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Stromal Senescence By Prolonged CDK4/6 Inhibition Potentiates Tumor Growth.
Guan X, LaPak KM, Hennessey RC, Yu CY, Shakya R, Zhang J, Burd CE. Guan X, et al. Among authors: hennessey rc. Mol Cancer Res. 2017 Mar;15(3):237-249. doi: 10.1158/1541-7786.MCR-16-0319. Epub 2016 Dec 30. Mol Cancer Res. 2017. PMID: 28039358 Free PMC article.
Such senescent cells suppress the antitumor immune response and promote melanoma growth in immunocompetent, in vivo models.Implications: The ability of prolonged CDK4/6 inhibitor treatment to induce cellular senescence and a robust SASP in primary cells may hinder therapeutic eff …
Such senescent cells suppress the antitumor immune response and promote melanoma growth in immunocompetent, in vivo models.Implications: The …
Lower respiratory tract infections among human immunodeficiency virus-exposed, uninfected infants.
Mussi-Pinhata MM, Motta F, Freimanis-Hance L, de Souza R, Szyld E, Succi RC, Christie CD, Rolon MJ, Ceriotto M, Read JS; NISDI Perinatal Study Group. Mussi-Pinhata MM, et al. Int J Infect Dis. 2010 Sep;14 Suppl 3:e176-82. doi: 10.1016/j.ijid.2010.01.006. Epub 2010 May 8. Int J Infect Dis. 2010. PMID: 20452798 Free PMC article.
OBJECTIVES: To evaluate whether maternal HIV disease severity during pregnancy is associated with an increased likelihood of lower respiratory tract infections (LRTIs) in HIV-exposed, uninfected infants. METHODS: HIV-exposed, uninfected, singleton, term infants enrolled in …
OBJECTIVES: To evaluate whether maternal HIV disease severity during pregnancy is associated with an increased likelihood of lower respirato …
A cost-conscious establishment of a robotic abdominal wall reconstruction program in a publicly funded healthcare system.
Hennessey RQL, Yang Y, Meneghetti AT, Panton ONM, Chiu CJ. Hennessey RQL, et al. Hernia. 2023 Oct;27(5):1115-1122. doi: 10.1007/s10029-023-02823-x. Epub 2023 Jun 22. Hernia. 2023. PMID: 37347343
PURPOSE: Despite reports of better short-term outcomes, the main criticism for the adoption of the robotic surgery platform for abdominal wall reconstruction (AWR) has been the associated cost, especially in countries with a publicly funded healthcare system such as Canada …
PURPOSE: Despite reports of better short-term outcomes, the main criticism for the adoption of the robotic surgery platform for abdom …
Hepatitis C prevalence in children with perinatal human immunodeficiency virus infection enrolled in a long-term follow-up protocol.
Schuval S, Van Dyke RB, Lindsey JC, Palumbo P, Mofenson LM, Oleske JM, Cervia J, Kovacs A, Dankner WN, Smith E, Nowak B, Ciupak G, Webb N, Eagle M, Smith D, Hennessey R, Goodman-Kerkau M, Levin MJ; Pediatric AIDS Clinical Trials Group Protocol 1028S Team. Schuval S, et al. Among authors: hennessey r. Arch Pediatr Adolesc Med. 2004 Oct;158(10):1007-13. doi: 10.1001/archpedi.158.10.1007. Arch Pediatr Adolesc Med. 2004. PMID: 15466691
PATIENTS: Children with perinatal HIV infection were randomly selected from a large, long-term, follow-up protocol. MAIN OUTCOME MEASURE: Hepatitis C infection was defined as having positive test results on both HCV antibody and HCV RNA assays. ...
PATIENTS: Children with perinatal HIV infection were randomly selected from a large, long-term, follow-up protocol. MAIN OUTCOME MEAS …