliese JM, Coyle PC, Sions JM, Hicks GE. Knox PJ, et al. Among authors: hicks ge. J Pain. 2023 Jun;24(6):980-990. doi: 10.1016/j.jpain.2023.01.012. Epub 2023 Jan 24. J Pain. 2023. PMID: 36706887
It is currently unknown which pain-related factors contribute to long-term disability and poorer perceived health among older adults with chronic low back pain (LBP). ...
It is currently unknown which pain-related factors contribute to long-term disability and poorer perceived health among older adults …
Self-expanding Transcatheter vs Surgical Aortic Valve Replacement in Intermediate-Risk Patients: 5-Year Outcomes of the SURTAVI Randomized Clinical Trial.
Van Mieghem NM, Deeb GM, Søndergaard L, Grube E, Windecker S, Gada H, Mumtaz M, Olsen PS, Heiser JC, Merhi W, Kleiman NS, Chetcuti SJ, Gleason TG, Lee JS, Cheng W, Makkar RR, Crestanello J, George B, George I, Kodali S, Yakubov SJ, Serruys PW, Lange R, Piazza N, Williams MR, Oh JK, Adams DH, Li S, Reardon MJ; SURTAVI Trial Investigators. Van Mieghem NM, et al. JAMA Cardiol. 2022 Oct 1;7(10):1000-1008. doi: 10.1001/jamacardio.2022.2695. JAMA Cardiol. 2022. PMID: 36001335 Free PMC article. Clinical Trial.
IMPORTANCE: In patients with severe aortic valve stenosis at intermediate surgical risk, transcatheter aortic valve replacement (TAVR) with a self-expanding supra-annular valve was noninferior to surgery for all-cause mortality or disabling stroke at 2 years. Comparisons of longe …
IMPORTANCE: In patients with severe aortic valve stenosis at intermediate surgical risk, transcatheter aortic valve replacement (TAVR) with …
A Standardized Assessment of Movement-evoked Pain Ratings Is Associated With Functional Outcomes in Older Adults With Chronic Low Back Pain.
Knox PJ, Simon CB, Pohlig RT, Pugliese JM, Coyle PC, Sions JM, Hicks GE. Knox PJ, et al. Among authors: hicks ge. Clin J Pain. 2021 Dec 24;38(4):241-249. doi: 10.1097/AJP.0000000000001016. Clin J Pain. 2021. PMID: 34954729 Free PMC article.
DISCUSSION: Aggregated posttest MeP independently contributed to worse self-reported and performance-based function among older adults with CLBP. To understand long-term consequences of MeP, future studies should examine longitudinal associations between MeP and function i …
DISCUSSION: Aggregated posttest MeP independently contributed to worse self-reported and performance-based function among older adults with …
The Canadian Rare Diseases Models and Mechanisms (RDMM) Network: Connecting Understudied Genes to Model Organisms.
Boycott KM, Campeau PM, Howley HE, Pavlidis P, Rogic S, Oriel C, Berman JN, Hamilton RM, Hicks GG, Lipshitz HD, Masson JY, Shoubridge EA, Junker A, Leroux MR, McMaster CR, Michaud JL, Turvey SE, Dyment D, Innes AM, van Karnebeek CD, Lehman A, Cohn RD, MacDonald IM, Rachubinski RA, Frosk P, Vandersteen A, Wozniak RW, Pena IA, Wen XY, Lacaze-Masmonteil T, Rankin C, Hieter P. Boycott KM, et al. Among authors: hicks gg. Am J Hum Genet. 2020 Feb 6;106(2):143-152. doi: 10.1016/j.ajhg.2020.01.009. Am J Hum Genet. 2020. PMID: 32032513 Free PMC article.
These collaborations help confirm variant pathogenicity and unravel the molecular mechanisms of RD, and also test novel therapies and lead to long-term collaborations. To expand the impact and reach of this model, we made the RDMM Registry open-source, portable, and custom …
These collaborations help confirm variant pathogenicity and unravel the molecular mechanisms of RD, and also test novel therapies and lead t …
Genome-Wide Transcriptome Landscape of Embryonic Brain-Derived Neural Stem Cells Exposed to Alcohol with Strain-Specific Cross-Examination in BL6 and CD1 Mice.
Xu W, Liyanage VRB, MacAulay A, Levy RD, Curtis K, Olson CO, Zachariah RM, Amiri S, Buist M, Hicks GG, Davie JR, Rastegar M. Xu W, et al. Among authors: hicks gg. Sci Rep. 2019 Jan 18;9(1):206. doi: 10.1038/s41598-018-36059-y. Sci Rep. 2019. PMID: 30659253 Free PMC article.
RNA-seq results showed distinct gene expression patterns and canonical pathways induced by ethanol exposure and withdrawal. Short-term ethanol exposure caused abnormal up-regulation of synaptic pathways, while continuous ethanol treatment profoundly affected brain cells' m …
RNA-seq results showed distinct gene expression patterns and canonical pathways induced by ethanol exposure and withdrawal. Short-term …
Use of trunk muscle training and neuromuscular electrical stimulation to reduce pain and disability in an older adult with chronic low back pain: A case report.
Pugliese JM, Sions JM, Velasco TO, Hicks GE. Pugliese JM, et al. Among authors: hicks ge. Physiother Theory Pract. 2019 Aug;35(8):797-804. doi: 10.1080/09593985.2018.1457745. Epub 2018 Apr 4. Physiother Theory Pract. 2019. PMID: 29617180 Free PMC article.
Her Short Physical Performance Battery summary score improved from 4/12 at baseline to 10/12 at 12 weeks, while her Timed Up and Go test improved from 17.21 to 15.20 s and her Repetitive Trunk Rotation test from 2.72 to 1.93 s/right-left rotation. This case demonstrates a positiv …
Her Short Physical Performance Battery summary score improved from 4/12 at baseline to 10/12 at 12 weeks, while her Timed Up and Go test imp …
Research Agenda for the Prevention of Pain and Its Impact: Report of the Work Group on the Prevention of Acute and Chronic Pain of the Federal Pain Research Strategy.
Gatchel RJ, Reuben DB, Dagenais S, Turk DC, Chou R, Hershey AD, Hicks GE, Licciardone JC, Horn SD. Gatchel RJ, et al. Among authors: hicks ge. J Pain. 2018 Aug;19(8):837-851. doi: 10.1016/j.jpain.2018.02.015. Epub 2018 Mar 22. J Pain. 2018. PMID: 29578089 Free article.
Seven key research priorities were identified. The one deemed "greatest near-term value" was to optimize public health strategies to educate patients on managing pain; that deemed "most impactful" was to determine an association between patient and intervention factors. .. …
Seven key research priorities were identified. The one deemed "greatest near-term value" was to optimize public health strategies to …
Translating to the Community (T2C): a protocol paper describing the development of Canada's first social epigenetic FASD biobank.
Elias B, Hanlon-Dearman A, Head B, Hicks GG. Elias B, et al. Among authors: hicks gg. Biochem Cell Biol. 2018 Apr;96(2):275-287. doi: 10.1139/bcb-2017-0278. Epub 2018 Mar 15. Biochem Cell Biol. 2018. PMID: 29544064
Translating to the Community (T2C) is a social biorepository designed to advance new diagnostic tools and realign community-clinical processes, with the aim to mitigate the short- and long-term impacts of fetal alcohol spectrum disorder (FASD) as well as prenatal alcohol e …
Translating to the Community (T2C) is a social biorepository designed to advance new diagnostic tools and realign community-clinical process …
29 results