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Experience Using Ustekinumab in Pediatric Patients With Medically Refractory Crohn Disease.
Kim FS, Patel PV, Stekol E, Ali S, Hamandi H, Heyman MB, Verstraete SG. Kim FS, et al. Among authors: heyman mb. J Pediatr Gastroenterol Nutr. 2021 Nov 1;73(5):610-614. doi: 10.1097/MPG.0000000000003230. J Pediatr Gastroenterol Nutr. 2021. PMID: 34415711 Free PMC article.
AIM: We conducted a retrospective cohort study to analyze the long-term efficacy of UST, including dose adjustments, in the treatment of pediatric patients with medically refractory CD. ...CONCLUSIONS: Our data suggest that, within our cohort of pediatric patients with CD, …
AIM: We conducted a retrospective cohort study to analyze the long-term efficacy of UST, including dose adjustments, in the treatment …
Association of Baseline Luminal Narrowing With Ileal Microbial Shifts and Gene Expression Programs and Subsequent Transmural Healing in Pediatric Crohn Disease.
Ta AD, Ollberding NJ, Karns R, Haberman Y, Alazraki AL, Hercules D, Baldassano R, Markowitz J, Heyman MB, Kim S, Kirschner B, Shapiro JM, Noe J, Oliva-Hemker M, Otley A, Pfefferkorn M, Kellermayer R, Snapper S, Rabizadeh S, Xavier R, Dubinsky M, Hyams J, Kugathasan S, Jegga AG, Dillman JR, Denson LA. Ta AD, et al. Among authors: heyman mb. Inflamm Bowel Dis. 2021 Oct 20;27(11):1707-1718. doi: 10.1093/ibd/izaa339. Inflamm Bowel Dis. 2021. PMID: 33452801 Free PMC article.
BACKGROUND: Transmural healing (TH) is associated with better long-term outcomes in Crohn disease (CD), whereas pretreatment ileal gene signatures encoding myeloid inflammatory responses and extracellular matrix production are associated with stricturing. ...
BACKGROUND: Transmural healing (TH) is associated with better long-term outcomes in Crohn disease (CD), whereas pretreatment ileal ge …
Maintenance Golimumab Treatment in Pediatric UC Patients With Moderately to Severely Active UC: PURSUIT PEDS PK Long-Term Study Results.
Hyams JS, O'Brien CD, Padgett L, Rosh JR, Turner D, Veereman G, Griffiths AM, Heyman MB, Wahbeh G, Adedokun OJ, Strauss RS, Lynch JP, Chan D. Hyams JS, et al. Among authors: heyman mb. Crohns Colitis 360. 2020 Aug 4;2(4):otaa063. doi: 10.1093/crocol/otaa063. eCollection 2020 Oct. Crohns Colitis 360. 2020. PMID: 36777743 Free PMC article.
BACKGROUND: Long-term safety, pharmacokinetics, and efficacy of open-label golimumab therapy in children with moderate-severe ulcerative colitis were evaluated. ...RESULTS: Among 35 enrolled children, 21 (60%) responded at week 6 and 20 entered the long-term extensi …
BACKGROUND: Long-term safety, pharmacokinetics, and efficacy of open-label golimumab therapy in children with moderate-severe ulcerat …
Variation in Care in the Management of Children With Crohn's Disease: Data From a Multicenter Inception Cohort Study.
Krishnakumar C, Ballengee CR, Liu C, Kim MO, Baker SS, Baldassano RN, Cohen SA, Crandall WV, Denson LA, Dubinsky MC, Evans J, Gokhale R, Griffiths A, Guthery SL, Oliva-Hemker M, Heyman MB, Keljo D, Kellermayer R, Leleiko NS, Mack DR, Markowitz JF, Moulton DE, Noe JD, Otley AR, Patel AS, Pfefferkorn M, Rabizadeh S, Rosh JR, Snapper S, Walters TD, Ziring D, Mondal K, Kappelman MD, Hyams JS, Kugathasan S. Krishnakumar C, et al. Among authors: heyman mb. Inflamm Bowel Dis. 2019 Jun 18;25(7):1208-1217. doi: 10.1093/ibd/izy363. Inflamm Bowel Dis. 2019. PMID: 30601983
CONCLUSIONS: Intercenter variation in care was seen with the initial use of steroids and anti-TNF, but there was no difference in total 3-year exposure to these drugs. Variation in the initiation and long-term use of IMs was significant among sites, but further research wi …
CONCLUSIONS: Intercenter variation in care was seen with the initial use of steroids and anti-TNF, but there was no difference in total 3-ye …
Causal Evaluation of Acute Recurrent and Chronic Pancreatitis in Children: Consensus From the INSPPIRE Group.
