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Generating Uniformly Cross-Reactive Ebolavirus spp. Anti-nucleoprotein Nanobodies to Facilitate Forward Capable Detection Strategies.
Sherwood LJ, Hayhurst A. Sherwood LJ, et al. Among authors: hayhurst a. ACS Infect Dis. 2022 Feb 11;8(2):343-359. doi: 10.1021/acsinfecdis.1c00478. Epub 2022 Jan 7. ACS Infect Dis. 2022. PMID: 34994194
It is often challenging for a single monoclonal antibody to cross-react equally with all species of a particular viral genus that are separated by time and geographies to ensure broad long-term global immunodiagnostic use. Here, we set out to isolate nanobodies or single-d …
It is often challenging for a single monoclonal antibody to cross-react equally with all species of a particular viral genus that are separa …
Thermostable llama single domain antibodies for detection of botulinum A neurotoxin complex.
Goldman ER, Anderson GP, Conway J, Sherwood LJ, Fech M, Vo B, Liu JL, Hayhurst A. Goldman ER, et al. Among authors: hayhurst a. Anal Chem. 2008 Nov 15;80(22):8583-91. doi: 10.1021/ac8014774. Epub 2008 Oct 24. Anal Chem. 2008. PMID: 18947189 Free PMC article.
The unique properties of these sdAb may provide advantages for many diagnostic applications where long-term storage and in-line monitoring require very rugged yet highly specific recognition elements....
The unique properties of these sdAb may provide advantages for many diagnostic applications where long-term storage and in-line monit …
Luminescent biocompatible quantum dots: a tool for immunosorbent assay design.
Goldman ER, Uyeda HT, Hayhurst A, Mattoussi H. Goldman ER, et al. Among authors: hayhurst a. Methods Mol Biol. 2007;374:207-27. doi: 10.1385/1-59745-369-2:207. Methods Mol Biol. 2007. PMID: 17237541
Furthermore, the QDs strong resistance to photobleaching under continuous illumination relative to many organic dyes makes them ideal fluorophores for long-term cellular imaging studies. This chapter details the materials and methods for the synthesis of surface-functional …
Furthermore, the QDs strong resistance to photobleaching under continuous illumination relative to many organic dyes makes them ideal fluoro …
An efficient method for the rescue and analysis of functional HIV-1 env genes: evidence for recombination in the vicinity of the tat/rev splice site.
Douglas NW, Knight AI, Hayhurst A, Barrett WY, Kevany MJ, Daniels RS. Douglas NW, et al. Among authors: hayhurst a. AIDS. 1996 Jan;10(1):39-46. doi: 10.1097/00002030-199601000-00006. AIDS. 1996. PMID: 8924250
The sequences and translation products generated may be more relevant to disease progression in vivo and vaccine formulations than those obtained from viruses selected in long-term culture....
The sequences and translation products generated may be more relevant to disease progression in vivo and vaccine formulations than those obt …