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Nerve growth factor-induced PKB/Akt activity is sustained by phosphoinositide 3-kinase dependent and independent signals in sympathetic neurons.
Virdee K, Xue L, Hemmings BA, Goemans C, Heumann R, Tolkovsky AM. Virdee K, et al. Among authors: hemmings ba. Brain Res. 1999 Aug 7;837(1-2):127-42. doi: 10.1016/s0006-8993(99)01643-1. Brain Res. 1999. PMID: 10433995
Phosphoinositide 3-kinase and its downstream effector kinase PKB/Akt have been suggested to have crucial roles in suppressing apoptosis in several classes of neurons. However, few studies have conducted a long-term investigation of either kinase activity, many studies rely …
Phosphoinositide 3-kinase and its downstream effector kinase PKB/Akt have been suggested to have crucial roles in suppressing apoptosis in s …