Gariepy CE, Heyman MB, Lowe ME, Pohl JF, Werlin SL, Wilschanski M, Barth B, Fishman DS, Freedman SD, Giefer MJ, Gonska T, Himes R, Husain SZ, Morinville VD, Ooi CY, Schwarzenberg SJ, Troendle DM, Yen E, Uc A. Gariepy CE, et al. Among authors: heyman mb. J Pediatr Gastroenterol Nutr. 2017 Jan;64(1):95-103. doi: 10.1097/MPG.0000000000001446. J Pediatr Gastroenterol Nutr. 2017. PMID: 27782962 Free PMC article.
RESULTS: The panel reached consensus on 27 statements covering the definitions of pediatric ARP and CP, evaluation for potential etiologies of these disorders, and long-term monitoring. Statements for which the group reached consensus to make no recommendation or could not …
RESULTS: The panel reached consensus on 27 statements covering the definitions of pediatric ARP and CP, evaluation for potential etiologies …
Early exclusive breastfeeding is associated with longer telomeres in Latino preschool children.
Wojcicki JM, Heyman MB, Elwan D, Lin J, Blackburn E, Epel E. Wojcicki JM, et al. Among authors: heyman mb. Am J Clin Nutr. 2016 Aug;104(2):397-405. doi: 10.3945/ajcn.115.115428. Epub 2016 Jul 20. Am J Clin Nutr. 2016. PMID: 27440083 Free PMC article.
DESIGN: We assessed the relation between dietary, feeding, and weight-associated risk factors measured from birth and TL from blood samples taken at 4 y of age (n = 108) and 5 y of age (n = 92) in a cohort of urban, Latino children (n = 121 individual children). ...CONCLUS …
DESIGN: We assessed the relation between dietary, feeding, and weight-associated risk factors measured from birth and TL from blood s …
High- and low-dose oral delayed-release mesalamine in children with mild-to-moderately active ulcerative colitis.
Winter HS, Krzeski P, Heyman MB, Ibarguen-Secchia E, Iwanczak B, Kaczmarski M, Kierkus J, Kolaček S, Osuntokun B, Quiros JA, Shah M, Yacyshyn B, Dunnmon PM. Winter HS, et al. Among authors: heyman mb. J Pediatr Gastroenterol Nutr. 2014 Dec;59(6):767-72. doi: 10.1097/MPG.0000000000000530. J Pediatr Gastroenterol Nutr. 2014. PMID: 25419597 Free PMC article. Clinical Trial.
CONCLUSIONS: Both low- and high-dose oral, delayed-release mesalamine doses were equally effective as short-term treatment of mild-to-moderately active ulcerative colitis in children, without a specific benefit or risk to using either dose....
CONCLUSIONS: Both low- and high-dose oral, delayed-release mesalamine doses were equally effective as short-term treatment of mild-to …
Quality of life in patients postcolectomy for pediatric-onset ulcerative colitis.
Dalal DH, Patton D, Wojcicki JM, Clark AL, Garnett EA, Heyman MB. Dalal DH, et al. Among authors: heyman mb. J Pediatr Gastroenterol Nutr. 2012 Oct;55(4):425-8. doi: 10.1097/MPG.0b013e318253f2f0. J Pediatr Gastroenterol Nutr. 2012. PMID: 22437468 Free PMC article.
A disease-specific QOL questionnaire (Inflammatory Bowel Disease Questionnaire-32), validated for adults, was used to determine QOL and an additional questionnaire addressing bowel function and reproductive health in long-term follow-up of these patients. RESULTS: Median a …
A disease-specific QOL questionnaire (Inflammatory Bowel Disease Questionnaire-32), validated for adults, was used to determine QOL and an a …
The efficacy of the web-based childhood obesity prevention program in Chinese American adolescents (Web ABC study).
Chen JL, Weiss S, Heyman MB, Cooper B, Lustig RH. Chen JL, et al. Among authors: heyman mb. J Adolesc Health. 2011 Aug;49(2):148-54. doi: 10.1016/j.jadohealth.2010.11.243. Epub 2011 Mar 12. J Adolesc Health. 2011. PMID: 21783046 Free PMC article. Clinical Trial.
CONCLUSION: This web-based behavior program for Chinese American adolescents and their families seems feasible and effective in the short-term. Long-term effects remain to be determined. This type of program can be adapted for other minority ethnic groups who are at …
CONCLUSION: This web-based behavior program for Chinese American adolescents and their families seems feasible and effective in the short- …
Probiotics and prebiotics in pediatrics.
Thomas DW, Greer FR; American Academy of Pediatrics Committee on Nutrition; American Academy of Pediatrics Section on Gastroenterology, Hepatology, and Nutrition. Thomas DW, et al. Pediatrics. 2010 Dec;126(6):1217-31. doi: 10.1542/peds.2010-2548. Epub 2010 Nov 29. Pediatrics. 2010. PMID: 21115585 Review.
There is some evidence that probiotics prevent necrotizing enterocolitis in very low birth weight infants (birth weight between 1000 and 1500 g), but more studies are needed. ...There is a paucity of RCTs examining prebiotics in children, although there may be some …
There is some evidence that probiotics prevent necrotizing enterocolitis in very low birth weight infants (birth weight betwee …
23 results